Results 81 to 90 of about 3,304 (220)

A comparative study on efficacy of fixed combination timolol/brinzolamide versus travoprost monotherapy in drug-naïve open-angle glaucoma patients

Therapeutic Advances in Ophthalmology, 2020
Background: Glaucoma is most common irreversible cause of blindness in India. First line management of open-angle glaucoma is either beta blockers or prostaglandin analogs monotherapy.
Alok Dixit, Atul Ashish, Reena Sharma
doaj   +1 more source

Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations [PDF]

, 2015
Network-based methods are playing an increasingly important role in drug design. Our main question in this paper was whether the efficiency of drug target proteins to spread perturbations in the human interactome is larger if the binding drugs have side ...
A Banerjee, A Bauer-Mehren, A Franceschini, A Sharma, A Stojmirović, AF Fliri, C Knox, D Bray, D Brockmann, D Fazekas, D Parchwani, D Veres, DH Zanette, E Lounkine, H Hu, H Iwata, H Luo, HY Chuang, IW Taylor, J Serra-Musach, J Sun, J Wang, J Xia, JC Nacher, JL Oliveira, JM Schwartz, JO Rosado, KZ Szalay, KZ Szalay, L Brouwers, L Yang, L Yang, M Campillos, M Kuhn, M Takarabe, MA Antal, MA Yildirim, P Csermely, P Lopes, P Shannon, P Wang, PF Jonsson, R Nussinov, S Aral, S Lee, S Mizutani, SA Forbes, SP Cornelius, SP Wein, T Hase, TI Oprea, TW Valente, Y Yamanishi, Á Mihalik   +53 more
core   +4 more sources

Visual field testing and glaucoma drug prescribing patterns in Australia

Ophthalmic and Physiological Optics, Volume 45, Issue 5, Page 1228-1237, July 2025.
Abstract Purpose To examine glaucoma practice patterns in Australia, focusing on visual field test uptake and antiglaucoma drug prescribing by optometrists and ophthalmologists. Design A serial cross‐sectional study was conducted to describe visual field testing charges and compare them to changes in comprehensive eye examination charges, as well as to
Catherine L. Jan, Algis Vingrys, Randall S. Stafford, Mengtian Kang, Xianwen Shang, Wenyi Hu, Jiahao Liu, Sanil Joseph, Mingguang He   +8 more
wiley   +1 more source

Medical treatment of open-angle glaucoma. [PDF]

, 2012
Most guidelines that exist for the treatment of primary open-angle glaucoma (POAG) – such the National Institute for Health and Clinical Excellence (NICE) guidelines (page 47) – recommend medicine as initial therapy, though laser treatment may also play ...
Abdull, Mohammad, Kiage, Dan, Kyari, Fatima, Ogunro, Adunola   +3 more
core   +2 more sources

Synthesis of Novel Isoindolinones: Carbonic Anhydrase Inhibition Profiles, Antioxidant Potential, Antimicrobial Effect, Cytotoxicity and Anticancer Activity

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.
Highly effective one‐pot synthesis of novel isoindolinones Inhibitory, antioxidant, antimicrobial cytotoxicity, and anticancer potentials of synthesized novel isoindolinone derivatives were investigated. ABSTRACT An efficient one‐pot method has been developed for synthesizing novel isoindolinone derivatives from 2‐benzoylbenzoic acid using ...
Yusuf Serdar Yazıcıoğlu, Şeydanur Elmas, Zeynep Kılıç, Murat Çelik, Buket Bakan, Ufuk Atmaca, Songül Bayrak   +6 more
wiley   +1 more source

Brinzolamide loaded core-shell nanoparticles for enhanced coronial penetration in the treatment of glaucoma

Journal of Applied Biomaterials & Functional Materials, 2020
A neurodegenerative disorder, glaucoma is a leading cause of blindness in the world. The conventional treatment strategies do not allow the significant penetration of the drug in the cornea.
Jing Song, Ziping Zhang
doaj   +1 more source

Anticholinesterase and carbonic anhydrase inhibitory activities of natural carnosic acid derivatives: A comprehensive in vitro and in silico study

Archiv der Pharmazie, Volume 358, Issue 3, March 2025.
Carnosic acid derivatives were evaluated for their inhibitory activities against acetyl‐ and butyrylcholinesterases (AChE, BChE) and carbonic anhydrases (CAs). Rosmanol exhibited exceptional potency, surpassing tacrine and acetazolamide. Molecular docking, MM‐GBSA, and MD simulations confirmed strong binding and stability.
Zeynep Köksal, Halil Şenol
wiley   +1 more source

Efficacy, Tolerability and Adverse Effects of Triple Fixed Dose Combination Brimonidine–Brinzolamide–Timolol Ophthalmic Suspension in Primary Open Angle Glaucoma: A Retrospective Study

Delhi Journal of Ophthalmology
Purpose: To evaluate the efficacy and tolerability of recently introduced triple fixed dose combination (TFC) of brimonidine–brinzolamide–timolol (BBTFC) in patients with primary open angle glaucoma (POAG).
Hina Kounsar, Swati Singh, Harsh Kumar
doaj   +1 more source

Addition of a fixed combination of brinzolamide 1%/timolol 0.5% to prostaglandin monotherapy in patients with glaucoma or ocular hypertension

Clinical Ophthalmology, 2011
Katrin Lorenz1, Klaus Rosbach2, Andreas Matt3, Norbert Pfeiffer11University Medical Center, Johannes Gutenberg-Universität Mainz, Mainz, Germany; 2Private practice, Mainz, Germany; 3Private practice, Köln-Hohenhaus, GermanyBackground ...
Lorenz K, Rosbach K, Matt A, Pfeiffer N
doaj  

Experiencia de clase inversa [PDF]

, 2015
El uso de herramientas multimedia ofrece una serie de oportunidades de mejora del proceso de enseñanza-aprendizaje. El recurso de clase inversa se ha mostrado como una herramienta útil en el proceso de aprendizaje, que permite mejorar los resultados ...
Bellot Bernabé, Juan Lorenzo, Formigós Bolea, Juan Antonio, García Cabanes, María Cristina, López Rodríguez, Damián, Maneu, Victoria   +4 more
core