Results 71 to 80 of about 16,360 (203)
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Serum levels of vitamin D, magnesium, and calcium in patients with stable bronchial asthma
Background Vitamin D has multiple effects on the innate and adaptive immune system. Vitamin D has immunomodulation effects that are able to decrease the inflammatory reaction included in the bronchial asthma; thus, it plays an important effect in the ...
Mona T Hussein +2 more
doaj +1 more source
ABSTRACT Background The treatment and prevention of bronchial asthma continue to present significant challenges. Mendelian randomization (MR) has been extensively employed to identify novel therapeutic targets. Consequently, we conducted a systematic MR analysis across the druggable genome to identify potential therapeutic targets for asthma.
Haijiao Wang +4 more
wiley +1 more source
Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks +18 more
wiley +1 more source
Eosinophil granule proteins and bronchial asthma
For over 100 years, the association of eosinophils with bronchial asthma has been known. Over the past 20 years, the proteins comprising the eosinophil granule have been isolated and characterized.
Gerald J Gleich
doaj +1 more source
The impact of cold on the respiratory tract and its consequences to respiratory health [PDF]
The increasing use, and sometimes the abuse, particularly in industrialized countries of air conditioning at home, in car, hotel and shopping centres has highlighted new emerging public health issues, resulting from exposure of the airways to cool air or,
Annesi-Maesano, Isabella +5 more
core +1 more source
ABSTRACT Quadriplegia often leads to severe respiratory impairment, accompanied by distressing symptoms such as dyspnoea and breathlessness. Ventilator weaning remains a challenge in the acute phase of high cervical spinal cord injury. We present the case of a 27‐year‐old man with traumatic C5–C6 quadriplegia.
Christine Bernard +5 more
wiley +1 more source
EAACI position paper on occupational rhinitis [PDF]
The present document is the result of a consensus reached by a panel of experts from European and non-European countries on Occupational Rhinitis (OR), a disease of emerging relevance which has received little attention in comparison to occupational ...
J Bousquet +215 more
core +2 more sources
Negative pressure pulmonary edema (NPPE) is a rare but potentially life‐threatening complication resulting from the generation of markedly negative intrathoracic pressure in response to upper airway obstruction (UAO). This leads to disruption of the alveolar–capillary barrier and transudation of fluid into the alveolar spaces.
Bartłomiej Kołodziejczyk +3 more
wiley +1 more source
The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse
Background Interleukin 15 (IL-15) is a growth and modulating factor for B, T lymphocytes and natural killer cells (NK). Its action on innate and adaptive immunity is modulated by its alpha chain receptor (IL-15Rα).
Antoine Moui +6 more
doaj +1 more source

