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Bronchiectasis [PDF]

Терапевтический архив, 2017
The paper presents information on possible approaches to the classification, pathogenesis, and determination of the etiological causes of bronchiectasis. It discusses a group of bronchiectasis-associated diseases. It gives a detailed diagnostic algorithm
A G Chuchalin
doaj   +4 more sources

Bronchiectasis [PDF]

Nature Reviews Disease Primers, 2018
Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms of bronchiectasis include persistent bacterial infections, dysregulated immune responses, impaired mucociliary clearance and airway obstruction.
Chalmers, James D, Chang, Anne B, Chotirmall, Sanjay H, Dhar, Raja, McShane, Pamela J   +4 more
core   +12 more sources

Bronchiectasis [PDF]

La Presse Médicale, 2023
Bronchiectasis is a final common pathway of a wide variety of underlying conditions including infectious, autoimmune, allergic, genetic and inflammatory conditions. Patients experience a chronic disease with variable clinical symptoms and course, but most experience cough, sputum production and recurrent exacerbations.
Miguel Barbosa, James D. Chalmers
openaire   +4 more sources

Real-World Management of Difficult Exacerbations of Bronchiectasis: A Case Study to Illustrate How Guidelines Can Support Best Practice. [PDF]

Clin Case Rep
ABSTRACT Timely management of exacerbations and optimisation of ongoing care are vital in preventing disease progression and preserving outcomes and quality of life in patients with bronchiectasis. This retrospective case review underscores the importance of the new ERS guidelines in supporting multidisciplinary teams to provide optimal care for their ...
Bianca H, Toby C, Anand S, Paul M.
europepmc   +2 more sources

Web-Based Physiotherapy Resources for Bronchiectasis: Evaluation of Content, Quality, and Implementation Evidence. [PDF]

Physiother Res Int
ABSTRACT Background and Purpose For people with bronchiectasis, health information, including guidance on physiotherapy management, is readily accessible online. However, the content and quality of web‐based resources, and the enablers and barriers to implementing this information into clinical care, remain unclear.
Turner CA, Chang AB, Hall K, Lee AL.
europepmc   +2 more sources

Could Hepcidin Be a Phenotype-Related Biomarker in Patients with Stable Bronchiectasis? [PDF]

Life
Hepcidin centrally regulates iron homeostasis and responds to inflammation, iron status, hypoxia, and erythropoietic signaling, yet circulating hepcidin in stable bronchiectasis is poorly characterized. We compared serum hepcidin between 61 patients with
Gulcin Yilmaz Gunes, Hikmet Çoban, Fuat Erel, Merve Akış Yılmaz, Nurhan Sarioglu, Mustafa Colak, Merve Yumrukuz Senel, Ayşe Dilvin Mansır Elmalı   +7 more
doaj   +2 more sources

Population Pharmacokinetic Analysis of Brensocatib in Adult and Adolescent Patients With Non‐Cystic Fibrosis Bronchiectasis [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Brensocatib, a competitive and reversible oral DPP1 inhibitor, at 10 and 25 mg significantly reduced pulmonary exacerbation burden, and 25 mg also reduced lung function decline vs. placebo in patients with non‐cystic fibrosis bronchiectasis, hereafter bronchiectasis, in ASPEN (NCT04594369).
Usansky H, Cammarata A, Li C, Au Yeung S, Rubino C, Wang L, Teper A, Fernandez C, Mange K.   +8 more
europepmc   +2 more sources

Patient attitudes to nebulised antibiotics in the treatment of bronchiectasis: a mixed-methods study

ERJ Open Research, 2023
Background Regular daily nebulised antibiotics are widely used in managing bronchiectasis. This patient population typically has severe bronchiectasis requiring multiple other medications.
John Davison, Anna Robinson-Barella, Gareth Davies, Marina Campos-Hinojosa, Camille Collins, Andy Husband, Daniel Okeowo, Katy L.M. Hester, Richard Lee, Tim Rapley, Anthony De Soyza   +10 more
doaj   +1 more source

‘Teach me how to look after myself’: What people with bronchiectasis want from education in a pulmonary rehabilitation setting

The Clinical Respiratory Journal, 2023
Introduction Pulmonary rehabilitation is recommended for people with bronchiectasis. Various education topics are included in these programmes, but the content is largely guided by the needs of people with other respiratory conditions.
Annemarie L. Lee, Rebecca Smith, Lucy Burr, Anne B. Chang, Chien‐Li Holmes‐Liew, Paul King, Peter Middleton, Lucy Morgan, Daniel Smith, Rachel Thomson, Grant Waterer, Conroy Wong, Rachael McAleer   +12 more
doaj   +1 more source

Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea

ERJ Open Research, 2021
Despite the burden of bronchiectasis, there is little data from South Korea regarding asymptomatic bronchiectasis. We aimed to investigate the prevalence of bronchiectasis based on computed tomography (CT) findings, with emphasis on asymptomatic ...
Soo Han Kim, Young Ju Jung, Myung-Su Ko, Sei Won Lee, Jae Seung Lee, Yeon-Mok Oh   +5 more
doaj   +1 more source