Results 61 to 70 of about 24,165 (274)

Defining the broader, medium and narrow autism phenotype among parents using the Autism Spectrum Quotient (AQ)

Molecular Autism, 2010
Background The Autism Spectrum Quotient (AQ) is a self-report questionnaire for quantifying autistic traits. This study tests whether the AQ can differentiate between parents of children with an autism spectrum condition (ASC) and control parents.
Wheelwright Sally, Auyeung Bonnie, Allison Carrie, Baron-Cohen Simon   +3 more
doaj   +1 more source

The autism spectrum as a source of cognitive and cultural diversity [PDF]

, 2011
Individual differences in perception and in social cognition are products of both biology and cultural experience. Many of the same differences that typify autism when they occur in extremes also underlie normal human cognitive variation when they occur ...
Belmonte, MK
core  

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

A transdiagnostic approach to neurodiversity in a representative population sample: The N+ 4 model

JCPP Advances
Background The concept of neurodiversity draws upon scientific research, and lessons from practice and lived experience to suggest new ways of thinking about neurodevelopmental conditions.
Ian A. Apperly, Robert Lee, Sanne W. van derKleij, Rory T. Devine   +3 more
doaj   +1 more source

Do adults with high functioning autism or Asperger Syndrome differ in empathy and emotion recognition? [PDF]

, 2016
The present study examined whether adults with high functioning autism (HFA) showed greater difficulties in (i) their self-reported ability to empathise with others and/or (ii) their ability to read mental states in others’ eyes than adults with Asperger
A Palmen, A Realo, A Spek, AM Daniels, AM Scheeren, AN Witwer, B Auyeung, C Allison, C Lord, C Lord, Carrie Allison, CE Wilson, Charlotte B. Montgomery, D Premack, DG Amaral, DL Williams, E Sucksmith, EJ Lawrence, FR Volkmar, GM McAlonan, J Cohen, J Mansell, J Paynter, J Treur, JC Raven, JL Barnes, JL Matson, K Gotham, KK Yu, L Pina-Camacho, L Wing, LY Tsai, M Ghaziuddin, M Ghaziuddin, M Mazza, M Serafin, M Vellante, M-C Lai, MC Tobin, Meng-Chuan Lai, MV Lombardo, N Kaland, P Fonagy, P Howlin, P Howlin, P Planche, Peter E. Langdon, R Bedford, RA Fabio, RA Richell, RJ Holt, RL Schalock, RT Schultz, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Baron-Cohen, S Cassidy, S Dehning, S Ozonoff, S Ozonoff, S Wheelwright, Sarah Cassidy, Simon Baron-Cohen, SJ Rogers, SR McConnell, TR Goldstein, U Hess, WB Groen, World Health Organization (WHO)   +73 more
core   +2 more sources

Emotion processing and the broader autism phenotype [PDF]

, 2018
The processing of emotion is fundamental in various aspects of human experience. However, our understanding of emotional processes is incomplete, particularly in relation to language processing. Further, individuals such as those with an autism spectrum disorder (ASD) often show differences in their perception and understanding of emotion.
openaire   +3 more sources

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

The Broad Autism (Endo)Phenotype: Neurostructural And Neurofunctional Correlates In Parents Of Individuals With Autism Spectrum Disorders

Frontiers in Neuroscience, 2016
Autism Spectrum Disorders (ASD) are a set of neurodevelopmental disorders with an early-onset and a strong genetic component in their pathogenesis. According to genetic and epidemiological data, ASD relatives present personality traits similar to, but ...
Lucia Billeci, Sara Calderoni, Eugenia Conti, Eugenia Conti, Camilla Gesi, Claudia Carmassi, Liliana Dell'Osso, Giovanni Cioni, Giovanni Cioni, Filippo Muratori, Filippo Muratori, Andrea Guzzetta, Andrea Guzzetta   +12 more
doaj   +1 more source

A reciprocal model of face recognition and autistic traits: evidence from an individual differences perspective. [PDF]

PLoS ONE, 2014
Although not a core symptom of the disorder, individuals with autism often exhibit selective impairments in their face processing abilities. Importantly, the reciprocal connection between autistic traits and face perception has rarely been examined ...
Drew W R Halliday, Stuart W S MacDonald, K Suzanne Scherf, James W Tanaka   +3 more
doaj   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source