Results 81 to 90 of about 2,650 (185)

Association of metabolomic aging acceleration and body mass index phenotypes with mortality and obesity‐related morbidities

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Metabolomic aging acceleration may help stratify mortality and obesity‐related morbidities risk across different BMI categories. Weight management should address Individuals with overweight or obesity, regardless of metabolomic aging, while delaying metabolomic aging is crucial for all metabolomically older groups, including those with normal weight ...
Xiaomin Zeng   +9 more
wiley   +1 more source

The initial results of using brolucizumab (Beovu®), an angiogenesis inhibitor, for choroidal neovascularization in patients with age-related macular degeneration [PDF]

open access: yesКлиническая офтальмология, 2022
N.S. Zhayvoronok1, O.V. Kolenko1–3, L.P. Danilova1,2, E.L. Sorokin1,3 1Khabarovsk Branch of the S. Fedorov Eye Microsurgery Federal State Institution, Khabarovsk, Russian Federation 2Institute of Advanced Training of Healthcare Specialists ...
N.S. Zhayvoronok   +3 more
doaj  

Intravitreal Bevacizumab in Neovascular Age-Related Macular Degeneration as First Choice: a New Italian Ruling [PDF]

open access: yes, 2020
Background: Intravitreal vascular endothelial growth factor (VEGF) inhibitors represent the mainstay of neovascular age-related macular degeneration (nAMD) treatment.
Casalino, Giuseppe   +2 more
core   +2 more sources

Peptide‐Bound Aflibercept Eye Drops for Treatment of Neovascular Age‐Related Macular Degeneration in Nonhuman Primates

open access: yesAdvanced Science, Volume 12, Issue 11, March 20, 2025.
This article demonstrates that the peptide bxyPenetratin (bxyWP) non‐covalently binds to the anti‐vascular endothelial growth factor (VEGF) protein aflibercept via hydrophobic interactions, enabling noninvasive delivery of aflibercept to the choroid and retina through conjunctival‐scleral pathway and effective inhibition of choroidal neovascularization
Xingyan Fan   +7 more
wiley   +1 more source

Brolucizumab: Evaluation of Compassionate Use of a Complex Anti-VEGF Therapy

open access: yesClinical Ophthalmology, 2021
Julianna E Murray, Aaron S Gold, Azeema Latiff, Timothy G Murray Private Practice, Miami Ocular Oncology & Retina, Miami, FL, USACorrespondence: Timothy G MurrayMiami Ocular Oncology & Retina, 6705 Red Road Suite 412, Miami, FL, 33143, USAEmail tmurray ...
Murray JE, Gold AS, Latiff A, Murray TG
doaj  

Faricimab versus bevacizumab for neovascular age‐related macular degeneration: Cost analysis based on real‐world data from the Swedish Macula Registry

open access: yesActa Ophthalmologica, Volume 103, Issue 1, Page 99-108, February 2025.
Abstract Purpose To analyse the impact on cost if faricimab is used as the first‐line treatment for neovascular age‐related macular degeneration (nAMD) compared to standard treatment with bevacizumab. Methods Retrospective registry study including real‐world data from the Swedish Macula Registry between 2017 and 2022.
Souad Abdalla   +3 more
wiley   +1 more source

Anti-vascular endothelial growth factor therapies in ophthalmology [PDF]

open access: yes
Background: Retinal diseases, including neovascular age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion, are leading causes of vision loss worldwide.
Karti, Omer   +2 more
core   +2 more sources

Occlusive retinal vasculitis associated with intravitreal Faricimab injections [PDF]

open access: yes
Purpose: We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections. Methods: A retrospective case report.
De Silva, Samantha R.   +5 more
core   +2 more sources

High-Dose Brolucizumab for Refractory Neovascular Age-Related Macular Degeneration Resistant to Standard-Dose Brolucizumab

open access: yesOphthalmology and Therapy
Introduction The aim of this study was to evaluate the efficacy and safety of escalating the dosage of intravitreal brolucizumab in patients with refractory neovascular age-related macular degeneration (AMD).
Jinsoo Kim   +3 more
doaj   +1 more source

Short-Term Treatment Outcomes of Brolucizumab in Patients with Neovascular Age-Related Macular Degeneration: A Multicentre Indian Real-World Evidence Study

open access: yesClinical Ophthalmology, 2023
Debdulal Chakraborty,1 Milan Thakkar,2 Ramesh Venkatesh,3 Sangeeta Roy,4 Maulik Bhavsar,5 Helene Karcher6 1Disha Eye Hospital, Kolkata, West Bengal, India; 2Dr.
Chakraborty D   +5 more
doaj  

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