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Baseline characteristics of patients in the Chinese Bronchiectasis Registry (BE-China): a multicentre prospective cohort study.

The Lancet Respiratory Medicine
BACKGROUND Bronchiectasis is a disease with a global impact, but most published data come from high-income countries. We aimed to describe the clinical characteristics of patients with bronchiectasis in China.
Jin-fu Xu   +34 more
semanticscholar   +1 more source

Non-Cystic Fibrosis Bronchiectasis in Adults: A Review.

Journal of the American Medical Association (JAMA)
Importance Non-cystic fibrosis (CF) bronchiectasis is a chronic lung condition caused by permanent bronchial dilatation and inflammation and is characterized by daily cough, sputum, and recurrent exacerbations. Approximately 500 000 people in the US have
Alan F. Barker, Elham Karamooz
semanticscholar   +1 more source

Rethinking bronchiectasis as an inflammatory disease.

The Lancet Respiratory Medicine
Bronchiectasis is understood to be the result of a complex interaction between infection, impaired mucociliary clearance, inflammation, and lung damage. Current therapeutic approaches to bronchiectasis are heavily focused on management of infection along
M. Long   +3 more
semanticscholar   +1 more source

Pathophysiology of Chronic Bronchial Infection in Bronchiectasis.

Archivos de Bronconeumologia, 2022
Bronchiectasis is a complex and heterogeneous disease. Its pathophysiology is poorly understood, but chronic bronchial infection plays an important role in its natural history, and is associated with poor quality of life, more exacerbations and increased
Belén Solarat   +5 more
semanticscholar   +1 more source

A Double-blind Randomized Placebo-controlled Phase-3 Trial of Tobramycin Inhalation Solution in Adults with Bronchiectasis with Pseudomonas aeruginosa Infection.

Chest, 2022
BACKGROUND Few large-scale studies demonstrated the efficacy of tobramycin nebulization in bronchiectasis. We evaluated the efficacy and safety of nebulized tobramycin inhalation solution (TIS) in adults with bronchiectasis with Pseudomonas aeruginosa ...
W. Guan   +19 more
semanticscholar   +1 more source

Bronchiectasis

Chest, 2008
Bronchiectasis, which was once thought to be an orphan disease, is now being recognized with increasing frequency around the world. Patients with bronchiectasis have chronic cough and sputum production, and bacterial infections develop in them that result in the loss of lung function.
openaire   +2 more sources

Bronchiectasis

Internal Medicine Journal, 2006
AbstractBronchiectasis is generally classified into cystic fibrosis and non‐cystic fibrosis bronchiectasis. This review article describes non‐cystic fibrosis bronchiectasis in adults. Bronchiectasis can be considered a heterogeneous condition characterized by irreversible airway dilatation with chronic bronchial infection/inflammation.
P, King   +3 more
openaire   +2 more sources

Airway clearance management in people with bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)

European Respiratory Journal
Graphical Abstract Summary of the study. EMBARC: European Multicentre Bronchiectasis Audit and Research Collaboration; BSI: bronchiectasis severity index; QoL-B-Resp: Quality of Life Questionnaire–Bronchiectasis Respiratory symptoms; ACT: airway ...
A. Spinou   +37 more
semanticscholar   +1 more source

Bronchiectasis

Current Opinion in Infectious Diseases, 2001
Bronchiectasis is a structural derangement of the bronchial wall that is characterized by airway dilatation and bronchial wall thickening. As a result of this abnormality, chronic inflammation and secondary microbial infections occur, which cause additional damage to the bronchi.
J, Angrill, C, Agustí, A, Torres
openaire   +2 more sources

Impact of Rheumatoid Arthritis and Seropositivity on the Risk of Non-Cystic Fibrosis Bronchiectasis.

Chest
BACKGROUND Despite the coexistence of bronchiectasis and rheumatoid arthritis (RA) and the poor prognosis associated with the combination of conditions, no longitudinal studies that comprehensively evaluated whether patients with RA have a higher risk of
Hayoung Choi   +9 more
semanticscholar   +1 more source

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