Results 71 to 80 of about 66,208 (273)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Pulmonary function and airflow limitation in bronchiectasis: a case-control study of two independent cohorts

BMJ Open Respiratory Research
Background Bronchiectasis is a respiratory disease structurally characterised by irreversible airway dilatation. Functional impairments are also implicated in bronchiectasis, but the detailed changes in pulmonary function and the impact of clinical ...
Bumhee Yang, Byoung Soo Kwon, Sang Haak Lee, Jae Seung Lee, Sei Won Lee, Yeon-Mok Oh, Soo Han Kim, Da Som Jeon, Young Ju Jung, Hyun-Kyung Lee   +9 more
doaj   +1 more source

Characteristics of Patients with Idiopathic Bronchiectasis in Comparison to Post-infectious Bronchiectasis in South Korea [PDF]

Tuberculosis and Respiratory Diseases
Background Bronchiectasis has a complex and heterogeneous pathogenesis, with various etiologies, the majority being idiopathic. This study aimed to examine the characteristics of patients with idiopathic bronchiectasis in comparison to those with post ...
Seo-Young Hwang, Hyun Lee, Hayoung Choi, Seung Won Ra, Yeon-Mok Oh,   +5 more
doaj   +1 more source

Gastro-oesophageal reflux disease increases healthcare use and medical costs in patients with bronchiectasis: a Korean nationwide population-based study

Therapeutic Advances in Gastroenterology, 2021
Background: Gastro-oesophageal reflux disease (GORD) is not only a common aetiology but also accompanying comorbidity of non-cystic fibrosis bronchiectasis (bronchiectasis).
Jai Hoon Yoon, Sang Hyuk Kim, Jiin Ryu, Sung Jun Chung, Youlim Kim, Chang Ki Yoon, Seung Won Ra, Yeon Mok Oh, Hayoung Choi, Hyun Lee   +9 more
doaj   +1 more source

Adapted Linear Binning Method to Assess Pulmonary Ventilation and Perfusion in Children Using Lung Matrix Pencil Decomposition (MP)‐MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To adapt and validate a linear binning technique, developed for hyper‐polarized 129Xe MRI, for functional lung MRI with matrix‐pencil decomposition (MP)‐MRI. Methods First, a dedicated normalization was applied to the perfusion‐weighted and the ventilation‐weighted map histograms.
Marion Curdy, Carmen Streibel, Oliver Bieri, Elisabeth Kieninger, Florian Wyler, Lukas Ebner, Grzegorz Bauman, Philipp Latzin   +7 more
wiley   +1 more source

Continuous Respiratory Oscillometry in Pediatric Laparoscopic Surgery—The COMET Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Laparoscopic appendectomy is the accepted surgical approach for appendicitis in centers worldwide. Laparoscopic surgery requires the creation of a pneumoperitoneum to facilitate surgical access. Laparoscopic surgery affects the respiratory mechanics of patients under general anesthesia.
Neil Hauser, Emanuela Zannin, Julie Nguyen, Anwen Taplin, Sara Vigevani, David Sommerfield, Raffaele Dellaca, R. Nazim Khan, Aine Sommerfield, Britta S. von Ungern‐Sternberg   +9 more
wiley   +1 more source

Secondary Immunodeficiency and Non-cystic Fibrosis Bronchiectasis [PDF]

Tuberculosis and Respiratory Diseases
Bronchiectasis is a chronic respiratory disease characterized by abnormal dilation of the bronchi that causes cough, sputum, and recurrent infections. As it may be associated with various respiratory or systemic diseases, a critical aspect of managing ...
Sungmin Zo, Ji-Yong Moon, Kyung Hoon Min, Hyun Lee   +3 more
doaj   +1 more source

Bronchiectasis: an update

The Clinical Respiratory Journal, 2009
AbstractBackground and aims:  Bronchiectasis is defined as an abnormal and irreversible dilatation of the bronchi, often associated with chronic productive cough, airway obstruction, and recurrent infections.Methods:  MEDLINE data from 1978 to November 2008 was analysed.
M. Pappalettera, S. Aliberti, P. Castellotti, RUVOLO, LEONARDO, GIUNTA, VALERIA, F. Blasi   +5 more
openaire   +3 more sources

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

High‐Flow Nasal Oxygen in Early Home Pulmonary Rehabilitation for Exertional Hypoxaemia: A Pilot Randomised Feasibility Trial

Respirology, EarlyView.
Summary This pilot randomised feasibility trial evaluated the feasibility and acceptability of early, intensive home‐based pulmonary rehabilitation (PR) and high‐flow nasal oxygen (HFO) during exercise in patients with exertional hypoxaemia post‐hospitalisation. Early home‐based PR was feasible and safe.
Yingjuan Mok, Jing Wen Foong, Hang Siang Wong, Edwin Chan Shih‐Yen, Norasyikin Hassan, Piyanee Klainin‐Yobas, Li Ching Soh, Amanda Soh, Shi Hua Tan, Xuan Han Koh, Poh Choo Tan, Keith Keat Huat Wong   +11 more
wiley   +1 more source