Results 21 to 30 of about 4,515 (264)

A comparative study on efficacy of fixed combination timolol/brinzolamide versus travoprost monotherapy in drug-naïve open-angle glaucoma patients [PDF]

Therapeutic Advances in Ophthalmology, 2020
Background: Glaucoma is most common irreversible cause of blindness in India. First line management of open-angle glaucoma is either beta blockers or prostaglandin analogs monotherapy.
Alok Dixit, Atul Ashish, Reena Sharma
doaj   +2 more sources

Efficacy and Safety of a Fixed-Dose Combination of Brinzolamide 1%/Timolol 0.5% vs. Dorzolamide 2%/Timolol 0.5% in Indian Patients With Primary Open-Angle Glaucoma or Ocular Hypertension: A Randomized Phase 3 Study. [PDF]

Cureus
Introduction Fixed-dose combinations (FDCs) have the potential in glaucoma management to improve efficacy due to the complementary mechanism of action of the drugs as well as compliance while reducing adverse effects by minimizing exposure to ...
Bhagat P, Singhania M, Navare S, Mazumdar M, Paul C, Shet S, Vks K, Nicholsan A, Bansal N, Jain P.   +9 more
europepmc   +2 more sources

Patient perspectives when switching from Cosopt® (dorzolamide-timolol) to Azarga™ (brinzolamide-timolol) for glaucoma requiring multiple drug therapy

Clinical Ophthalmology, 2012
Graham Anthony Auger, Mathew Raynor, Simon LongstaffOphthalmology Department, Royal Hallamshire Hospital, Sheffield, South Yorkshire, United KingdomBackground: This study aimed to determine the impact of switching patients requiring multiple drug ...
Auger GA, Raynor M, Longstaff S
doaj   +3 more sources

Brinzolamide induced reversible corneal decompensation [PDF]

British Journal of Ophthalmology, 2005
Topical carbonic anhydrase inhibitors (CAIs) such as brinzolamide 1% (Azopt; Alcon Laboratories, Fort Worth, TX, USA) attenuate bicarbonate efflux, and this may lead to corneal oedema. To our knowledge, this is the first report of complete resolution of corneal oedema after cessation of topical brinzolamide 1%. A 57 year old African-American man with
Jingxia Zhao
openaire   +3 more sources

Efficacy, Tolerability and Adverse Effects of Triple Fixed Dose Combination Brimonidine–Brinzolamide–Timolol Ophthalmic Suspension in Primary Open Angle Glaucoma: A Retrospective Study

Delhi Journal of Ophthalmology
Purpose: To evaluate the efficacy and tolerability of recently introduced triple fixed dose combination (TFC) of brimonidine–brinzolamide–timolol (BBTFC) in patients with primary open angle glaucoma (POAG).
Hina Kounsar, Swati Singh, Harsh Kumar
doaj   +2 more sources

Whiter and Greener RP-HPLC Method for Simultaneous Determination of Dorzolamide, Brinzolamide, and Timolol Using Isopropanol as a Sustainable Organic Solvent in the Mobile Phase

Separations
A sustainable reversed-phase chromatographic method has been developed and validated for the simultaneous determination of three active pharmaceutical ingredients, dorzolamide, brinzolamide, and timolol, used to treat glaucoma.
Sami El Deeb, Khalid Abdelsamad, Maria Kristina Parr   +2 more
doaj   +2 more sources

Brinzolamide loaded core-shell nanoparticles for enhanced coronial penetration in the treatment of glaucoma

Journal of Applied Biomaterials & Functional Materials, 2020
A neurodegenerative disorder, glaucoma is a leading cause of blindness in the world. The conventional treatment strategies do not allow the significant penetration of the drug in the cornea.
Jing Song, Ziping Zhang
doaj   +2 more sources

Intraocular pressure is a promising target for myopia control [PDF]

Journal of Translational Medicine
Background Myopia presents a noteworthy global health concern, urging exploration of innovative treatments. The role of intraocular pressure (IOP) in regulating the progression of myopia has been controversial.
Peiyuan Wang, Kangjie Kong, Jiaxuan Jiang, Jingwen Jiang, Zihong Xie, Fengbin Lin, Yunhe Song, Xiuli Fang, Ling Jin, Fei Li, Wei Wang, Shaolin Du, Zhuoxing Shi, Junwen Zeng, Xiulan Zhang, Shida Chen, for the Glaucoma Suspects with High Myopia Study Group   +16 more
doaj   +2 more sources

Effects of brinzolamide vs timolol as an adjunctive medication to latanoprost on circadian intraocular pressure control in primary open-angle glaucoma Japanese patients [PDF]

Clinical Ophthalmology, 2009
Makoto Ishikawa1,2, Takeshi Yoshitomi11Department of Ophthalmology, Akita University Faculty of Medicine, Akita, Japan; 2Department of Ophthalmology, Ogachi Central Hospital, Akita, JapanPurpose: To study the effect of the concomitant use of brinzolamide
Makoto Ishikawa, Takeshi Yoshitomi
doaj   +3 more sources

Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension [Erratum]

Clinical Ophthalmology, 2014
 Yoshikawa K, Kozaki J, Maeda H. Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension. Clin Ophthalmol.
Yoshikawa K, Kozaki J, Maeda H
doaj   +3 more sources