Results 1 to 10 of about 2,319 (150)

Effects of brinzolamide on rabbit ocular blood flow in vivo and ex vivo [PDF]

International Journal of Ophthalmology, 2018
AIM: To investigate if significant improvement of optic disc blood flow (ODBF) occurs after instillation of brinzolamide onto rabbit eyes. METHODS: Testing of bilateral intraocular pressure (IOP) and left ODBF in 10 male rabbits took place every 3h over
Ya-Ru Dong, Shi-Wei Huang, Ji-Zhe Cui, Takeshi Yoshitomi   +3 more
doaj   +2 more sources

Case Report: Carbonic anhydrase inhibitor brinzolamide dramatically improved the morphology and also function of a patient with RS1 mutation [PDF]

Frontiers in Pharmacology
X-linked retinoschisis (XLRS) is an inherited retinal disease caused by mutations in the RS1 gene, which encodes retinoschisin, a protein essential for maintaining the retinal structure during development.
Yue Ren, Yue Ren, Shu Liu, Shu Liu, Jia Rong, Di Wang, Miao Diao, Yaqi Zhang, Shimiao Tian, Mingxin Shang, Chuqiao Song, Yan Guan, Zhuoshi Wang, Zhuoshi Wang, Jijing Pang, Jijing Pang, Jijing Pang   +16 more
doaj   +2 more sources

Evaluation of the effect of brinzolamide 1% ophthalmic suspension on nystagmus using videonystagmography [PDF]

Indian Journal of Ophthalmology
Purpose: To evaluate the effect of topical brinzolamide (Azopt) eye drops on nystagmus using videonystagmography in infants and children. Methods: Setting: Institutional (Cairo University Hospitals). Study population: Both eyes of 40 patients, presenting
Rehab Rashad Kassem, Hussein Sherif Hamdy, Dina Hossameldin Hassanein, Randa Mohamed Abdel-Moneim El-Mofty   +3 more
doaj   +2 more sources

Co-delivery of brinzolamide and miRNA-124 by biodegradable nanoparticles as a strategy for glaucoma therapy

Drug Delivery, 2020
Co-delivery nanoparticles with characteristics of intracellular precision release drug have been generally accepted as an effective therapeutic strategy for eye diseases.
Xinrong Zhou
exaly   +2 more sources

Treatment Persistence with Combination Eye Drops for Glaucoma: A Longitudinal Analysis Using Japanese Medical Claims Data [PDF]

Ophthalmology and Therapy
Introduction Glaucoma is a chronic progressive disease and the leading cause of blindness, particularly among older individuals. Treatment persistence with intraocular pressure (IOP)-lowering therapy is essential to avoid visual impairment, although data
Kenji Kashiwagi, Miyuki Matsukawa, Rikiya Toda, Kana Okamoto, Daisaku Michikami   +4 more
doaj   +2 more sources

Sustained intraocular pressure-lowering effect and biocompatibility of a single subconjunctival administration of hydrogel-encapsulated nano-brinzolamide [PDF]

Journal of Materials Science: Materials in Medicine
Brinzolamide is a widely used treatment for glaucoma, but its effectiveness relies on at least twice-daily dosing, which can be challenging for patient adherence.
Jiahao Xu, Linyu Long, Xiaoyu Zhou, Xinyue Zhang, Li Liao, Dan Ji, Xuanchu Duan   +6 more
doaj   +2 more sources

Intraocular pressure is a promising target for myopia control [PDF]

Journal of Translational Medicine
Background Myopia presents a noteworthy global health concern, urging exploration of innovative treatments. The role of intraocular pressure (IOP) in regulating the progression of myopia has been controversial.
Peiyuan Wang, Kangjie Kong, Jiaxuan Jiang, Jingwen Jiang, Zihong Xie, Fengbin Lin, Yunhe Song, Xiuli Fang, Ling Jin, Fei Li, Wei Wang, Shaolin Du, Zhuoxing Shi, Junwen Zeng, Xiulan Zhang, Shida Chen, for the Glaucoma Suspects with High Myopia Study Group   +16 more
doaj   +2 more sources

Quantification of Carbonic Anhydrase Inhibitors and Metabolites in Urine and Hair of Patients and Their Relatives

Biology, 2022
Carbonic anhydrase inhibitors (CAIs) are prescription drugs also used in doping to dilute urine samples and tamper with urinalyses. Dorzolamide, brinzolamide, and acetazolamide are prohibited by the World Anti-Doping Agency.
Alfredo Fabrizio Lo Faro, Anastasio Tini, Giulia Bambagiotti, Filippo Pirani, Andrea Faragalli, Flavia Carle, Elena Pacella, Artan Ceka, Marco Moretti, Massimo Gottardi, Nicola Vito Lassandro, Michele Nicolai, Marco Lupidi, Cesare Mariotti, Francesco Paolo Busardò, Jeremy Carlier   +15 more
doaj   +1 more source

VALIDATED SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS DETERMINATION OF BRINZOLAMIDE AND TIMOLOL MALEATE IN THEIR PURE FORM AND OPHTHALMIC PREPARATION [PDF]

Al-Azhar Journal of Pharmaceutical Sciences, 2016
Four sensitive, simple and precise spectrophotometric methods for the simultaneous determination of brinzolamide (BRZ) and timolol maleate (TML) in their pharmaceutical formulation are developed and validated.
Maya Eissa
doaj   +1 more source

Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2019
Background: Brinzolamide as a carbonic anhydrase inhibitor could be combined with other intraocular pressure (IOP) lowering drugs for glaucoma and ocular hypertension (OHT), but the efficacy was controversial.
Yuanzhi Liu, Junyi Zhao, Junyi Zhao, Xiaoyan Zhong, Qiming Wei, Yilan Huang   +5 more
doaj   +1 more source