Results 81 to 90 of about 4,515 (264)

Comparison of the Effects of Timolol, Brinzolamide, Brimonidine and Netarsudil in a Rabbit Model of Water Loading-Induced Ocular Hypertension

Current Eye Research
Purpose This study aimed to compare the intraocular pressure (IOP)-lowering effects of timolol (a β-blocker), brinzolamide (a carbonic anhydrase inhibitor), brimonidine (an α2-agonist) and netarsudil (a rho kinase inhibitor) in rabbits.
Junya Maruoka, Y. Takeji, Daisuke Yamashita, Keisuke Hino, Shinsaku Itoh, Yusuke Kakumoto, Kazushi Sakurai, Hiroki Urashima   +7 more
semanticscholar   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Nanoliposome-Encapsulated Brinzolamide-hydropropyl-β-cyclodextrin Inclusion Complex: A Potential Therapeutic Ocular Drug-Delivery System

Frontiers in Pharmacology, 2018
Novel ocular drug delivery systems (NODDSs) remain to be explored to overcome the anatomical and physiological barriers of the eyes. This study was to encapsulate brinzolamide (BRZ)-hydropropyl-β-cyclodextrin (HP-β-CD) inclusion complex (HP-β-CD/BRZ ...
Fazhan Wang, Xingting Bao, Aiping Fang, Aiping Fang, Huili Li, Yang Zhou, Yongmei Liu, Chunling Jiang, Jinhui Wu, Xiangrong Song   +9 more
doaj   +1 more source

Efficacy of Brinzolamide in the Initial Management of Acute Primary Angle Closure in Chinese: a Randomized Controlled Trial [PDF]

, 2021
Guang Chen, Xinming Peng, Jun Li, Peng Chen, Jing Wang   +4 more
openalex   +1 more source

Suprachoroidal Hemorrhage with Delayed Rebleeding as the First Presentation of Bullous Pemphigoid Associated Acquired Hemophilia [PDF]

, 2016
published_or_final_versio
Choy, NKB, Lai, JSM, Mak, KHA, Ng, LKA, Shum, JWH   +4 more
core   +1 more source

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

Veterinary Ophthalmology, Volume 28, Issue 6, Page 917-925, November 2025.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim, Young‐Sun Kang, Joon Young Kim   +2 more
wiley   +1 more source

Patient Factors Influencing Intraocular Penetration of Brimonidine-Related Eye Drops in Adults: A Post Hoc Pooled Analysis

Ophthalmology and Therapy, 2023
Introduction The factors related to the ocular penetration of drugs after the administration of eye drops in humans have not been examined in detail. Therefore, this study assessed the influence of patient factors on the intraocular penetration of eye ...
Eriko Kunikane, Yusuke Orii, Akiko Inoue, Masaru Inatani   +3 more
doaj   +1 more source

Penetration enhancers in ocular drug delivery [PDF]

, 2019
There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science.
Abdulrazik, Afouna, Afouna, Agarwal, Albert, Bowling, Caretti, Chordiya, Chung, Denniston, Geerling, González de Llano, Grass, Hodges, Jackson, Jampilek, Kaur, Kefalov, Khutoryanskiy, , Lang, Lisch, Moiseev, , Montenegro, Morrison, Morrison, , Murphy, Nag, Pedersen, Quigley, Schachat, Schlote, Sebag, Smith, Steele, , Stefánsson, Sundaram, Tsai, Washington, Yanoff   +38 more
core   +1 more source

Co-delivery of brinzolamide and miRNA-124 by biodegradable nanoparticles as a strategy for glaucoma therapy

Drug Delivery, 2020
Co-delivery nanoparticles with characteristics of intracellular precision release drug have been generally accepted as an effective therapeutic strategy for eye diseases.
Tingting Li, Ye Wang, Jiahao Chen, Xiaoshu Gao, Siqi Pan, Yu Su, Xinrong Zhou   +6 more
doaj   +1 more source

ANIDRASI CARBONICA:SINTESI DI SOLFONAMMIDI BENZOTIOPIRANO-PIRIMIDINICHE QUALI POTENZIALI INIBITORI ISOFORMA SELETTIVI [PDF]

, 2015
Le anidrasi carboniche (CA) sono una superfamiglia di metallo-enzimi che catalizzano l’interconversione tra anidride carbonica e ione bicarbonato. Ad oggi sono conosciute cinque distinte famiglie genetiche di diversa evoluzione: α-CA, β-CA, γ-CA, δ-CA e ...
PESCAGLINI, SARA
core