Results 81 to 90 of about 127,822 (311)

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing

Frontiers in Microbiology, 2018
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been ...
Magnus Paulsson, Karlhans F. Che, Jonas Ahl, Johan Tham, Linda Sandblad, Margaretha E. Smith, Ingemar Qvarfordt, Yu-Ching Su, Anders Lindén, Anders Lindén, Kristian Riesbeck   +10 more
doaj   +1 more source

Recent advances in isothermal amplification techniques coupled with clustered regularly interspaced short palindromic repeat/Cas systems

Interdisciplinary Medicine, EarlyView.
Abstract Isothermal amplification (IA) techniques have emerged as promising alternatives to polymerase chain reaction (PCR), enabling rapid and efficient nucleic acid amplification at constant temperatures. Meanwhile, clustered regularly interspaced short palindromic repeat (CRISPR)/Cas‐based technology has revolutionized molecular diagnostics by ...
Miao Liu, Yajun Hou, Yuhang Cheng, Ziyun Li, Jiawei Zeng, Li Li, Jinyong Luo, Bo Shen   +7 more
wiley   +1 more source

Characterization of the innate immune response to chronic aspiration in a novel rodent model

Respiratory Research, 2007
Background Although chronic aspiration has been associated with several pulmonary diseases, the inflammatory response has not been characterized. A novel rodent model of chronic aspiration was therefore developed in order to investigate the resulting ...
Lin Shu S, Yoon Yonghan, Cantu Edward, Hsieh Chong-Chao, Li Bin, Hartwig Matthew G, Lee Sean M, Appel James Z, Parker William, Davis R Duane   +9 more
doaj   +1 more source

Systematic Review and Meta-Analysis of Detecting Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosing Invasive Aspergillosis

PLoS ONE, 2012
Background Bronchoalveolar lavage (BAL) galactomannan (GM) assay has been used for diagnosing invasive aspergillosis (IA). We aimed to derive a definitive estimate of the overall accuracy of BAL-GM for diagnosing IA.
Mingxiang Zou, Lanhua Tang, Shushan Zhao, Zijin Zhao, Luyao Chen, Peng Chen, Zebing Huang, Jun Li, Lizhang Chen, Xuegong Fan   +9 more
semanticscholar   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Cell Recovery in Bronchoalveolar Lavage Fluid in Smokers Is Dependent on Cumulative Smoking History

PLoS ONE, 2012
Background Smoking is a risk factor for various lung diseases in which BAL may be used as a part of a clinical investigation. Interpretation of BAL fluid cellularity is however difficult due to high variability, in particular among smokers. In this study
R. Karimi, G. Tornling, J. Grunewald, A. Eklund, C. Sköld   +4 more
semanticscholar   +1 more source

The Complex Role of IL‐13 in Bullous Pemphigoid: New Insights From a Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Bullous pemphigoid (BP) is the most common autoimmune blistering skin disease, primarily affecting the elderly. The role of interleukin‐13 (IL‐13) in BP pathogenesis remains unclear, particularly regarding its potential as a therapeutic target.
Marwan Dawood, Zenab Ali Saleh, Ilanit Boyango, Orna Mirmovich Morvay, Salih Mishlab, Ziad Khamaysi, Emily Avitan‐Hersh   +6 more
wiley   +1 more source

Fungi identified via next-generation sequencing in bronchoalveolar lavage fluid among patients with COVID-19: a retrospective study

European Journal of Medical Research
Background The epidemiology of fungi identified via next-generation sequencing in bronchoalveolar lavage fluid among patients with COVID-19 is unknown.
Xiaobo Yang, Xuehui Gao, Hongling Zhang, Jiqian Xu, You Shang   +4 more
doaj   +1 more source

Anatomical distribution of bronchoalveolar lavage fluid as assessed by digital subtraction radiography. [PDF]

, 1987
C A Kelly, C J Kotre, Chris Ward, D.J. Hendrick, E. Haydn Walters   +4 more
openalex   +1 more source