Results 131 to 140 of about 44,370 (261)

Efficacy and safety of glycopyrrolate in patients with COPD by reversibility: pooled analysis of the GEM1 and GEM2 12-week studies

open access: yesInternational Journal of COPD, 2019
Jill A Ohar,1 Alyssa Bowling,2 Thomas Goodin,2 Barry Price,2 Ayca Ozol-Godfrey,2 Sanjay Sharma,2 Shahin Sanjar2 1Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Sunovion Pharmaceuticals Inc, Marlborough, MA, USA
Ohar JA   +6 more
doaj  

First Experience With Extravascular Implantable Cardioverter‐Defibrillator Under Deep Sedation

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The Extravascular Implantable Cardioverter‐Defibrillator (EV‐ICD) utilizes a substernal lead to provide defibrillation and anti‐tachycardia pacing (ATP) while avoiding transvenous complications. General anesthesia (GA) was applied for implantation procedures in the EV‐ICD pivotal trial and is currently recommended by the ...
Nibras Soubh   +9 more
wiley   +1 more source

Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD

open access: yesInternational Journal of COPD, 2018
Colin Reisner,1,2 James Pearle,3 Edward M Kerwin,4 Earl St Rose,1 Patrick Darken1 1Pearl – a member of the AstraZeneca Group, Morristown, NJ, USA; 2AstraZeneca, Gaithersburg, MD, USA; 3California Research Medical Group, Inc., Fullerton, CA, USA ...
Reisner C   +4 more
doaj  

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy   +7 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

open access: yesExperimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts   +13 more
wiley   +1 more source

WITHIN-BREATH RESPIRATORY RESISTANCE IN CHILDREN WITH POSITIVE BRONCHODILATOR RESPONSE

open access: yes, 2022
WITHIN-BREATH RESPIRATORY RESISTANCE IN CHILDREN WITH POSITIVE BRONCHODILATOR ...
A Chacko (13367877)   +5 more
core  

Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig   +4 more
wiley   +1 more source

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley   +1 more source

Bronchodilator efficacy and safety of indacaterol 150 µg once daily in patients with COPD: an analysis of pooled data

open access: yes, 2011
Eugene R Bleecker1, Thomas Siler2, Roger Owen3, Benjamin Kramer41Center for Genomics and Personalized Medicine Research and Translational Medicine Institute, Wake Forest University Health Sciences, Winston-Salem, NC, USA; 2Midwest Chest Consultants ...
Siler T, Bleecker ER, Kramer B, Owen R
core  

Observing Clinical Efficiency: A First Step to Fill a Clinical Education Gap in Emergency Medicine

open access: yesAEM Education and Training, Volume 10, Issue 5, October 2026.
ABSTRACT Background Emergency medicine (EM) demands high levels of clinical efficiency in dynamic clinical environments, yet few tools exist to support educators in assessing and coaching residents on efficiency behaviors. Objective To develop and pilot an observational domain‐based assessment to characterize and assess individual resident clinical ...
Michael C. Overbeck   +6 more
wiley   +1 more source

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