Results 91 to 100 of about 4,515 (264)
Representation learning of drug and disease terms for drug repositioning
, 2017 Drug repositioning (DR) refers to identification of novel indications for the approved drugs. The requirement of huge investment of time as well as money and risk of failure in clinical trials have led to surge in interest in drug repositioning.
Anand, Ashish, Manchanda, Sahil
core +1 more source
Interventions for central serous chorioretinopathy: a network meta-analysis. [PDF]
, 2015 BACKGROUND: Central serous chorioretinopathy (CSC) is characterized by serous detachment of the neural retina with dysfunction of the choroid and retinal pigment epithelium (RPE).
Evans, Jennifer R +4 more
core +1 more source
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT A shallow anterior chamber (AC) after glaucoma filtration surgery is a common early postoperative complication that can be vision‐threatening. So, early recognition of the causative factors and prompt management are necessary to avoid such devastating complications after surgery.
Md. Iftekher Iqbal, Fariah Osman
wiley +1 more source
Carbonic Anhydrase Inhibitors in the Treatment of Glaucoma. Review. Part I
Oftalʹmologiâ, 2020 Glaucoma is the main cause of irreversible blindness in the world. Carbonic anhydrase inhibitors (CAIS) used both systemically and topically, reduce intraocular pressure effectively.
N. I. Kurysheva
doaj +1 more source
Topical brinzolamide and metabolic acidosis [PDF]
British Journal of Ophthalmology, 2006 Treatment of ophthalmic disease largely involves the administration of topical medication in doses that would appear small relative to those used systemically. With a few exceptions (such as β receptor antagonists) the systemic side effects of topical ocular medication, though recognised, are often ignored in clinical practice.
G J Menon, S A Vernon
openaire +1 more source
The Use of Mucoadhesive Polymers to Enhance the Hypotensive Effect of a Melatonin Analogue, 5-MCA-NAT, in Rabbit Eyes [PDF]
, 2011 Purpose.: 5-Methoxy-carbonylamino-N-acetyltryptamine (5-MCA-NAT, a melatonin receptor agonist) produces a clear intraocular pressure (IOP) reduction in New Zealand White rabbits and glaucomatous monkeys. The goal of this study was to evaluate whether the
Andrés Guerrero, Vanessa +5 more
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Otolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li +2 more
wiley +1 more source
Analytical method development and validation for the determination of Brinzolamide by RP-HPLC [PDF]
, 2020 Brinzolamide is inhibitor of carbonic anhydride and is highly specific and non-competitive. The aim of the present study is to develop a simple, precise, accurate, sensitive RP-HPLC method for the determination of bulk drug.
Kulkarni, Amol +2 more
core +2 more sources
Frontiers in MaterialsMicroemulsions (μEs) are more effective than conventional formulations for ophthalmic use due to their optical transparency, thermodynamic stability, structural flexibility and higher bioavailability.
Sehrish Zafar +8 more
semanticscholar +1 more source
Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.Abstract Homozygous sauteur d'Alfort rabbits have a splicing‐site mutation in the RAR‐related orphan receptor B (RORB) gene that causes changes in their locomotion. These rabbits sometimes walk on their thoracic limbs, especially at higher speeds. They also experience additional abnormalities, including eye alterations such as blindness due to retinal ...
Kerstin Müller +4 more
wiley +1 more source