Results 71 to 80 of about 84,091 (291)

Mepolizumab Effectiveness in Severe Asthma With/Without Chronic Rhinosinusitis With Nasal Polyps: Real‐World Pooled Analysis

open access: yesAllergy, EarlyView.
MEPOLYP was a pooled analysis of 1037 patients with SAEP[±]CRSwNP. Mepolizumab was associated with a reduction in CSEs, OCS use, and BEC, and improved lung function and ACT score. Over 47% of patients fulfilled ≥ 3 clinical remission criteria. When compared, there was a 30.0% incremental benefit of mepolizumab in reducing CSEs for patients with SAEP ...
Florence Schleich   +14 more
wiley   +1 more source

Lung function, symptoms and inflammation during exacerbations of non-cystic fibrosis bronchiectasis: a prospective observational cohort study. [PDF]

open access: yes, 2015
Exacerbations of non-cystic fibrosis bronchiectasis cause significant morbidity but there are few detailed data on their clinical course and associated physiological changes.
Brill, SE   +5 more
core  

Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk [PDF]

open access: yes, 2020
Background and Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. COPD is expensive to treat, whereas the quality of care is difficult to evaluate due to the high prevalence of multi ...
Chukmaitov, Askar   +3 more
core   +1 more source

Mortality in young adults following in utero and childhood exposure to arsenic in drinking water. [PDF]

open access: yes, 2012
BackgroundBeginning in 1958, the city of Antofagasta in northern Chile was exposed to high arsenic concentrations (870 µg/L) when it switched water sources. The exposure abruptly stopped in 1970 when an arsenic-removal plant commenced operations.
Ferreccio, Catterina   +5 more
core   +1 more source

Effect of radiological extent and severity of bronchiectasis on pulmonary function

open access: yesMultidisciplinary Respiratory Medicine, 2011
Background The aim of this study was to ascertain the effect of the extent and severity of bronchiectasis as determined with high-resolution computed tomography (HRCT) on lung function in patients with pure bronchiectasis, bronchiectasis and asthma, and ...
Habesoglu Mehmet A   +3 more
doaj   +1 more source

The microbiome in bronchiectasis [PDF]

open access: yesEuropean Respiratory Review, 2019
Bronchiectasis is increasing in prevalence worldwide, yet current treatments available are limited to those alleviating symptoms and reducing exacerbations. The pathogenesis of the disease and the inflammatory, infective and molecular drivers of disease progression are not fully understood, making the development of novel treatments challenging ...
Richardson, Hollian   +3 more
openaire   +5 more sources

A 20‐year case‐series of distal intestinal obstruction syndrome at a state‐wide cystic fibrosis service

open access: yesANZ Journal of Surgery, EarlyView.
Radiological features of Distal Intestinal Obstruction Syndrome (DIOS): (A) Abdominal X‐ray (AXR) demonstrating limited sensitivity in diagnosing DIOS. (B) Coronal computed tomography (CT) confirming DIOS with characteristic findings of faecal loading, mural striation, and pericolonic fat stranding.
Chen Lew   +6 more
wiley   +1 more source

The diagnosis and treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease and chronic bronchitis. [PDF]

open access: yes, 2010
The syndrome of chronic obstructive pulmonary disease (COPD) consists of chronic bronchitis (CB), bronchiectasis, emphysema, and reversible airway disease that combine uniquely in an individual patient.
Albertson, Timothy E   +2 more
core  

Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]

open access: yes, 2018
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina   +10 more
core   +1 more source

Physiological Control of Realheart Total Artificial Heart

open access: yesArtificial Organs, EarlyView.
This study evaluates the Realheart Total Artificial Heart's preload‐based physiological controller, which dynamically adjusts heart rate and stroke volume to mimic the heart's natural responses during sleep, rest, and exercise using a hybrid mock circulation loop of the cardiovascular system.
Emanuele Perra   +7 more
wiley   +1 more source

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