Results 51 to 60 of about 24,165 (274)

Modeling Autistic Features in Animals [PDF]

, 2011
A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core   +1 more source

Defining language impairments in a subgroup of children with autism spectrum disorder [PDF]

, 2015
Autism spectrum disorder (ASD) is diagnosed on the basis of core impairments in pragmatic language skills, which are found across all ages and subtypes.
A Bailey, AG Kamhi, AP Association, B Saheln, BS Abrahams, C Dollaghan, C Lord, C Lord, CD Elliott, D Bishop, D Williams, DVM Bishop, E Billstedt, E Fombonne, E Plante, E Semel, FG Happe, G Bartolucci, G Conti-Ramsden, G Dawson, GJ Harris, H Tager-Flusberg, H Tager-Flusberg, H Tager-Flusberg, H Tager-Flusberg, H Tager-Flusberg, H Tager-Flusberg, Helen Tager-Flusberg, I Rapin, IN Bespalova, J Edwards, J Ganger, J Ganger, J Piven, JA Roberts, JB Tomblin, JB Tomblin, JB Tomblin, JB Tomblin, JW Montgomery, JW Montgomery, K Lindgren, L DeFossé, LM Gauger, M Alarcon, M Alarcon, M Falcaro, M Kjelgaard, M L Rice, MA Just, ML Rice, ML Rice, MR Herbert, N Botting, N Choudhury, NM Gage, P Bolton, P Filipek, P Howlin, P Howlin, RA Muller, RJ Luyster, RK Wagner, RM Joseph, RM Joseph, S Baron-Cohen, S Consortium, S Consortium, SC Vernes, SE Fisher, SE Fisher, SE Folstein, SE Folstein, SE Gathercole, SE Gathercole, SE Weismer, SE Weismer, T Knaus, TA Knaus, TA Knaus, TL Jernigan, Y Bradford   +81 more
core   +2 more sources

Executive functions in parents of children with and without autism spectrum disorder [PDF]

روانشناسی و روانپزشکی شناخت, 2019
Introduction: Autism spectrum disorder is a neurodevelopmental disorder that its etiology has not been determined definitively. The studies that have been conducted on the characteristics of relatives of people with ASD have shown that relatives of ...
Bita Shalani, Saeid Sadeghi, Samad Rashidiyan   +2 more
doaj   +1 more source

Frontal cortex functioning in the infant broader autism phenotype

Infant Behavior and Development, 2010
Atypical attention has been proposed as a marker of the broader autism phenotype. In the present study we investigated this and the related process of inhibitory control at the youngest possible age through the study of infant siblings of children with an autism spectrum disorder (Sibs-ASD).
Holmboe, K., Elsabbagh, M., Volein, A., Tucker, Leslie, Baron-Cohen, S., Bolton, P., Charman, T., Johnson, Mark H.   +7 more
openaire   +4 more sources

O Fenótipo Ampliado do Autismo em genitores de crianças com Transtorno do Espectro Autista - TEA

Psicologia: Teoria e Pesquisa
RESUMOPesquisadores têm identificado expressões mais leves de traços do Transtorno do Espectro do Autismo - TEA em pais e irmãos destes indivíduos, que são definidas como Fenótipo Ampliado do Autismo (FAA).
Renata Giuliani Endres, Simone Steyer Lampert, Jaqueline Bohrer Schuch, Tatiana Roman, Cleonice Alves Bosa   +4 more
doaj   +1 more source

Confirmatory factor analysis of the Adult Asperger Assessment: The association of symptom domains within a clinical population [PDF]

, 2011
Autism Spectrum Disorder (ASD) is a behaviourally defined disorder characterised by impairments in three domains of social interaction, communication, and repetitive, stereotyped behaviours and activities.
Kuenssberg, Renate, McKenzie, Karen
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Reduced face identity aftereffects in relatives of children with autism. [PDF]

, 2012
Autism is a pervasive developmental condition with complex aetiology. To aid the discovery of genetic mechanisms, researchers have turned towards identifying potential endophenotypes - subtle neurobiological or neurocognitive traits present in ...
Fiorentini, Chiara, Gray, Laura, Jeffery, Linda, Pellicano, Liz, Rhodes, Gillian   +4 more
core   +2 more sources

Investigating emotional impairments in adults with autism spectrum disorders and the broader autism phenotype [PDF]

Psychiatry Research, 2013
There is an increasing interest in the socio-affective atypicalities observed in adults with autism spectrum disorder (ASD). The aim of this study was to further explore emotional responsiveness in adults with ASD using well-validated self-reports of alexithymia and to determine whether anhedonic features are part of a broader autism phenotype (BAP ...
Berthoz, S., Lalanne, C., Crane, L., Hill, E. L.   +3 more
openaire   +3 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source