Results 1 to 10 of about 1,912 (177)

Case Report: Carbonic anhydrase inhibitor brinzolamide dramatically improved the morphology and also function of a patient with RS1 mutation [PDF]

Frontiers in Pharmacology
X-linked retinoschisis (XLRS) is an inherited retinal disease caused by mutations in the RS1 gene, which encodes retinoschisin, a protein essential for maintaining the retinal structure during development.
Yue Ren, Yue Ren, Shu Liu, Shu Liu, Jia Rong, Di Wang, Miao Diao, Yaqi Zhang, Shimiao Tian, Mingxin Shang, Chuqiao Song, Yan Guan, Zhuoshi Wang, Zhuoshi Wang, Jijing Pang, Jijing Pang, Jijing Pang   +16 more
doaj   +2 more sources

Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2019
Background: Brinzolamide as a carbonic anhydrase inhibitor could be combined with other intraocular pressure (IOP) lowering drugs for glaucoma and ocular hypertension (OHT), but the efficacy was controversial.
Xiaoyan Zhong, Yuanzhi Liu, Qiming Wei   +2 more
exaly   +3 more sources

Co-delivery of brinzolamide and miRNA-124 by biodegradable nanoparticles as a strategy for glaucoma therapy

Drug Delivery, 2020
Co-delivery nanoparticles with characteristics of intracellular precision release drug have been generally accepted as an effective therapeutic strategy for eye diseases.
Xinrong Zhou
exaly   +2 more sources

Sustained intraocular pressure-lowering effect and biocompatibility of a single subconjunctival administration of hydrogel-encapsulated nano-brinzolamide [PDF]

Journal of Materials Science: Materials in Medicine
Brinzolamide is a widely used treatment for glaucoma, but its effectiveness relies on at least twice-daily dosing, which can be challenging for patient adherence.
Jiahao Xu, Linyu Long, Xiaoyu Zhou, Xinyue Zhang, Li Liao, Dan Ji, Xuanchu Duan   +6 more
doaj   +2 more sources

Effect of topical brinzolamide on visual function and waveform in patients of infantile nystagmus syndrome: A randomized control trial [PDF]

Indian Journal of Ophthalmology
Purpose: To evaluate the effect of topical carbonic anhydrase inhibitor (brinzolamide) versus placebo on visual function and waveforms in infantile nystagmus syndrome (INS). Design: Prospective, placebo-controlled, double-blind, cross-over study. Methods:
Bhupendra Yadav, Rohit Saxena, Rebika Dhiman, Kanwal P. Kochhar, Ashlesh Patil, Pradeep Sharma, Ramanjit Sihota, Radhika Tandon   +7 more
doaj   +2 more sources

Intraocular pressure is a promising target for myopia control [PDF]

Journal of Translational Medicine
Background Myopia presents a noteworthy global health concern, urging exploration of innovative treatments. The role of intraocular pressure (IOP) in regulating the progression of myopia has been controversial.
Peiyuan Wang, Kangjie Kong, Jiaxuan Jiang, Jingwen Jiang, Zihong Xie, Fengbin Lin, Yunhe Song, Xiuli Fang, Ling Jin, Fei Li, Wei Wang, Shaolin Du, Zhuoxing Shi, Junwen Zeng, Xiulan Zhang, Shida Chen, for the Glaucoma Suspects with High Myopia Study Group   +16 more
doaj   +2 more sources

Allergic Contact Dermatitis From Dorzolamide Without Cross-Reactivity to Brinzolamide. [PDF]

Contact Dermatitis
Contact Dermatitis, Volume 95, Issue 1, Page 116-117, July 2026.
Ghozli E, Leleu C, Arnould L, Collin L, Collet E.   +4 more
europepmc   +2 more sources

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018-2022). [PDF]

Vet Ophthalmol
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Sarfaty H, Ezra-Elia R, Kahane N, Sandalon S, Segev Y, Sebbag L.   +5 more
europepmc   +2 more sources

Twelve-Year Clinical Course of a Band-Shaped Remnant in the Anterior Chamber Following Trabeculotomy With the Trabectome. [PDF]

Clin Case Rep
Slit‐lamp and gonioscopic findings 4 months after Trabectome surgery. A band‐shaped remnant was observed in the inferonasal quadrant of the left eye, with continuity to the trabecular meshwork on gonioscopy. ABSTRACT Band‐shaped remnants in the anterior chamber after trabeculotomy with the Trabectome may not be associated with long‐term clinical ...
Takeuchi K, Takagi Y, Asano R.
europepmc   +2 more sources

Retrospective Assessment of Carbonic Anhydrase Inhibitors in Topical or Episcleral Implant Form for the Treatment of Equine Glaucoma. [PDF]

Vet Ophthalmol
ABSTRACT Objective To assess whether topical carbonic anhydrase inhibitors (CAIs) with or without episcleral brinzolamide implants control intraocular pressure (IOP) in horses with glaucoma. Animals Studied 12 client‐owned horses diagnosed with glaucoma.
Tucker-Retter EK, Yamagata M, Gilger B, Oh A.   +3 more
europepmc   +2 more sources