Results 81 to 90 of about 2,254 (197)

Brinzolamide-induced retinopathy in neonatal rat: an alternative animal model of retinal neovascularization

open access: yes, 2013
Проблема неоваскуляризації сітківки штовхає дослідників до пошуку нових підходів до моделювання,діагностики та лікування неоангіоґенезу. В роботі вівчався вплив бринзоламід-індукованого системного ацидозу на неоваскуляризацію сітківки новонароджених ...
Гапунин, И.Д.   +2 more
core   +1 more source

Analytical method development and validation for the determination of Brinzolamide by RP-HPLC

open access: yes, 2020
Brinzolamide is inhibitor of carbonic anhydride and is highly specific and non-competitive. The aim of the present study is to develop a simple, precise, accurate, sensitive RP-HPLC method for the determination of bulk drug.
Shirsat, Mrunal K.   +2 more
core   +1 more source

Brinzolamide-induced retinopathy in neonatal rats: an alternative animal model of retinal neovascularization

open access: yes, 2014
Background and Purpose: Neovascular retinal pathology is steel uncertain. Thus, there is great need to investigate new modeling, diagnostic and treatment technologies.
BILETSKA, P.V.   +5 more
core  

A novel ocular delivery of brinzolamide based on gellan gum: in vitro and in vivo evaluation

open access: yes, 2018
Jingfen Sun, Zhengshen Zhou Department of Ophthalmology, Ruijin Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: The aim of the study was to develop a sustained ocular ...
Sun J, Zhou Z
core  

Effects of 1% Topical Brinzolamide on Intraocular Pressure in Healthy Dogs

open access: yes, 2016
Background: Glaucoma is one of the most common causes of blindness in dogs, and is generally characterized by death of the retinal ganglion cells associated with a rapid loss of vision. Increased intraocular pressure (IOP) occurs in patients with primary
Paulo Roberto Spiller   +15 more
core   +1 more source

Ocular Hypotensive Effect and Safety of Brinzolamide Ophthalmic Solution in Open Angle Glaucoma Patients

open access: yes, 2009
Background and Purpose: Brinzolamide is a new topical carbonic anhydrase inhibitor for intraocular pressure (IOP) control. It has high inhibitory activity against human carbonic anhydrase II, which is the key isoenzyme regulating aqueous humor production.
王清泓;黃振宇;洪伯廷;謝瑞玟;陳裕芳   +1 more
core  

Effects of Topical Brinzolamide on Infantile Nystagmus Syndrome Waveforms- Eyedrops for Nystagmus

open access: yes, 2011
Recent advances in infantile nystagmus syndrome (INS) surgery have uncovered the therapeutic importance of proprioception. In this report, we test the hypothesis that the topical carbonic anhydrase inhibitor (CAI) brinzolamide (Azopt) has beneficial ...
Louis F. Dell\u27Osso, PhD; Richard W. Hertle, MD; R. John Leigh, MD; Jonathan B. Jacobs, PhD; Susan King, BS; Stacia Yaniglos, OD
core  

Brinzolamide/timolol fixed combination: a new ocular suspension for the treatment of open-angle glaucoma and ocular hypertension

open access: yes, 2009
For the treatment of open-angle glaucoma, the most frequent cause of irreversible visual loss, fixed combinations of different topical intraocular pressure (IOP) lowering molecules have gained an important role in recent years.
BOZKURT, BANU   +2 more
core   +1 more source

Combination of brinzolamide and brimonidine for glaucoma and ocular hypertension: critical appraisal and patient focus

open access: yesPatient Preference and Adherence, 2014
Quang H Nguyen Division of Ophthalmology, Scripps Clinic, La Jolla, CA, USA Abstract: Glaucoma is one of the leading causes of blindness and is characterized by optic nerve damage that results in visual field loss.
Nguyen QH
doaj  

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