Results 111 to 120 of about 42,854 (297)

Dermal Substitutes for Clinical Management of Severe Burn Injuries: Current and Future Perspectives

Advanced Therapeutics, Volume 8, Issue 3, March 2025.
This review provides an updated insight into various commercialized dermal substitutes, current skin tissue engineering research, and clinical gaps in the management of severe burn injuries. Potential avenues for the development of the next‐generation dermal substitutes using the latest tissue engineering approaches aimed at improving overall tissue ...
Van Vo, Hanif Haidari, Allison J. Cowin, Marcus Wagstaff, Bronwyn Dearman, Zlatko Kopecki   +5 more
wiley   +1 more source

Factors Associated with Poor Asthma Control among Sudanese Patients Attending Atbara Teaching Hospital in Sudan

Sudan Journal of Medical Sciences
Objective: To identify factors associated with poor bronchial asthma control in patients attending Atbara Teaching Hospital, Sudan, in 2020. Methods: This was an analytical, descriptive, cross-sectional hospital-based study conducted at the Atbara ...
Hadeel Kareem Aladdin, Sufian Khalid Mohammed Noor, Amro Mohamed Fagir Farah, Sara Elamin Bushara   +3 more
doaj   +1 more source

The effect of the tachykinin NK2 receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in asthmatics

Therapeutic Advances in Respiratory Disease, 2009
Objective: We previously reported that the nonpeptide tachykinin NK 2 receptor antagonist SR48968 (saredutant) significantly inhibits neurokinin A-induced bronchoconstriction in patients with asthma. MEN11420 (nepadutant) is a bicyclic peptide tachykinin
Venessa Schelfhout, Veerle Van De Velde, Carlo Maggi, Romain Pauwels, Guy Joos   +4 more
doaj   +1 more source

Primary Hepatic Neuroendocrine Carcinoma Associated With Carcinoid Syndrome and Pellagra: A Case Report

Liver International Communications, Volume 6, Issue 1, March 2025.
ABSTRACT Carcinoid tumours are slow‐growing neuroendocrine neoplasms mainly affecting the gastrointestinal tract, the respiratory tree, ovaries and kidneys. Approximately 20% of patients with carcinoid tumour are affected by carcinoid syndrome, characterised by chronic diarrhoea and/or flushing in the presence of systemically elevated levels of ...
Abdelmounem Eltayeb Abdo, Susanna Caminada, Salma Barakat Mudawi, Sami Medani Abd Elwahab, Ahmed Rafei, Christos Vosinakis, Damiano Pizzol, Lee Smith   +7 more
wiley   +1 more source

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]

, 1994
Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD, Griffiths-Johnson, DA, Hsuan, JJ, Jose, PJ, Moqbel, R, Totty, NF, Truong, O, Walsh, DT, Williams, TJ   +8 more
core   +1 more source

Small airway dysfunction is associated to excessive bronchoconstriction in asthmatic patients

Respiratory Research, 2014
BackgroundWe investigated whether a relationship between small airways dysfunction and bronchial hyperresponsiveness (BHR), expressed both in terms of ease of airway narrowing and of excessive bronchoconstriction, could be demonstrated in asthma ...
V. Alfieri, M. Aiello, R. Pisi, P. Tzani, E. Mariani, E. Marangio, D. Olivieri, G. Nicolini, A. Chetta   +8 more
semanticscholar   +1 more source

Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice

JCI Insight, 2022
Obesity-induced asthma responds poorly to all current pharmacological interventions, including steroids, suggesting that classic, eosinophilic inflammation is not a mechanism.
Gina N. Calco, Jessica N. Maung, David B. Jacoby, Allison D. Fryer, Zhenying Nie   +4 more
doaj   +1 more source

Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events [PDF]

, 2009
Epidemiological evidence has suggested a link between beta(2)-agonists and increased asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta(2)-agonists are safe ...
Altman, Anonymous, Arthurs, Aubier, Bailey, Barnes, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Beach, Bons, Boushey, Boushey, Boushey, Bousquet, Bousquet, Bousquet, Briggs, Busse, Busse, Castle, Cates, Cates, Cates Christopher, Clark, Clark, Clark, Clark, Clark, Cordier, Ducharme, Edin, Giembycz, Godard, Greenstone, Ind, Jarjour, Juniper, Kavuru, Koenig, Koopmans, Lipworth, Lundbäck, Malone, Murray, Nathan, Nathan, Nelson, Nelson, Ni Chroinin, Ni Chroinin, Noord, Pauwels, Pauwels, Pauwels, Pearce, Pearlman, Pearlman, Pedersen, Pedersen, Pederson, Rojas, Rooklin, Salpeter, Sears, Shapiro, Strand, Wallin, Walters, Walters, Weinstein   +74 more
core   +1 more source

Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation.

Lab on a Chip, 2014
Many potential new asthma therapies that show promise in the pre-clinical stage of drug development do not demonstrate efficacy during clinical trials.
Alexander P Nesmith, A. Agarwal, Megan L. McCain, K. Parker   +3 more
semanticscholar   +1 more source

Out of Breath, out of Options: Benralizumab as a Last Hope in ICU‐Treated Near‐Fatal Eosinophilic Asthma: A Case Series

Respirology Case Reports, Volume 13, Issue 3, March 2025.
This series of four patients highlights the potential role of benralizumab in treating life‐threatening asthma exacerbations driven by eosinophilic airway inflammation and underlines the need for phenotyping and timely intervention in managing such patients with near‐fatal asthma while also stressing the need for continued adherence to asthma ...
Lennart Conemans, Emel Demir, Martijn Bischoff, Frits Franssen, Sami Simons   +4 more
wiley   +1 more source