Results 31 to 40 of about 2,236,355 (176)

The S-PLUS Fifth Data Release: Over 4500 Square Degrees of the Southern Sky and a Multicolor View of the Hydra and Antlia Galaxy Clusters

open access: yesThe Astrophysical Journal
We present the fifth data release (DR5) of the Southern Photometric Local Universe Survey (S-PLUS), covering 4592 deg ^2 across 2491 fields. Observations were conducted with the T80-South, a Brazilian robotic telescope equipped with the Javalambre 12 ...
Erik Vinicius Rodrigues de Lima   +58 more
doaj   +1 more source

Phase Curves of Kuiper Belt Objects, Centaurs, and Jupiter-family Comets from the ATLAS Survey

open access: yesThe Planetary Science Journal, 2023
The Kuiper Belt objects (KBOs), the Centaurs, and the Jupiter-family comets (JFCs) form an evolutionary continuum of small outer solar system objects, and their study allows us to gain insight into the history and evolution of the solar system. Broadband
Matthew M. Dobson   +11 more
doaj   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

open access: yesAdvanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang   +15 more
wiley   +1 more source

CEERS Key Paper. IV. A Triality in the Nature of HST-dark Galaxies

open access: yesThe Astrophysical Journal Letters, 2023
The new capabilities that JWST offers in the near- and mid-infrared (IR) are used to investigate in unprecedented detail the nature of optical/near-IR-faint, mid-IR-bright sources, with HST-dark galaxies among them.
Pablo G. Pérez-González   +54 more
doaj   +1 more source

Latitude-dependent Atmospheric Waves and Long-period Modulations in Luhman 16 B from the Longest Light Curve of an Extrasolar World

open access: yesThe Astrophysical Journal
In this work, we present the longest photometric monitoring of up to 1200 hr of the strongly variable brown dwarf binaries Luhman 16 AB and provide evidence of ±5% variability on a timescale of several to hundreds of hours for this object.
Nguyen Fuda   +5 more
doaj   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng   +15 more
wiley   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

open access: yesAdvanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou   +3 more
wiley   +1 more source

SNR 1987A: Spitzer Data from Days 6000 to 8000 Revisited

open access: yesThe Astrophysical Journal
An excess emission has been observed by Spitzer in the 3–5 μ m range of the SNR 1987A spectrum. It is generally argued that this excess could be due to the presence of warm amorphous carbon dust in the equatorial ring around the supernova, but the ...
Patrice Bouchet   +3 more
doaj   +1 more source

Observations of Hot-Jupiter occultations combining Spitzer and Kepler photometry

open access: yesEPJ Web of Conferences, 2011
We present the status of an ongoing program which aim at measuring occultations by their parent stars of transiting hot giant exoplanets discovered recently by Kepler. The observations are obtained in the near infrared with WarmSpitzer Space Telescope
Knutson H.   +6 more
doaj   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan   +12 more
wiley   +1 more source

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