Results 71 to 80 of about 24,165 (274)

Delineating the autistic phenotype in children with neurofibromatosis type 1

Molecular Autism, 2022
Background Existing research has demonstrated elevated autistic behaviours in children with neurofibromatosis type 1 (NF1), but the autistic phenotype and its relationship to other neurodevelopmental manifestations of NF1 remains unclear. To address this
Anita K. Chisholm, Kristina M. Haebich, Natalie A. Pride, Karin S. Walsh, Francesca Lami, Alex Ure, Tiba Maloof, Amanda Brignell, Melissa Rouel, Yael Granader, Alice Maier, Belinda Barton, Hayley Darke, Gabriel Dabscheck, Vicki A. Anderson, Katrina Williams, Kathryn N. North, Jonathan M. Payne   +17 more
doaj   +1 more source

Visual orienting in the early broader autism phenotype: disengagement and facilitation [PDF]

Journal of Child Psychology and Psychiatry, 2009
Background:  Recent studies of infant siblings of children diagnosed with autism have allowed for a prospective approach to examine the emergence of symptoms and revealed behavioral differences in the broader autism phenotype within the early years.
Elsabbagh, Mayada, Volein, Agnes, Holmboe, Karla, Tucker, Leslie, Csibra, Gergely, Baron-Cohen, Simon, Bolton, Patrick, Charman, Tony, Baird, Gillian, Johnson, Mark H   +9 more
openaire   +3 more sources

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

What Do We Know About the Preterm Behavioral Phenotype? A Narrative Review

Frontiers in Psychiatry, 2020
Preterm birth is associated with a significantly increased risk for childhood and adolescent psychopathology relative to full-term birth, with an inverse relationship between gestational age at birth and later risk for psychopathology.
Grace C. Fitzallen, Grace C. Fitzallen, H. Gerry Taylor, Samudragupta Bora   +3 more
doaj   +1 more source

Greater magnocellular saccadic suppression in high versus low autistic tendency suggests a causal path to local perceptual style [PDF]

Royal Society Open Science, 2015
Saccadic suppression—the reduction of visual sensitivity during rapid eye movements—has previously been proposed to reflect a specific suppression of the magnocellular visual system, with the initial neural site of that suppression at or prior to ...
David P. Crewther, Daniel Crewther, Stephanie Bevan, Melvyn A. Goodale, Sheila G. Crewther   +4 more
doaj   +1 more source

ハハオヤ　ノ　ジヘイショウ　コウイキ　ヒョウゲンガタ　ガ　ジヘイショウ　スペクトラムジ　ノ　タイジン　オウトウセイ　ヲ　ヨソク　スル [PDF]

Chiaki Hasegawa, Mitsuru Kikuchi, Yuko Yoshimura, Hirotoshi Hiraishi, Toshio Munesue, Hideo Nakatani, Haruhiro Higashida, Minoru Asada, Manabu Oi and Yoshio Minabe, Broader autism phenotype in mothers predicts social responsiveness in young children with
ハセガワ, チアキ, 長谷川, 千秋   +1 more
core   +1 more source

Remote Language Assessment in School‐Age Children With Phelan–McDermid Syndrome and Genotype–Phenotype Correlation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT People with Phelan–McDermid syndrome (PMS) have reduced speech and language abilities, yet little research has profiled the communication abilities in this population. The purpose of this study was threefold: identifying the language and communication profiles of school‐aged children with PMS, identifying genetic contributions to language and ...
Sarah Quadri‐Valverde, Jessica Klusek, Linda D. Ward, Diana Ivankovic, Nancy Powers, Vijay Shankar, Rachel A. Lyman, Trudy F. C. Mackay, William Bridges, Katy Phelan, Curtis Rogers, Luigi Boccuto, Sara M. Sarasua   +12 more
wiley   +1 more source

Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. [PDF]

PLoS ONE, 2015
Autism spectrum disorder comprises several neurodevelopmental conditions presenting symptoms in social communication and restricted, repetitive behaviors.
Daniela Brunner, Patricia Kabitzke, Dansha He, Kimberly Cox, Lucinda Thiede, Taleen Hanania, Emily Sabath, Vadim Alexandrov, Michael Saxe, Elior Peles, Alea Mills, Will Spooren, Anirvan Ghosh, Pamela Feliciano, Marta Benedetti, Alice Luo Clayton, Barbara Biemans   +16 more
doaj   +1 more source

Diary reports of concerns in mothers of infant siblings of children with autism across the first year of life [PDF]

, 2015
We examined the home-based concerns reported by mothers of infant siblings of children with autism across the first year of life. At all three ages measured, mothers of high-risk infants were significantly more likely than mothers of low-risk infants to ...
Nelson, Charles A., Tager-Flusberg, Helen, Talbott, Meagan R.   +2 more
core   +3 more sources

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source