Results 51 to 60 of about 80,333 (208)
EpigeneticsThis study aims to discover drug targeted genes and explore the potential epigenetics mechanisms in bronchiectasis. Cis-expression quantitative trait locus (eQTL) was obtained as exposure, and bronchiectasis from the FinnGen cohort was used as outcome ...
Jiangyue Qin +7 more
doaj +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Medical Causes of Hospitalisation among Patients with Bronchiectasis: A Nationwide Study in Japan
PathogensPurpose: Although the international guidelines for managing bronchiectasis are centred on preventing the exacerbation of bronchiectasis, the medical causes of admissions to hospital among patients with bronchiectasis have not been fully investigated ...
Akihiko Hagiwara +7 more
doaj +1 more source
Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis. [PDF]
, 2012 Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).
Dawes, PT, Mattey, DL, Nixon, NB
core +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Idiopathic pulmonary fibrosis: evaluation of progression and prognosis after the ATS/ERS/JRS/ALAT statement 2011 [PDF]
, 2012 Objectives The prediction of usual interstitial pneumonia (UIP) progression and prognosis by the a application of HRCT criteria pattern recommended by ATS/ERS/JALAT guidelines 2011 Materials and methods Two radiologists after assessing the baseline HRCT ...
ROMEI, CHIARA
core
Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk [PDF]
, 2020 Background and Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. COPD is expensive to treat, whereas the quality of care is difficult to evaluate due to the high prevalence of multi ...
Chukmaitov, Askar +3 more
core +1 more source
Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: A narrative review [PDF]
, 2019 Chronic lung disease and admissions due to acute respiratory failure (ARF) are becoming increasingly common. Consequently, there is a growing focus on optimizing respiratory support, particularly non-invasive respiratory support, to manage these ...
Cortegiani A. +2 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng +4 more
wiley +1 more source
SAGE Open MedicineIntroduction: Bronchiectasis is a chronic respiratory disease caused by various respiratory and systemic conditions. It is now considered a potentially reversible disease, particularly when diagnosed early and managed with appropriate respiratory care ...
Phanthila Sitthikarnkha +5 more
doaj +1 more source