Results 231 to 240 of about 224,661 (311)

Emerging Risk: Intranasal Tin Exacerbates Allergic Rhinitis in Humans and Mice

open access: yes
Allergy, EarlyView.
Delgama A. S. M. Nishadhi   +9 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

open access: yesAllergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake   +8 more
wiley   +1 more source

Long-Term Prognosis of Adult Patients with Persistent Cough Post COVID-19 and Its Risk Factors: A Nationwide Prospective Study. [PDF]

open access: yesLung
He W   +37 more
europepmc   +1 more source

What Difference Does Language Make? Comparing Systematic Evidence Reviews of Vietnamese and English Language Literatures on Climate Change and the Health of Outdoor Workers

open access: yesArea, EarlyView.
Short Abstract This paper compares two systematic literature reviews—one in English and one in Vietnamese—to examine how language shapes the production and framing of knowledge on climate change and health. It highlights significant differences in methods, assumptions and policy framings, and argues that linguistic boundaries are not just technical ...
Anh Ngoc Vu   +4 more
wiley   +1 more source

Video-assisted thoracoscopic surgical management of benign esophago-pulmonary fistula. [PDF]

open access: yesLung India
Pulle MV   +9 more
europepmc   +1 more source

Checkpoint inhibitors, obinutuzumab plus PET‐adapted ultra‐low dose nodal radiotherapy yield high efficacy in treatment‐naïve follicular lymphoma: Results from the phase II ‘FLUORO’ study

open access: yesBritish Journal of Haematology, EarlyView.
Summary Follicular lymphoma (FL) first‐line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment‐naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combination checkpoint inhibition (atezolizumab) and obinutuzumab (6 cycles) with positron emission tomography (PET)
Arina Martynchyk   +15 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

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