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Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms of bronchiectasis include persistent bacterial infections, dysregulated immune responses, impaired mucociliary clearance and airway obstruction.
Chalmers, James D +4 more
+10 more sources
Bronchiectasis is a final common pathway of a wide variety of underlying conditions including infectious, autoimmune, allergic, genetic and inflammatory conditions. Patients experience a chronic disease with variable clinical symptoms and course, but most experience cough, sputum production and recurrent exacerbations.
Miguel Barbosa, James D. Chalmers
openaire +3 more sources
Utility of routine screening for alpha-1 antitrypsin deficiency in patients with bronchiectasis [PDF]
Alpha-1 antitrypsin deficiency (AATD) is a cause of bronchiectasis. Guidelines for bronchiectasis from the British Thoracic Society do not recommend to routinely test patients for AATD. In contrast, guidelines for AATD recommend routine screening.
Carreto, Luis +9 more
core +3 more sources
Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST) [PDF]
BACKGROUND: Recurrent bronchiectasis exacerbations are related to deterioration of lung function, progression of the disease, impairment of quality of life, and to an increased mortality.
A Spinou +26 more
core +3 more sources
High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain +37 more
core +1 more source
Unraveling the Complexities of Kartagener's Syndrome: A Case of Bronchiectasis, Isolated Dextrocardia, and Primary Ciliary Dyskinesia in an Adult With Chronic Respiratory Symptoms. [PDF]
ABSTRACT Kartagener's Syndrome (KS), a rare autosomal recessive disorder and a subset of Primary Ciliary Dyskinesia (PCD), is characterized by chronic sinusitis, bronchiectasis, and, in approximately 50% of cases, situs inversus. This condition arises from genetic mutations that impair motile cilia function, leading to defective mucociliary clearance ...
Khalil I, Abrar S, Ahmed ST, Hossain MI.
europepmc +2 more sources
Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier [PDF]
An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bronchi,
Fitzgerald, E +2 more
core +2 more sources
The frequency of diagnosing bronchiectasis is increasing around the world. Cystic fibrosis is the most common inherited cause of bronchiectasis, but there is increasing recognition of significant numbers of patients with bronchiectasis from various causes.
Kim, Changhwan, Kim, Dong-Gyu
openaire +2 more sources
Clinical features of patients with asthma, bronchiectasis, and combination of both conditions
Background: Asthma and bronchiectasis are critical diseases for public health. In some patients, asthma and bronchiectasis exist together, and bronchiectasis negatively affects asthma control.
Fatih Uzer, Zehra Boztepe, Aykut Cilli
doaj +1 more source
Background Tuberculosis (TB) is considered one of the most common causes of bronchiectasis. Bronchiectasis increases clinical and financial burden of patients with TB.
Maiada K. Hashem +3 more
doaj +1 more source

