Results 71 to 80 of about 2,319 (150)

Brinzolamide loaded core-shell nanoparticles for enhanced coronial penetration in the treatment of glaucoma

Journal of Applied Biomaterials & Functional Materials, 2020
A neurodegenerative disorder, glaucoma is a leading cause of blindness in the world. The conventional treatment strategies do not allow the significant penetration of the drug in the cornea.
Jing Song, Ziping Zhang
doaj   +1 more source

Efficacy and safety of combination therapy with latanoprost after a change in therapeutic regimen from timolol to brinzolamide in Japanese adult patients with primary open-angle glaucoma and ocular hypertension: open, non-randomized 12-week study

Clinical Ophthalmology, 2008
Shusaku Ishikawa1, Yoshimi Nakamura1, Yuko Nakamura1, Hiroshi Sakai1, Shoichi Sawaguchi1, Kazuo Terashima2, Makoto Kanno2, Hidetoshi Yamashita21Department of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, Japan; 2Department of ...
Shusaku Ishikawa, Yoshimi Nakamura, Yuko Nakamura, Hiroshi Sakai, Shoichi Sawaguchi, et al   +5 more
doaj  

DataSheet_1_Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis.docx

, 2019
Background: Brinzolamide as a carbonic anhydrase inhibitor could be combined with other intraocular pressure (IOP) lowering drugs for glaucoma and ocular hypertension (OHT), but the efficacy was controversial.
Junyi Zhao (3167856), Yuanzhi Liu (6873326), Qiming Wei (6873329), Xiaoyan Zhong (2552017), Yilan Huang (6873332)   +4 more
core   +1 more source

Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses

, 2008
Reasons for performing study: Only few drugs with limited efficacy are available for topical treatment of equine glaucoma. Objective: To evaluate the effect of topical administration of 1% brinzolamide on intraocular pressure (IOP) in clinically normal ...
Burger, D, F. L. MATHEIS, Spiess, Bernhard M, A. RAMPAZZO, D. BURGER, B. M. SPIESS, M. ROOS, Germann, S E, Roos, Malgorzata, S. E. GERMANN, Matheis, F L, Rampazzo, A   +11 more
core   +1 more source

Efficacy and tolerability of brinzolamide/brimonidine suspension and prostaglandin analogs in patients previously treated with dorzolamide/timolol solution and prostaglandin analogs

Clinical Ophthalmology, 2016
Jonathan S Lo,1 Pierre M Pang,2 Samuel C Lo3 1John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, 2MD-Pacific Eye Surgery Center, Honolulu, Hawaii, 3MD-Laser and Eye Surgery Center, Honolulu, Hawaii, USA Objective: Fixed ...
Lo JS, Pang PM, Lo SC
doaj  

Whiter and Greener RP-HPLC Method for Simultaneous Determination of Dorzolamide, Brinzolamide, and Timolol Using Isopropanol as a Sustainable Organic Solvent in the Mobile Phase

Separations
A sustainable reversed-phase chromatographic method has been developed and validated for the simultaneous determination of three active pharmaceutical ingredients, dorzolamide, brinzolamide, and timolol, used to treat glaucoma.
Sami El Deeb, Khalid Abdelsamad, Maria Kristina Parr   +2 more
doaj   +1 more source

Brinzolamide/brimonidine fixed combination for open-angle glaucoma and ocular hypertension treatment: hypotensive efficacy and tolerability

Российский офтальмологический журнал
The literature review analyzes the data of 12-year clinical use of a fixed combination of 1% brinzolamide and 0.2 % brimonidine (BBFC) in the treatment of glaucoma and ocular hypertension.
S. Yu. Petrov, A. N. Zhuravleva, O. M. Filippova, A. V. Starostina, O. I. Markelova   +4 more
doaj   +1 more source

Brinzolamide 1%/timolol versus dorzolamide 2%/timolol in the treatment of open-angle glaucoma or ocular hypertension: prospective randomized patient-preference study

, 2015
Romeo Altafini,1 Maria-Luise Scherzer,2 Douglas A Hubatsch,3 Paolo Frezzotti4 1Glaucoma Segment Unit, “San Bortolo” Hospital, Vicenza, Italy; 2Private Practice, Regenstauf, Germany; 3Alcon Laboratories, Inc., Fort Worth, TX, USA; 4Ophthalmic
Scherzer ML, Frezzotti P, Hubatsch DA, Altafini R   +3 more
core  

Experience in Application of the Combinations Dorzolamide / Timolol and Brinzolamide / Timolol for the Prevention of Intraocular Hypertension in Patients with Silicone Oil Tamponade of the Vitreal Cavity

Oftalʹmologiâ
Purpose: to conduct a comparative analysis of the clinical efficacy of a fixed combination of antihypertensive drugs: brinzolamide 1 % = timolol 0.5 % and dorzolamide 2 % = timolol 0.5 % for the prevention of intraocular hypertension in patients with ...
A. N. Kazennov, A. D. Chuprov, I. A. Kazennova, A. S. Firsov   +3 more
doaj   +1 more source

Brinzolamide encapsulated β-cyclodextrin-chondroitin sulfate nanocomplexes anchored chitosan/polycaprolactone nanofibers as an ocular insert for glaucoma treatment

Materials Today Bio
Glaucoma ranked second among the causes of blindness globally, necessitates the development of novel and effective therapeutic strategy. Anti-glaucoma eye drops as a topical dosage form are still considered as a method of choice for glaucoma treatment ...
Haroon Iqbal, Dengming Zhou, Anam Razzaq, Haiyang Zhang, Run Xiao, Fu Lin, Yuanbo Liang   +6 more
doaj   +1 more source