Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders. [PDF]
, 2019 Identification of genetic biomarkers associated with autism spectrum disorders (ASDs) could improve recurrence prediction for families with a child with ASD.
Brian, J +21 more
core +2 more sources
The broader autism phenotype and its implications on the etiology and treatment of autism spectrum disorders. [PDF]
Autism Res Treat, 2011 The presence of autism-related traits has been well documented in undiagnosed family members of individuals with autism spectrum disorder (ASD). The most common finding is mild impairments in social and communication skills that are similar to those shown by individuals with autism, but exhibited to a lesser degree.
Gerdts J, Bernier R.
europepmc +4 more sources
Visual attention in autism families: ‘unaffected’ sibs share atypical frontal activation [PDF]
, 2009 Background: In addition to their more clinically evident abnormalities of social cognition, people with autism spectrum conditions (ASC) manifest perturbations of attention and sensory perception which may offer insights into the underlying neural ...
Baron-Cohen, S, Belmonte, MK, Gomot, M
core +1 more source
The broader language phenotype of autism: a comparison with specific language impairment [PDF]
Journal of Child Psychology and Psychiatry, 2007 Background: Some individuals with autism spectrum disorders (ASD) experience linguistic difficulties similar to those found in individuals with specific language impairment (SLI). Whether these behaviours are indicative of a common underlying genetic cause or a superficial similarity is unclear.
Whitehouse, A., Barry, J., Bishop, D.
openaire +4 more sources
A Unifying Theory for Autism: The Pathogenetic Triad as a Theoretical Framework
Frontiers in Psychiatry, 2021 This paper presents a unifying theory for autism by applying the framework of a pathogenetic triad to the scientific literature. It proposes a deconstruction of autism into three contributing features (an autistic personality dimension, cognitive ...
Darko Sarovic +2 more
doaj +1 more source
Environmental and genetic influences on neurocognitive development: the importance of multiple methodologies and time-dependent intervention [PDF]
, 2014 Genetic mutations and environmental factors dynamically influence gene expression and developmental trajectories at the neural, cognitive, and behavioral levels.
Bryson S. E. +7 more
core +2 more sources
The expression and assessment of emotions and internal states in individuals with severe or profound intellectual disabilities [PDF]
, 2011 The expression of emotions and internal states by individuals with severe or profound intellectual disabilities is a comparatively under-researched area. Comprehensive or standardised methods of assessing or understanding the emotions and internal states
Adams, Dawn, Christopher, Oliver
core +1 more source
Development of neural responses to hearing their own name in infants at low and high risk for autism spectrum disorder [PDF]
, 2020 The own name is a salient stimulus, used by others to initiate social interaction. Typically developing infants orient towards the sound of their own name and exhibit enhanced event-related potentials (ERP) at 5 months. The lack of orientation to the own
Arslan, Melda +5 more
core +2 more sources
Prenatal Neurogenesis in Autism Spectrum Disorders. [PDF]
, 2016 An ever-increasing body of literature describes compelling evidence that a subset of young children on the autism spectrum show abnormal cerebral growth trajectories.
Kaushik, Gaurav +1 more
core +1 more source
Narrowing the broader autism phenotype [PDF]
Autism, 2010 This study investigated whether the Communication Checklist — Adult (CC-A) could identify subtypes of social and communication dysfunction in autism probands and their parents. The CC-A is divided into subscales measuring linguistic ability as well as two aspects of social communication: the Pragmatic Skills subscale assesses the level of pragmatic ...
Whitehouse, A +4 more
openaire +2 more sources