Results 31 to 40 of about 4,142 (135)

Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

Ophthalmology and Therapy, 2019
Introduction Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues ...
Keisuke Shinno, Kazuya Kurokawa, Seiko Kozai, Akio Kawamura, Katsuhiro Inada, Hideki Tokushige   +5 more
doaj   +1 more source

National Delphi consensus on laser and energy‐based treatments for rosacea

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Various treatments are available for rosacea, including lasers and energy‐based devices (EBDs). However, the specific role of lasers and EBDs in rosacea management remains insufficiently defined in Germany. The aim of the study was to develop a comprehensive expert consensus on the use of lasers and EBDs in the treatment of rosacea ...
Lynhda Nguyen, Nikolaus Seeber, Uwe Paasch, Martin Schaller, Claudia Borelli, Syrus Karsai, Gerd Kautz, Tanja C. Fischer, Michael Drosner, Stefan Hammes, Konstantin Feise, Christian Raulin, Martina Kerscher, Gerd Gauglitz, Jens M. Baron, Stefan W. Schneider, Katharina Herberger   +16 more
wiley   +1 more source

Comparative study of brimonidine and timolol in treatment of glaucoma

MRIMS Journal of Health Sciences, 2015
Background: As population is affected with primary open angle Glaucoma is large. It is important to evaluate drugs which effectively control the intraocular pressure.
Jagadish Chandrarao Narasaiah Lakkineni
doaj   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 387-403, March 2026.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Oral JAK Inhibitors as a Promising Therapeutic Strategy for Refractory Rosacea: A Systematic Review and Meta‐Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Rosacea is a chronic inflammatory dermatosis. While standard therapies exist, managing refractory subtypes remains a therapeutic challenge. Oral Janus kinase (JAK) inhibitors have emerged as potential alternatives, but systematic evidence is lacking. Aims To evaluate the efficacy and safety of oral JAK inhibitors for rosacea through
Yu Peng, Mingzi Sun, Jiayu Chen, Xubo Huang, Fengchuan Zhang   +4 more
wiley   +1 more source

Brimonidine tartrate effect on retinal spreading depression depends on Müller cells

Revista Brasileira de Oftalmologia, 2014
Objective: Demonstrate the Brimonidine effect over Retinal Spreading Depression (SD). Brimonidine is an alpha-2–adrenergic receptor agonist, used in the management of glaucoma. Alpha2-agonists have been shown to be neuroprotective in various experimental
Vinícius Vanzan Pimentel de Oliveira, Marcio Penha Morterá Rodrigues, Adroaldo de Alencar, Sebastião Cronemberger, Nassim Calixto, Adalmir Morterá Dantas   +5 more
doaj   +1 more source

Novel Uses of Brimonidine

Delhi Journal of Ophthalmology
Brimonidine tartrate is a third-generation, highly selective alpha 2 agonist currently available in various formulations and doses to treat ophthalmological conditions. The aim of this article was to review pharmacokinetics, mechanisms, side effects, and
Hikkalagutti. S. Kruthika, Chauhan Tulika, Patyal Sagarika, Bhardwaj Kanika, Dabas Garvita   +4 more
doaj   +1 more source

Long Term Glaucoma Drug Delivery Using a Topically Retained Gel/Microsphere Eye Drop

Scientific Reports, 2017
The purpose of this study was to characterize and determine the efficacy of a long-term, non-invasive gel/microsphere (GMS) eye drop for glaucoma. This novel drug delivery system is comprised of a thermoresponsive hydrogel carrier and drug-loaded polymer
Morgan V. Fedorchak, Ian P. Conner, Joel S. Schuman, Anthony Cugini, Steven R. Little   +4 more
doaj   +1 more source

Comparative Analysis of Pupil Diameters in Light and Dark Conditions After Instillation of 0.15% Brimonidine Drops in Eyes With and Without Pseudoexfoliation Syndrome

Beyoglu Eye Journal, 2020
INTRODUCTION[|] This study aimed to compare pupil diameters in light and dark conditions after instillation of 0.15% brimonidine drops in eyes with and without pseudoexfoliation syndrome (PES).[¤]METHODS[|]Forty eyes of 40 patients in whom 0.15 ...
Sercan Cate, Çağlar Bektaş, Burak Turgut   +2 more
doaj   +1 more source

Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Argon laser trabeculoplasty (ALT) is an intraocular pressure lowering method that is overall safe and powerful, but often complicated by transient postoperative intraocular pressure rises.
Božić Marija, Hentova-Senćanić Paraskeva, Kontić Đorđe, Marković Vujica, Marjanović Ivan   +4 more
doaj   +1 more source