Results 211 to 220 of about 144,143 (306)

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

open access: yesAllergy, EarlyView.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata   +6 more
wiley   +1 more source

CT findings in biomass smoke-associated interstitial lung disease: A retrospective analysis. [PDF]

open access: yesJ Clin Imaging Sci
Bendetson JG   +5 more
europepmc   +1 more source

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

open access: yesAllergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin   +4 more
wiley   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

open access: yesAllergy, EarlyView.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler   +22 more
wiley   +1 more source

Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood

open access: yesAllergy, EarlyView.
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily   +7 more
wiley   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

open access: yesAllergy, EarlyView.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow   +22 more
wiley   +1 more source

Targeting CD30L Alleviates Airway Remodeling via JNK/p38 MAPK Pathway in OVA-Induced Asthmatic Mice. [PDF]

open access: yesAllergy Asthma Immunol Res
Xu C   +15 more
europepmc   +1 more source

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