Results 111 to 120 of about 16,667 (304)

Bristle: A Mobile Structured Peer-to-Peer Architecture,

open access: yes, 2003
[[abstract]]Most hash-based structured peer-to-peer (HS-P2P) architectures proposed previously focus on stationary peer nodes. When peers move to new locations in the network, these schemes become cumbersome and inefficient in delivering messages.
Hsiao,H.C., King,C.T.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Yellow bristle grass

open access: yes, 2016
Content of presentation: • Yellow bristle grass and similar species • Why are we so worried about it? • How and where does it grow? • What can we do about it?
Trevor James (15393830)
core  

A 2D Bristle Friction Force Model for Contact Dynamics Simulation

open access: yes, 2009
This paper describes a 2D bristle contact friction model which is capable of modeling and simulating frictional behavior in both sliding and sticking regimes occurring in general 3D rigid-body contact. The model extends the 1D integrated bristle friction
Ou Ma, Steven Fillmore, Jianxun Liang
core   +1 more source

Motility of a Model Bristle-Bot: a Theoretical Analysis. [PDF]

open access: yes, 2014
Bristle-bots are legged robots that can be easily made out of a toothbrush head and a small vibrating engine. Despite their simple appearance, the mechanism enabling them to propel themselves by exploiting friction with the substrate is far from ...
DeSimone, Antonio, Cicconofri, Giancarlo
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Lava-lamp is not required for Golgi organization in the bristle shaft.

open access: yes, 2019
Scanning electron microscope images (A-B') of adult bristles from A–Wild type, A’–higher magnification image of the tip area showing characteristic parallel grooved surface morphology; B–neur-Gal4::UAS-LVADN fly bristle, B’—higher magnification image of ...
Anna Melkov (3173280)   +4 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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