Results 251 to 260 of about 110,976 (348)

Dose individualisation of antibiotics in critically ill patients with inflammation: A narrative review

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3042-3053, November 2025.
Due to extensive pathophysiological changes in critically ill patients, standard dosing of antibiotics may lead to inadequate drug exposure. This is concerning, as insufficient plasma drug concentrations may lead to treatment failure, whereas excessive drug exposure may increase the risk of toxic adverse events.
Sarah Dräger   +12 more
wiley   +1 more source

Baseline Characteristics of Bronchial Secretions and Bronchoalveolar Lavage Fluid in Patients with Ventilator-Associated Pneumonia. [PDF]

open access: yesMicroorganisms
Stamatiou R   +7 more
europepmc   +1 more source

Clinical application of single‐cell RNA sequencing in disease and therapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 11, November 2025.
This review provides a comprehensive overview of the application of scRNA‐seq in revisiting the somatic cell evolutions in human diseases, as well as in biomarker discovery and drug development. Abstract Background The emergence of single‐cell RNA sequencing (scRNA‐seq) technology has revolutionized our capacity to study cell functions in complex ...
Aisha Shigna Nadukkandy   +3 more
wiley   +1 more source

A Review of Antioxidant Activity, Anti‐Inflammatory Properties, Apoptosis‐Regulatory Effects, and Immune System Modulation of Juglans regia L. (Walnut)

open access: yesFood Science &Nutrition, Volume 13, Issue 11, November 2025.
J. regia L. represents a valuable natural source of antioxidants, anti‐inflammatory agents, apoptosis‐regulatory agents, and immunomodulators. The walnut‐rich phytochemical profile contributes to its therapeutic potential in combating oxidative stress and inflammation, regulating apoptosis and immune responses.
Mahboobeh Ghasemzadeh Rahbardar   +2 more
wiley   +1 more source

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

open access: yesJournal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold   +23 more
wiley   +1 more source

Single-Cell Landscape of Bronchoalveolar Lavage Fluid Identifies Specific Neutrophils during Septic Immunosuppression. [PDF]

open access: yesAdv Sci (Weinh)
Shen R   +16 more
europepmc   +1 more source

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