Results 211 to 220 of about 51,706 (265)
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Bronchiectasis

Australian Journal of General Practice, 2022
Bronchiectasis is a common chronic lung disease that is prevalent in the Australian community and is a significant disease burden in the Australian Aboriginal community. It significantly affects quality of life and increases healthcare costs; however, it is poorly reported and documented.The aim of this article is to provide a comprehensive summary of ...
Erica, Subhas, Megan, Rees
openaire   +2 more sources

The economic burden of bronchiectasis: a systematic review.

Chest, 2023
BACKGROUND Bronchiectasis, a previously neglected condition, now has renewed research interest. There are few systematic reviews that have reported on the economic and societal burden of bronchiectasis in adults, but none in children.
Jack Roberts   +9 more
semanticscholar   +1 more source

Bronchiectasis

Chest, 2019
Bronchiectasis is an important clinical syndrome because of its increasing prevalence, substantial economic burden on health care, and associated morbidity. Until recently, the disease was considered an orphan and essentially neglected from a therapeutic standpoint, but many recent advances have been made in the field.
Pamela J, McShane, Gregory, Tino
openaire   +2 more sources

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study.

The Lancet Respiratory Medicine, 2021
BACKGROUND Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are no established therapies that directly target neutrophilic inflammation because little is understood of the underlying mechanisms leading to severe disease ...
Holly R. Keir   +22 more
semanticscholar   +1 more source

Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations.

The Lancet Respiratory Medicine, 2021
Bronchiectasis refers to both a clinical disease and a radiological appearance that has multiple causes and can be associated with a range of conditions.
S. Aliberti   +33 more
semanticscholar   +1 more source

Bronchiectasis in Childhood

Clinics in Chest Medicine, 2022
Bronchiectasis is one of the diagnostic entities in the spectrum of pediatric chronic wet cough, causing significant morbidity and mortality. The pathobiology involves a vicious cycle of repeated infections, airway inflammation, dysregulated immunity, and tissue remodeling, resulting in impaired airway clearance, destruction of structural elements ...
Goyal, Vikas, Chang, Anne B.
openaire   +5 more sources

Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis.

New England Journal of Medicine
BACKGROUND In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP-1), targets neutrophil serine proteases, key ...
James D. Chalmers   +17 more
semanticscholar   +1 more source

European Respiratory Society clinical practice guideline for the management of adult bronchiectasis

European Respiratory Journal
Background Bronchiectasis is a common lung condition associated with wide range of infectious, immunological, autoimmune, allergic and genetic conditions.
J. D. Chalmers   +29 more
semanticscholar   +1 more source

Bronchiectasis

New England Journal of Medicine, 2002
Bronchiectasis is a chronic suppurative respiratory disease of declining prevalence but continuing morbidity due to recurrent respiratory infections and bronchial bleeding. Literature was reviewed through a Medline search for the past 4 years. Almost all reports are retrospective case summaries. This review focuses on the clinical assessment, stressing
openaire   +3 more sources

Neutrophilic inflammation in bronchiectasis

European Respiratory Review
Noncystic fibrosis bronchiectasis, hereafter referred to as bronchiectasis, is a chronic, progressive lung disease that can affect people of all ages. Patients with clinically significant bronchiectasis have chronic cough and sputum production, as well ...
James D. Chalmers   +6 more
semanticscholar   +1 more source

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