Results 51 to 60 of about 2,236,355 (176)

A Search for Late-type Brown Dwarfs in the Euclid Quick Data Release 1

open access: yesThe Astronomical Journal
We present the identification and characterization of 15 mid-to-late T dwarf candidates in the Euclid Quick Release 1 (Q1) data set, based on a combined photometric and spectroscopic analysis.
Frank Kiwy   +9 more
doaj   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

open access: yesThe FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan   +19 more
wiley   +1 more source

AGN STORM 2. XII. Ground-based Optical Photometry and Lag Measurements of Mrk 817

open access: yesThe Astrophysical Journal
We present the ground-based imaging campaign and light curves of Markarian 817 as part of the multiwavelength monitoring program AGN STORM 2. Observations were carried out over 1.4 yr in the uBgVriz filters, with a median cadence of 0.4 day in the g band.
John W. Montano   +46 more
doaj   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

open access: yesThe FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli   +6 more
wiley   +1 more source

BMAL1 in Anterior Cingulate Cortex Pyramidal Neurons Relieves Pulpitis‐Induced Nocturnal Pain

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Nocturnal exacerbation of pulpitis‐induced pain severely disrupts patients' sleep and quality of life, increasing emergency dental care burden. However, the exact mechanisms underlying nocturnal pain remain poorly understood, limiting the development of targeted analgesic strategies.
Yuting Bai   +8 more
wiley   +1 more source

The Pre-perihelion Evolution of the Activity of Comet C/2017 K2 (Pan-STARRS) during the Water Ice-line Crossover

open access: yesThe Astronomical Journal
Comets, relics from the early solar system, consist of dust and ice. The ice sublimates as comets approach the Sun, ejecting dust from their nuclei seen as activity.
Yuna G. Kwon   +6 more
doaj   +1 more source

Deletion of the sodium leak channel NALCN in dopamine neurons alters D2R‐mediated signalling and psychostimulant responsiveness

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The sodium leak channel NALCN is an important contributor to the spontaneous pacemaker activity of midbrain dopamine neurons and is required for proper presynaptic D2 autoreceptor signalling at dopaminergic terminals. Conditional deletion of NALCN in dopamine neurons enhances psychomotor sensitization to amphetamine and cocaine ...
Angelina Rogliardo   +16 more
wiley   +1 more source

The Discovery of the Faintest Known Milky Way Satellite Using UNIONS

open access: yesThe Astrophysical Journal
We present the discovery of Ursa Major III/UNIONS 1, the least luminous known satellite of the Milky Way, which is estimated to have an absolute V -band magnitude of $+{2.2}_{-0.3}^{+0.4}$ mag, equivalent to a total stellar mass of ${16}_{-5}^{+6}$ M _⊙ .
Simon E. T. Smith   +16 more
doaj   +1 more source

Optimizing Fertilization in Double‐Rice Systems: Balancing Grain Yield, Soil Organic Carbon and Greenhouse Gas Emissions

open access: yesJournal of Agronomy and Crop Science, Volume 212, Issue 6, November 2026.
Schematic diagram of yield enhancement, soil carbon sequestration and greenhouse gas mitigation under optimized fertilization regimes in double‐rice systems in the middle and lower reaches of the Yangtze River. ABSTRACT Addressing the urgent need to balance high yields with environmental sustainability in the Yangtze River's double‐rice systems, this ...
Chaoming Ma   +14 more
wiley   +1 more source

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