Results 91 to 100 of about 228,641 (336)

Immunological features of chronic obstructive pulmonary disease (COPD) induced by indoor pollution and cigarette smoke [PDF]

, 2012
Epigenetics is defined as heritable changes that affect gene expression without altering the DNA sequence. Epigenetic regulation of gene expression is facilitated through different mechanisms such as DNA methylation, histone modifications and RNA ...
Adcock, IM, Barnes, PJ, Heidarnazhad, H, Masjedi, MR, Mortaz, E   +4 more
core   +4 more sources

Awareness regarding childhood asthma in Saudi Arabia

Annals of Thoracic Medicine, 2016
Objective: Assessing the knowledge and awareness of the Saudi society about bronchial asthma in children. Methods: Structured questionnaires were randomly distributed to 1039 Saudi Arabians in May 2014 at Jeddah, Riyadh, and Dammam.
Saleh Al-Harbi, Adel S Al-Harbi, Abdullah Al-Khorayyef, Mansour Al-Qwaiee, Abdullah Al-Shamarani, Wafa Al-Aslani, Hayat Kamfar, Osama Felemban, Mohammed Barzanji, Naser Al-Harbi, Ruqaia Dhabab, Mohammed Ahmed Al-Omari, Abdullah Yousef   +12 more
doaj   +1 more source

Bronchial Diseases are Insufficiently Defined with the Term COPD. [PDF]

Int J Chron Obstruct Pulmon Dis, 2021
von Wichert P.
europepmc   +1 more source

Unique Aerofoil‐Structured Microfluidics for High Throughput Lipid Nanoparticle Formulation Screening and Scale‐up

Advanced Science, EarlyView.
This study presents aerofoiled microfluidic structures optimized for efficient mixing and lipid nanoparticle (LNP) formation across broad flow rates. Based on this design, two dedicated systems are introduced: MiNANO‐form for high‐throughput formulation screening and MiNANO‐scale for continuous large‐scale production, enabling reproducible, high ...
Dongsheng Liu, Mingzhi Yu, Yuguo Zhang, Allen Mathew, Tianyu Guan, Liang Yao, Xianqing Wang, Wenxin Wang, Nan Zhang   +8 more
wiley   +1 more source

Analysis of the prevalence and experience of treatment of allergic diseases of the respiratory tract in Mongolia

Медицинская иммунология
Allergic diseases of the respiratory tract (allergic rhinitis and bronchial asthma) are the leading pathology in therapeutic practice. The results of a meta-analysis in the East Asian region showed that the overall prevalence of bronchial asthma and ...
P. V. Berezhansky, B. Tuvshinbayar, B. Sangidorzh, T. R. Uskova, N. S. Tataurshchikova   +4 more
doaj   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenke, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Pathogenetic Reasoning of Administration of Mucolytic Agents for Respiratory Diseases in Children

Zdorovʹe Rebenka, 2015
The paper presents the mechanisms of cough and bronchial obstruction in lesions of the respiratory tract of various origins. The effect of microbial biofilms on the course of diseases was considered particularly. The methods to restore bronchial drainage
Ye.I. Yulish
doaj   +1 more source

長期間喫煙による気管支唱息,肺気腫の病態的変化 [PDF]

, 2004
The influence of long-term cigarette smoking on the pathophysiology of chronic respiratory diseases with obstructive ventilatory dysfunction was discussed in patients with asthma and pulmonary emphysema (PE). 1.
Ashida, Kozo, Fujii, Makoto, Hamada, Masanori, Hosaki, Yasuhiro, Iwagaki, Naofumi, Mitsunobu, Fumihiro, Takata, Shingo, Tanizaki, Yoshiro   +7 more
core   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Research progress on free fatty acid receptors and bronchial asthma

Alergologia Polska
Bronchial asthma is a chronic respiratory disease characterized by reversible airflow limitation, including airway hyperresponsiveness, airway inflammation and airway remodeling.
Fangxin Cao, Na Lin, Juntao Lin, Gai Yang, Xintong Wang   +4 more
doaj   +1 more source