Results 131 to 140 of about 66,208 (273)

Mixed Invasive Aspergillus–Mucorales Pulmonary Coinfection in a Diabetic Patient: An Uncommon Dual Fungal Pneumonia and Literature Review

open access: yesRespirology Case Reports, Volume 14, Issue 10, October 2026.
Our case describes a rare lung co‐infection caused by Aspergillus and Mucorales in a 61‐year‐old man with uncontrolled diabetes and chronic kidney disease. The diagnosis was made by BAL PCR and biopsy. Despite antifungal treatment, the patient worsened and died.
Vinay Venugopal   +7 more
wiley   +1 more source

A Prospective Observational Study Evaluating the PRogression Of BronchiEctasis in COPD Patients - Results from the PROBE - COPD Study

open access: yesInternational Journal of COPD
Rajesh Venkitakrishnan,1 Athulya Sudheendranath,2 Anand Vijay,1 Divya Ramachandran,1 Melcy Cleetus,1 Hasha Thankam Somson,1 Susan John3 1Department of Pulmonary Medicine, Rajagiri Hospital, Aluva, Kochi, Kerala, India; 2Department of Pulmonary Medicine ...
Venkitakrishnan R   +6 more
doaj  

Associations of Serum CIRP and CXCL5 With Prognosis and Neutrophil Extracellular Traps in Pediatric Mycoplasma pneumoniae Pneumonia

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 10, October 2026.
This study investigated serum levels of cold‐inducible RNA‐binding protein (CIRP) and C‐X‐C motif chemokine ligand 5 (CXCL5) in 485 children with Mycoplasma pneumoniae pneumonia. Elevated levels of both biomarkers were independently associated with poor prognosis and positively correlated with neutrophil extracellular trap markers, suggesting their ...
Litao Wan   +7 more
wiley   +1 more source

The clinical impacts of lung microbiome in bronchiectasis with fixed airflow obstruction: a prospective cohort study

open access: yesRespiratory Research
Background Airflow obstruction is a hallmark of disease severity and prognosis in bronchiectasis. The relationship between lung microbiota, airway inflammation, and outcomes in bronchiectasis with fixed airflow obstruction (FAO) remains unclear.
Yen-Fu Chen   +13 more
doaj   +1 more source

Biomarkers in bronchiectasis

open access: yesEuropean Respiratory Review
Bronchiectasis is a heterogeneous disease with multiple aetiologies and diverse clinical features. There is a general consensus that optimal treatment requires precision medicine approaches focused on specific treatable disease characteristics, known as treatable traits.
Johnson, Emma   +2 more
openaire   +4 more sources

Selective MicroRNA Dysregulation in IPF‐Derived Mesenchymal Stromal Cells Suggests Restricted Regulatory Remodeling

open access: yesThe FASEB Journal, Volume 40, Issue 18, 30 September 2026.
The schematic workflow illustrates next‐generation sequencing of lung‐derived mesenchymal stromal cells (MSCs) from IPF patients and controls. Rather than broad epigenetic reprogramming, IPF‐MSCs exhibit a remarkably restricted down‐regulation of only three critical microRNAs: hsa‐miR‐373‐3p, hsa‐miR‐486‐5p, and hsa‐miR‐449a.
Mariangela Di Vincenzo   +5 more
wiley   +1 more source

Microbiological characteristics of the lower airway in adults with bronchiectasis: a prospective cohort study

open access: yesRespiratory Research
Background Microbial infection and colonization are frequently associated with disease progression and poor clinical outcomes in bronchiectasis. Identification of pathogen spectrum is crucial for precision treatment at exacerbation of bronchiectasis ...
Jie-lin Duan   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Reversible bronchiectasis [PDF]

open access: yesThorax, 2021
Chuan Tai Foo, Sumit Karia, Jurgen Herre
openaire   +2 more sources

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah   +8 more
wiley   +1 more source

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