Results 81 to 90 of about 110,976 (348)

Comparison of the adherence of nontypeable haemophilus influenzae to lung epithelial cells

BMC Infectious Diseases
Objective Nontypeable Haemophilus influenzae (NTHi) plays an important role in respiratory tract infections, and adherence to lung epithelial cells is the first step in lung infections.
Yuwei Rong, Zihao Liu, Heping Wang, Zuguo Zhao   +3 more
doaj   +1 more source

気管支肺胞洗浄液中リンパ球増多と患者年齢およびIgE系アレルギー反応との関連について [PDF]

, 1993
The proportion and number of lymphocytes in the airways were analyzed in 15 patients with a high proportion of lymphocytes in bronchoalveolar lavage (BAL) fluid (more than 30%) and in 17 patients with less than 20% of BAL lymphocytes. 1.
Kimura, Ikuro, Kitani, Hikaru, Mifune, Takashi, Mitsunobu, Fumihiro, Tanizaki, Yoshiro   +4 more
core   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Bronchoalveolar lavage proteomics in exacerbation of bronchiectasis

BMC Pulmonary Medicine
Background The molecular pathophysiology underlying the development of bronchiectasis with exacerbation at the proteomic level has not been clarified using bronchoalveolar lavage fluid samples.
Ju Yeon Lee, Jiyoul Yang, Jin Young Kim, Yeji Do, Min-Sik Kim, Dong Eun Kye, Geonhui Min, In-Sook Jeon, Eung-Gook Kim, Joong Kook Choi, Minjae Choi, Hyun Lee, Bumhee Yang   +12 more
doaj   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

Advanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun, Xiya Li, Shenjia Gao, Yi Jiang, Xinyi Wu, Zhaoyuan Chen, Han Wu, Qing Hua, Rui Zu, Huaijiang Xiang, Ronen Ben‐Ami, Changhong Miao, Li Tan, Ying Li, Jun Wang, Wankun Chen   +15 more
wiley   +1 more source

Bronchoalveolar lavage fluid lymphocytosis in 104 dogs (2006‐2016)

Journal of Veterinary Internal Medicine, 2019
Background Bronchoalveolar lavage (BAL) fluid cytology and culture are used to characterize respiratory diseases in dogs. Little is known about disorders associated with increased numbers of lymphocytes in BAL fluid.
Lynelle R. Johnson, William Vernau
doaj   +1 more source

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

Advanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang, Ri Tang, Yang Zhou, Jinquan Zhang, Shuya Mei, Yawen Peng, Xi Huang, Shunpeng Xing, Yuan Gao, Qiaoyi Xu, Zhengyu He   +10 more
wiley   +1 more source

Galactomannan antigen assay from bronchoalveolar lavage fluid in diagnosis of invasive pulmonary aspergillosis in intensive care units patients

Advanced Biomedical Research, 2014
Background : Invasive pulmonary aspergillosis (IPA) is an important infection in critically ill patients including patients of intensive care units (ICU).
Farzin Khorvash, Mohsen Meidani, Leila Babaei, Saeed Abbasi, Behrooz Ataei, Majid Yaran   +5 more
doaj   +1 more source

Cysteine cathepsins in human silicotic bronchoalveolar lavage fluids

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006
Mature, active cysteine cathepsins (CPs) were identified in human inflammatory bronchoalveolar lavage fluid (BALF) supernatants from patients suffering from silicosis by both western blot and surface plasmon resonance analyses. BALFs are not a reservoir of activatable proforms, since no autocatalytic maturation at acidic pH occurs.
Perdereau, Céline, Godat, Emmanuel, Maurel, Marie-Christine, Hazouard, Eric, Diot, Elisabeth, Lalmanach, Gilles   +5 more
openaire   +4 more sources