Results 81 to 90 of about 6,161 (228)

Toxicological analyses of the bone matrix: Successes and challenges

Archaeometry, Volume 67, Issue 4, Page 1001-1021, August 2025.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano, Lucie Biehler‐Gomez, Cristina Cattaneo, Domenico Di Candia   +3 more
wiley   +1 more source

Effects of anxiolytic drugs on rewarding and aversive behaviors induced by intracranial stimulation. [PDF]

, 2003
In considering the characteristics of the action of anxiolytic drugs and their mechanism in the brain, it may be necessary not only to study the behavioral pharmacology but also to perform brain site research.
Araki, Hiroaki, Futagami, Koujiro, Gomita, Yutaka, Ichimaru, Yasuyuki, Moriyama, Minehiro   +4 more
core   +1 more source

Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry

Drug Testing and Analysis, Volume 17, Issue 7, Page 954-988, July 2025.
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain in the laboratory, for example, in terms of calibrator solution preparation. A fast, simple, and robust liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of 82 classic ...
Andrea E. Steuer, Maja Keller, Thomas Kraemer, Sandra N. Poetzsch   +3 more
wiley   +1 more source

Avaliação das intoxicações medicamentosas em Portugal [PDF]

, 2008
Os medicamentos são responsáveis pela maior parte das intoxicações agudas nos países ocidentais e Portugal não é excepção. Este artigo analisa o perfil dos medicamentos envolvidos em intoxicações no nosso país, com base em casos e óbitos decorrentes de
Borges, Arlinda, Carvalho, Márcia, Dias, Mário João, Ferreira, Andreia Manuela Ramos, Monsanto, Paula, Rangel, Rui   +5 more
core  

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

Drug Testing and Analysis, Volume 17, Issue 6, Page 903-914, June 2025.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces, Ana de‐Castro‐Rios, Angela Lopez‐Rabuñal, Maria Cobo‐Golpe, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Medicamentos ansiolíticos utilizados por la población que asiste a farmacias privadas de la Ciudad de Managua, Marzo-Septiembre 2009 [PDF]

, 2010
Los Ansiolíticos son los fármacos más utilizados por la población y es muy importante el estudio de estos medicamentos debido a su uso irracional.
Castillo Largaespada, Sofía Vanessa, González Acosta, Brenda Carolina   +1 more
core  

Megadose bromazepam dependence.

Psychiatria Danubina, 2016
Benzodiazepines (BZDs) are among the most widely prescribed drugs in developed countries. Since BZDs can produce tolerance and dependence even in a short time, their use is recommended for a very limited time. However, these recommendations have been largely disregarded. The chronic use of BZDs causes a number of serious side effects, i.e.
Bastide, Anaïs, de Codt, Aloïse, Monhonval, Pauline, Bongaerts, Xavier, Tecco, Juan Martin   +4 more
openaire   +3 more sources

Concurrent Prescribing of Opioids and Sedative‐Hypnotic Drugs for Long‐Term Use in Australian General Practice: A Cross‐Sectional Analysis Using MedicineInsight

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT The number of unintentional deaths involving opioid and/or benzodiazepine use continues to increase in Australia. This study examined patterns of concurrent prescribing of opioids and benzodiazepines/Z‐drugs (BZDs) for long‐term use in Australian general practice.
Susan Williams, Josie Rositano, Claudia Haeusler, Meghana Bhat, Kimberley Omond, Nigel Stocks, David Gonzalez‐Chica   +6 more
wiley   +1 more source

SOZIALPHOBIE: EPIDEMIOLOGIE, BIOLOGIE UND THERAPIE [PDF]

, 2009
Social anxiety disorder (SAD) is considered to be one of the most common anxiety disorders. Despite its high prevalence, the disorder is still considerably underdiagnosed and undertreated.
Andreas Hahn, Christoph Spindelegger, Elena Akimova, Martin Fink, Rupert Lanzenberger, Siegfried Kasper   +5 more
core   +1 more source

Automated and Fully Validated High‐Throughput LC‐MS/MS Assay for Analyzing Multiple Drugs of Abuse in Oral Fluids Using Novel Features in Sample Preparation and Chromatographic Conditions

Journal of Mass Spectrometry, Volume 60, Issue 5, May 2025.
ABSTRACT Oral fluid sampling offers advantages over other biological matrices, mainly due to its noninvasive procedure avoiding privacy intrusion. The fully automated sample preparation procedure is based on salting‐out assisted liquid–liquid extraction (SALLE) combined with high‐efficiency LC‐MS/MS methods for both screening and confirmation of 37 ...
Joakim Tan, Alexia Rylski, Anders Bergqvist, Niclas Nikolai Stephanson   +3 more
wiley   +1 more source