Results 121 to 130 of about 84,064 (299)

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Reactive type II pneumocytes in bronchoalveolar lavage fluid. [PDF]

, 2004
Reactive type II pneumocytes in bronchoalveolar lavage fluid. Linssen KC, Jacobs JA, Poletti VE, van Mook W, Cornelissen EI, Drent M. Department of Medical Microbiology, University Hospital Maastricht, Maastricht, The Netherlands.
Poletti, V.E., van Mook, W., Jan A. Jacobs, Marjolein Drent, Elisa I. M. Cornelissen, Jacobs, J.A., Drent, M., Walther van Mook, Venerino E. Poletti, Cornelissen, E.I., Kitty C. F. M. Linssen, Linssen, K.C.   +11 more
core   +1 more source

Rickettsia felis Pulmonary Infection Detected via Metagenomic Next-Generation Sequencing in a Clonorchiasis Patient: A Case Report

Infection and Drug Resistance
Sha Wen,* Jing-Jing Zeng,* Ying Li Department of Critical Care Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital, Shenzhen, People’s Republic of China*These authors contributed equally to this ...
Wen S, Zeng JJ, Li Y
doaj  

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, EarlyView.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

Electronic cell counting to measure total cell numbers in bronchoalveolar lavage fluid [PDF]

, 1994
Cell counting of bronchoalveolar lavage (BAL) fluid is performed manually in routine practice. This has both methodological and inherent errors; however, the accuracy and suitability of automated counting devices have been questioned.
Ennis, Madeleine, Stanford, C.F., Heaney, Liam, Mckirgan, J.   +3 more
core  

The role of eCyPA as an inflammatory biomarker for predicting 28-day mortality in ARDS patients

Respiratory Research
Background Acute respiratory distress syndrome (ARDS) is the primary manifestation of systemic inflammatory response syndrome in the lungs. Extracellular cyclophilin A (eCyPA) as a novel inflammatory marker, this study aims to investigate the expression ...
Juan Chen, Xue Dai, Jing Lv, Meijun Liu, Ewan C. Goligher, Wang Deng   +5 more
doaj   +1 more source

Effects of fluticasone propionate inhalation on levels of arachidonic acid metabolites in patients with chronic obstructive pulmonary disease

Mediators of Inflammation, 2001
Background: In smoking COPD patients the bronchoalveolar lavage (BAL) fluid contains high numbers of inflammatory cells. These cells might produce arachidonic acid (AA) metabolites, which contribute to inflammation and an increased bronchomotor tone.
Gert T. Verhoeven, Ingrid M. Garrelds, Henk C. Hoogsteden, Freek J. Zijlstra   +3 more
doaj   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source