Results 51 to 60 of about 2,236,355 (176)
A Search for Late-type Brown Dwarfs in the Euclid Quick Data Release 1
We present the identification and characterization of 15 mid-to-late T dwarf candidates in the Euclid Quick Release 1 (Q1) data set, based on a combined photometric and spectroscopic analysis.
Frank Kiwy +9 more
doaj +1 more source
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
AGN STORM 2. XII. Ground-based Optical Photometry and Lag Measurements of Mrk 817
We present the ground-based imaging campaign and light curves of Markarian 817 as part of the multiwavelength monitoring program AGN STORM 2. Observations were carried out over 1.4 yr in the uBgVriz filters, with a median cadence of 0.4 day in the g band.
John W. Montano +46 more
doaj +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
BMAL1 in Anterior Cingulate Cortex Pyramidal Neurons Relieves Pulpitis‐Induced Nocturnal Pain
ABSTRACT Aim Nocturnal exacerbation of pulpitis‐induced pain severely disrupts patients' sleep and quality of life, increasing emergency dental care burden. However, the exact mechanisms underlying nocturnal pain remain poorly understood, limiting the development of targeted analgesic strategies.
Yuting Bai +8 more
wiley +1 more source
Comets, relics from the early solar system, consist of dust and ice. The ice sublimates as comets approach the Sun, ejecting dust from their nuclei seen as activity.
Yuna G. Kwon +6 more
doaj +1 more source
Abstract figure legend The sodium leak channel NALCN is an important contributor to the spontaneous pacemaker activity of midbrain dopamine neurons and is required for proper presynaptic D2 autoreceptor signalling at dopaminergic terminals. Conditional deletion of NALCN in dopamine neurons enhances psychomotor sensitization to amphetamine and cocaine ...
Angelina Rogliardo +16 more
wiley +1 more source
The Discovery of the Faintest Known Milky Way Satellite Using UNIONS
We present the discovery of Ursa Major III/UNIONS 1, the least luminous known satellite of the Milky Way, which is estimated to have an absolute V -band magnitude of $+{2.2}_{-0.3}^{+0.4}$ mag, equivalent to a total stellar mass of ${16}_{-5}^{+6}$ M _⊙ .
Simon E. T. Smith +16 more
doaj +1 more source
Schematic diagram of yield enhancement, soil carbon sequestration and greenhouse gas mitigation under optimized fertilization regimes in double‐rice systems in the middle and lower reaches of the Yangtze River. ABSTRACT Addressing the urgent need to balance high yields with environmental sustainability in the Yangtze River's double‐rice systems, this ...
Chaoming Ma +14 more
wiley +1 more source

