Results 21 to 30 of about 1,511 (168)

Development and validation of a fast ultra-high-performance liquid chromatography tandem mass spectrometry method for determining carbonic anhydrase inhibitors and their metabolites in urine and hair [PDF]

open access: yes, 2021
A new, rapid, sensitive, and comprehensive ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) method for quantifying diuretics (acetazolamide, brinzolamide, dorzolamide, and their metabolites) in human urine and hair was ...
Alfredo Fabrizio Lo Faro   +6 more
core   +1 more source

The Efficacy, Safety, and Satisfaction Associated with Switching from Brinzolamide or Brimonidine to Brinzolamide/Brimonidine in Open-Angle Glaucoma Patients

open access: yesJournal of Personalized Medicine, 2022
We evaluated switching from brinzolamide 1% or brimonidine 0.1% to a fixed-combination of brinzolamide 1% and brimonidine 0.1%, and then determined the efficacy, safety, and satisfaction associated with these changes in glaucoma patients. This prospective, nonrandomized study evaluated a total of 31 enrolled glaucoma patients who underwent treatment ...
Hiromitsu Onoe   +7 more
openaire   +2 more sources

Comparative study to assess efficacy and safety of brinzolamide1% and timolol0.5% fixed combination eye drops versus dorzolamide2% and timolol0.5% fixed combination eye drops in management of open-angle glaucoma

open access: yesJournal of Family Medicine and Primary Care, 2022
Aim and Objective: To compare the efficacy and safety of brinzolamide1% and timolol0.5% fixed combination eye drops versus dorzolamide2% and timolol0.5% fixed combination eye drops in the treatment of primary open-angle glaucoma.
Prerana Agarwal   +2 more
doaj   +1 more source

Adjunctive antihypertensive therapy of primary glaucoma with a fixed combination drug of 1% brinzolamide and 0.5% timolol: efficacy and safety

open access: yesРоссийский офтальмологический журнал, 2023
Purpose: a comparative study of the efficacy and safety of the combination drug Brinzopt Plus and the original drug Azarga used as adjunctive therapy in patients with primary open-angle glaucoma (POAG) previously treated with latanoprost.Material and ...
S. Yu. Petrov   +7 more
doaj   +1 more source

Analytical method development and validation for the determination of Brinzolamide by RP-HPLC [PDF]

open access: yes, 2020
Brinzolamide is inhibitor of carbonic anhydride and is highly specific and non-competitive. The aim of the present study is to develop a simple, precise, accurate, sensitive RP-HPLC method for the determination of bulk drug.
Kulkarni, Amol   +2 more
core   +2 more sources

Brinzolamide induced reversible corneal decompensation [PDF]

open access: yesBritish Journal of Ophthalmology, 2005
Topical carbonic anhydrase inhibitors (CAIs) such as brinzolamide 1% (Azopt; Alcon Laboratories, Fort Worth, TX, USA) attenuate bicarbonate efflux, and this may lead to corneal oedema. To our knowledge, this is the first report of complete resolution of corneal oedema after cessation of topical brinzolamide 1%. A 57 year old African-American man with
T Chen, J C Zhao
openaire   +2 more sources

Two Stability Indicating Chromatographic Methods: TLC Densitometric versus HPLC Method for the Simultaneous Determination of Brinzolamide and Timolol Maleate in Ophthalmic Formulation in the Presence of Probable Carcinogenic Oxidative Degradation Product of Timolol Maleate

open access: yesSeparations, 2023
A comparative study between two stability-indicating chromatographic methods for the assay of brinzolamide and timolol maleate in the co-existence of the probable carcinogenic oxidative degradation product of timolol maleate in their ophthalmic ...
Asmaa A. Mandour   +4 more
doaj   +1 more source

Assessing the safety and efficacy of switching to brinzolamide/timolol fixed combination as a replacement therapy in patients with uncontrolled intraocular pressure in Taiwan [PDF]

open access: yes, 2012
PurposeThe objective of this study is to assess the safety and efficacy of switching to brinzolamide 1% and timolol 0.5% fixed combination (BTFC) from prior pharmacotherapy in patients with open-angle glaucoma (OAG) or ocular hypertension (OH) in Taiwan ...
Chen, Ying-Ying   +2 more
core   +1 more source

Pharmaceutical treatment of primary open angle glaucoma [PDF]

open access: yes, 2021
Background: Glaucoma is a progressive, irreversible optic neuropathy that results in serious vision loss and blindness. This review aimed to summarize key concepts of primary open angle glaucoma (POAG) pharmaceutical treatment trials over the last decade.
Al-Namaeh , Mashael
core   +2 more sources

Efficacy of Topical Brinzolamide Treatment in Posterior Microphthalmos- Related Macular Cystoid Lesions: A Case Series

open access: yesTürk Oftalmoloji Dergisi, 2020
The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of
Ceren Durmaz Engin   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy