Results 31 to 40 of about 51,706 (265)

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

Angewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans, Nishu Yadav, Wouter A. Remmerswaal, Daan Hoogers, Koen N. A. van de Vrande, Sarah Hosking, Ana Poveda, Jeroen D. C. Codée, Jesús Jiménez‐Barbero, Martina Delbianco, Gavin J. Miller   +10 more
wiley   +2 more sources

Research progress on pulmonary aspergillosis in patients with bronchiectasis [PDF]

Xin yixue, 2022
Bronchiectasis is a chronic inflammatory disease of the airway in which one or more proximal bronchi （diameter greater than 2 mm） are irreversibly dilated caused by a variety of causes.
Wang Shixiong, Zhang Haochuan, Li You, Deng Zhenkai, Huang He
doaj   +1 more source

Increased mortality in patients with non cystic fibrosis bronchiectasis with respiratory comorbidities

Scientific Reports, 2021
There are limited data regarding whether mortality is higher in patients with non cystic fibrosis bronchiectasis (bronchiectasis) than in those without bronchiectasis.
Hayoung Choi, Bumhee Yang, Yun Jin Kim, Sooim Sin, Yong Suk Jo, Youlim Kim, Hye Yun Park, Seung Won Ra, Yeon-Mok Oh, Sung Jun Chung, Yoomi Yeo, Dong Won Park, Tai Sun Park, Ji-Yong Moon, Sang-Heon Kim, Tae-Hyung Kim, Ho Joo Yoon, Jang Won Sohn, Hyun Lee   +18 more
doaj   +1 more source

How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old

Respiratory Medicine Case Reports, 2017
Background and aims: To specify the prevalence of patients diagnosed with CF at age of ≥60 year-old and to analyze their characteristics. Patients and methods: Observational study of CF patients which were diagnosed at age ≥60 year-old.
C. Prados, M. Lerín, J.J. Cabanillas, L. Gómez-Carrera, R. Álvarez-Sala, M.T. Martinez, L. Máiz, R.M. Girón, A. Solé, M. Martínez, S. Quirós   +10 more
doaj   +1 more source

Endotypes in bronchiectasis: moving towards precision medicine. A narrative review.

Pulmonology, 2023
Bronchiectasis is a highly complex entity that can be very challenging to investigate and manage. Patients are diverse in their aetiology, symptoms, risk of complications and outcomes. "Endotypes"- subtypes of disease with distinct biological mechanisms,
M. Martins, H. Keir, J. Chalmers
semanticscholar   +1 more source

Outcome and prognostic factors after lung transplantation for bronchiectasis other than cystic fibrosis

BMC Pulmonary Medicine, 2021
Background While lung transplant (LTX) can be an effective therapy to provide the survival benefit in selected populations, post-transplant outcome in LTX recipients with bronchiectasis other than cystic fibrosis (CF) has been less studied.
Takashi Hirama, Fumiko Tomiyama, Hirotsugu Notsuda, Tatsuaki Watanabe, Yui Watanabe, Hisashi Oishi, Yoshinori Okada   +6 more
doaj   +1 more source

The prevalence of bronchiectasis in patients with alpha-1 antitrypsin deficiency: initial report of EARCO

Orphanet Journal of Rare Diseases, 2023
Background Although bronchiectasis has been recognised as a feature of some patients with Alpha1-Antitrypsin deficiency the prevalence and characteristics are not widely known.
R. Stockley, A. Pye, J. De Soyza, A. Turner, M. Miravitlles, María Hanan Carlota José Luis Jan Catarina Juan Luis Ang Torres-Duran Tanash Rodríguez-García López-Campos , M. Torres-Durán, H. Tanash, Carlota Rodríguez-García, J. López-Campos, J. Chlumsky, Catarina Guimarães, J. Rodríguez-Hermosa, A. Corsico, C. Martínez‐González, J. M. Hernández-Pérez, A. Bustamante, D. Parr, F. Casas-Maldonado, A. Hećimović, W. Janssens, B. Lara, M. Barrecheguren, Cruz González, J. Stolk, Christian F. Clarenbach   +25 more
semanticscholar   +1 more source

Bronchiectasis and increased mortality in patients with corticosteroid-dependent severe asthma: a nationwide population study

Therapeutic Advances in Respiratory Disease, 2020
Background: Long-term corticosteroid (CS) use is associated with increased mortality in patients with asthma, and comorbid bronchiectasis is also associated with frequent asthma exacerbation and increased healthcare use.
Hayoung Choi, Hyun Lee, Jiin Ryu, Sung Jun Chung, Dong Won Park, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim   +7 more
doaj   +1 more source

Bronchiectasis-associated hospitalizations in Germany, 2005-2011: a population-based study of disease burden and trends. [PDF]

PLoS ONE, 2013
BACKGROUND: Representative population-based data on the epidemiology of bronchiectasis in Europe are limited. The aim of the present study was to investigate the current burden and the trends of bronchiectasis-associated hospitalizations and associated ...
Felix C Ringshausen, Andrés de Roux, Mathias W Pletz, Nina Hämäläinen, Tobias Welte, Jessica Rademacher   +5 more
doaj   +1 more source

Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021: a systematic review and meta-analysis

BMJ Open, 2022
Objective To accurately estimate the global prevalence of non-tuberculous mycobacteria (NTM) in adults with non-cystic fibrosis (non-CF) bronchiectasis and to determine the proportion of NTM species and subspecies in clinical patients from 2006 to 2021 ...
Yunchun Zhou, Wei-qiang Mu, Jihua Zhang, S. Wen, S. Pakhalé   +4 more
semanticscholar   +1 more source