Results 51 to 60 of about 8,176 (221)

Patient Factors Influencing Intraocular Penetration of Brimonidine-Related Eye Drops in Adults: A Post Hoc Pooled Analysis

Ophthalmology and Therapy, 2023
Introduction The factors related to the ocular penetration of drugs after the administration of eye drops in humans have not been examined in detail. Therefore, this study assessed the influence of patient factors on the intraocular penetration of eye ...
Eriko Kunikane, Yusuke Orii, Akiko Inoue, Masaru Inatani   +3 more
doaj   +1 more source

24-h Efficacy of Glaucoma Treatment Options [PDF]

, 2016
Current management of glaucoma entails the medical, laser, or surgical reduction of intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate with either stability or delayed progression of visual loss.
Banu, Bozkurt., Garcia-Feijoo, Julian, Katsanos, Andreas, Konstas, Anastasios, Miglior, Stefano, Pfeiffer, Norbert, Quaranta, Luciano, Rossetti, Luca, Shaarawy, Tarek   +8 more
core   +1 more source

Monitoring new long-lasting intravitreal formulation for glaucoma with vitreous images using optical coherence tomography [PDF]

, 2021
Intravitreal injection is the gold standard therapeutic option for posterior segment patholo-gies, and long-lasting release is necessary to avoid reinjections. There is no effective intravitreal treatment for glaucoma or other optic neuropathies in daily
Cardiel, M.J., Cegoñino, J., Fraile, J.M., Garcia-Martin, E., Martinez-Rincon, T., Mayoral, J.A., Mendez-Martinez, S., Montolío, A., Polo, V., Pérez Del Palomar, A., Rodrigo, M.J., Subias, M., Vispe, E.   +12 more
core   +1 more source

Comparisons of efficacy and safety between preserved and preservative-free brimonidine tartrate in glaucoma and ocular hypertension: a parallel-grouped, randomized trial

Scientific Reports, 2023
This multicenter (four institutions), randomized, investigator-masked, parallel-group clinical trial evaluated and compared the efficacy and safety of preservative-free and preserved brimonidine tartrate 0.15% in open-angle glaucoma and ocular ...
Ko Eun Kim, Chang Kyu Lee, Jonghoon Shin, Yuri Kim, Seungsoo Rho   +4 more
doaj   +1 more source

Brimonidine-Soluplus Nanomicelles: Preparation and in-vitro evaluation

Iraqi Journal of Pharmaceutical Sciences
Brimonidine is an active pharmaceutical ingredient used to treat glaucoma as a topical eye drop. Ophthalmic topical preparations are associated with low ocular bioavailability due to several physiological and analytical barriers.
Noor Al wiswasi, Fatima J. Al-Gawahri
doaj   +1 more source

Evaluation of brimonidine loaded DNA-nanoparticles [PDF]

, 2020
Nanopartikel (NP) stellen eine weitverbreitete Methode dar, um Behandlungen in der Medizin und Augenheilkunde zu verbessern. Dazu stehen verschiedenste Materialien zur Verfügung. Eine sehr elegante Möglichkeit ist die Verwendung von DNA. Vor kurzem wurde
Frößl, Katharina
core   +1 more source

Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

Ophthalmology and Therapy, 2019
Introduction Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues ...
Keisuke Shinno, Kazuya Kurokawa, Seiko Kozai, Akio Kawamura, Katsuhiro Inada, Hideki Tokushige   +5 more
doaj   +1 more source

Changes in visual function after intraocular pressure reduction using antiglaucoma medications [PDF]

, 2009
Purpose To evaluate the change in visual function after starting glaucoma treatment and correlate this to a decrease in intraocular pressure (IOP) in primary open-angle glaucoma patients.Methods A prospective, randomized clinical trial was carried out ...
A Harris, A Heijl, AS Hawkins, C Holmin, CS Tsai, D Regan, DW Evans, DW Evans, GN Pomerance, HA Quigley, J Flammer, JE Ross, JS Pointer, L A S Melo, LJ Katz, M V Piassi, O Arend, RN Weinreb, S Salim, SA Gandolfi, SA Gandolfi, T S Prata, WC Stewart   +22 more
core   +2 more sources

Comparative efficacy study of brimonidine tartrate 0.15% and timolol maleate 0.5% ophthalmic solution (benzalkonium chloride free) versus Brimolol® (with benzalkonium chloride) following single ocular instillation in New Zealand white rabbits [PDF]

, 2020
Background: Benzalkonium chloride (BKC) is the most used preservative in topical eye drops but it causes effects such as dry eye and trabecular meshwork degeneration.
Bhowmick, Subhas, Burade, Vinod, Chauhan, Sateesh Kumar, Thavkar, Amit   +3 more
core   +2 more sources

Comparative study of brimonidine and timolol in treatment of glaucoma

MRIMS Journal of Health Sciences, 2015
Background: As population is affected with primary open angle Glaucoma is large. It is important to evaluate drugs which effectively control the intraocular pressure.
Jagadish Chandrarao Narasaiah Lakkineni
doaj   +1 more source