Results 131 to 140 of about 84,064 (299)

DIAGNOSTIC ACCURACY OF GENEXPERT ASSAY AND COMPARISON WITH SMEAR AFB ON BRONCHIAL WASHINGS IN SPUTUM NEGATIVE SUSPECTED PULMONARY TUBERCULOSIS

Pakistan Armed Forces Medical Journal, 2019
Objective: To determine diagnostic accuracy of GeneXpert Assay and compare it with smear microscopy for AFB in terms of sensitivity, specificity on bronchial washings/bronchoalveolar lavage samples in sputum smear negative suspected tuberculosis ...
Mahmood Iqbal Malik, Taymmia Ejaz, Jamal Ahmed, Komal Arshad, Yousaf Jamal, Zeenat Zohfreen   +5 more
doaj  

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source

Baseline Neutrophil‐To‐Lymphocyte Ratio as a Risk Stratification Marker for Severe Checkpoint Inhibitor Pneumonitis in Patients With Non‐Small Cell Lung Cancer: A Two‐Cohort Study With Retrospective Discovery and Prospective Validation

Respirology, EarlyView.
The association between baseline neutrophil‐to‐lymphocyte ratio (NLR) and severe checkpoint inhibitor pneumonitis (CIP) was analyzed in discovery retrospective and validation prospective cohorts. Higher baseline NLR (≥ 4.75) was associated with increased severe CIP incidence in both cohorts.
Tetsu Hirakawa, Kakuhiro Yamaguchi, Shun Takao, Nobuhiro Kanaji, Naoko Matsumoto, Kozue Miyazaki, Tamio Okimoto, Chihiro Ando, Hisao Higo, Masaaki Yanai, Koji Kurose, Yasunari Nagasaki, Masako Watanabe, Kosuke Oyama, Yuko Toyoda, Yoshihiro Taguchi, Shimpei Tada, Kiyofumi Shimoji, Shinjiro Sakamoto, Yasushi Horimasu, Takeshi Masuda, Taku Nakashima, Hiroshi Iwamoto, Hironobu Hamada, Noboru Hattori   +24 more
wiley   +1 more source

Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storage [PDF]

, 2010
Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term ...
LJ Berry (14457408), B Sheil (13372077), L Garratt (13373232), PD Sly (14453628)   +3 more
core  

Comparing the Effects of Microplastics From Conventional Cigarette Butts and Heated Tobacco Device: The Role of UV‐Induced Aging

Environmental Toxicology, EarlyView.
ABSTRACT Despite the widespread presence of cigarette butts in the environment, the potential toxicological effects posed by microplastics (MPs) derived from them remain poorly understood. In this study, we compared the effects of MPs from conventional cigarette butts (cellulose acetate) and heated tobacco devices (cellulose acetate and polylactic acid
Andraž Dolar, Veno Kononenko, Valentina Perc, Damjana Drobne, Gabriela Kalčíková, Jernej Imperl, Tina Skalar, Ula Rozman, Branka Mušič, Anita Jemec Kokalj   +9 more
wiley   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, EarlyView.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

[Analysis of cells and proteins in bronchoalveolar lavage fluid].

Nihon Kyobu Shikkan Gakkai zasshi, 1996
We studied cells and proteins in bronchoalveolar lavage fluid examined at the First Department of Internal Medicine of Shinshu University Hospital between 1990 and 1994. The samples came from 21 healthy subjects and from 216 patients with various diseases.
Hanaoka, Masayuki, Fujimoto, Keisaku, Hayasaka, Muneharu, Kubo, Keishi, Kobayashi, Toshio, Sekiguchi, Morie, Honda, Takayuki   +6 more
openaire   +2 more sources

Specific proteins of inflammatory cells and alpha1-proteinase inhibitor in alveolar epithelial lining fluid of polytraumatized patients [PDF]

, 1991
Jochum, Marianne, Sturm, J. A.
core   +1 more source

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

Allergy, EarlyView.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata, Jaclyn W. McAlees, Julie M. Hargis, Archana Shankar, Shouxiong Huang, Senad Divanovic, Ian P. Lewkowich   +6 more
wiley   +1 more source