Results 121 to 130 of about 57,781 (271)

Bronchodilator efficacy of extrafine glycopyrronium bromide: the Glyco 2 study

International Journal of COPD, 2017
Dave Singh,1 Mario Scuri,2 Sara Collarini,2 Stefano Vezzoli,2 Fabrizia Mariotti,2 Annamaria Muraro,2 Daniela Acerbi2 1Medicines Evaluation, University Of Manchester, University Hospital of South Manchester, Manchester, UK; 2Global Clinical Development ...
Singh D, Scuri M, Collarini S, Vezzoli S, Mariotti F, Muraro A, Acerbi D   +6 more
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Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig, Kirsten Stewart, Chris RuiWen Kuo, Rory Chan, Brian Lipworth   +4 more
wiley   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

Perinatal Exposures Are Related to Atopic Symptom Development in Early Childhood

Clinical &Experimental Allergy, EarlyView.
Gina J. van Beveren, Nynke L. Harschel, Erik Tieken, Sjoerd M. Euser, Frans B. Plötz, Wouter J. de Waal, Ivo van der Lee, Suzanne W. J. Terheggen‐Lagro, Marlies A. van Houten, Debby Bogaert   +9 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Management of Asthma and COPD Exacerbations in Adults in the ICUKey PointsClinical QuestionClinical Question

CHEST Critical Care
Severe, life-threatening asthma and COPD exacerbations are managed commonly in the ICU and are associated with significant morbidity and mortality. It is important to understand the commonalities and differences in the diagnosis and management of these ...
Stephen A. Mein, MD, Michael C. Ferrera, MD   +1 more
doaj   +1 more source

Analysis of Pulsatile Vessel Expansion in Healthy, COPD‐ and PH‐Patients Using Dynamic Vessel Segmentation in Free‐Breathing Lung MRI

Journal of Magnetic Resonance Imaging, Volume 63, Issue 5, Page 1420-1432, May 2026.
ABSTRACT Background The pulsatile expansion of pulmonary vessels carries dynamic cardiopulmonary information that may reveal disease earlier than structural changes alone. Purpose To test (i) intra‐ and inter‐scan repeatability of dynamic vessel metrics in healthy subjects, and (ii) whether chronic obstructive pulmonary disease (COPD) and postcapillary
Julian Glandorf, Marius M. Klein, Filip Klimeš, Agilo Luitger Kern, Marcel Gutberlet, Jens M. Hohlfeld, Marius M. Hoeper, Karen M. Olsson, Frank Wacker, Jens Vogel‐Claussen, Andreas Voskrebenzev   +10 more
wiley   +1 more source

Efficacy and safety of glycopyrrolate in patients with COPD by reversibility: pooled analysis of the GEM1 and GEM2 12-week studies

International Journal of COPD, 2019
Jill A Ohar,1 Alyssa Bowling,2 Thomas Goodin,2 Barry Price,2 Ayca Ozol-Godfrey,2 Sanjay Sharma,2 Shahin Sanjar2 1Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Sunovion Pharmaceuticals Inc, Marlborough, MA, USA
Ohar JA, Bowling A, Goodin T, Price B, Ozol-Godfrey A, Sharma S, Sanjar S   +6 more
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Accelerating PREFUL MRI: Comparison of Registration Methods and Impact of Time Series Reduction

NMR in Biomedicine, Volume 39, Issue 5, May 2026.
Retrospective shortening of the PREFUL MRI acquisition showed that most parameters remained strongly correlated (≥ 77%) and regionally concordant (overlap ≥ 79%) with the 55‐s ground truth down to 30 s in healthy volunteers and COPD, except for perfusion, which was more sensitive to truncation.
A. Voskrebenzev, G. H. Pöhler, F. Klimeš, M. M. Klein, R. A. Müller, F. Wacker, J. M. Hohlfeld, J. Vogel‐Claussen   +7 more
wiley   +1 more source

Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD

International Journal of COPD, 2018
Colin Reisner,1,2 James Pearle,3 Edward M Kerwin,4 Earl St Rose,1 Patrick Darken1 1Pearl – a member of the AstraZeneca Group, Morristown, NJ, USA; 2AstraZeneca, Gaithersburg, MD, USA; 3California Research Medical Group, Inc., Fullerton, CA, USA ...
Reisner C, Pearle J, Kerwin EM, St Rose E, Darken P   +4 more
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