Results 161 to 170 of about 68,751 (311)

Fentanyl Compromises Lower‐Airway Mechanics and Naloxone Triggers a Transient Mechanical Overshoot

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the leading cause of death following opioid overdose, due to its effects on central rhythm generation, and airway and thoracic constriction. While the effects on rhythm generation have been well documented, the effects of fentanyl on airway constriction are less well understood. We tested the
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Madeline M. Johnson, Nicholas J. Burgraff   +4 more
wiley   +1 more source

Lack of correlation between bronchoconstrictor response and bronchodilator response in a population-based study

, 1997
Bronchodilator and bronchoconstrictor responsiveness have been considered physiological opposites in patients with obstructive airways disease, Provocation challenges have been replaced by bronchodilator tests in the assessment of cases of severe airways
Postma, DS, Douma, WR, Koeter, GH, de Gooijer, A, Schouten, JP, Weiss, ST, Rijcken, B   +6 more
core   +1 more source

Regional lung response to bronchodilator reversibility testing determined by electrical impedance tomography in chronic obstructive pulmonary disease.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2016
B. Vogt, Zhanqi Zhao, P. Zabel, N. Weiler, I. Frerichs   +4 more
semanticscholar   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Bronchodilator response as a marker of poor asthma control.

Respiratory Medicine, 2016
Enrico Heffler, C. Crimi, R. Campisi, Stefania Sichili, Giuliana Nicolosi, Morena Porto, Rossella Intravaia, M. Sberna, Maria Teresa Liuzzo, N. Crimi   +9 more
semanticscholar   +1 more source

Bronchodilator response of advanced lung function parameters depending on COPD severity

, 2016
Linnea Jarenbäck,1 Göran Eriksson,1 Stefan Peterson,2 Jaro Ankerst,1 Leif Bjermer,1 Ellen Tufvesson1 1Respiratory Medicine and Allergology, Department of Clinical Sciences Lund, Lund University, 2Regional Cancer Center South, Skåne ...
Eriksson G, Ankerst J, Peterson S, Jarenbäck L, Tufvesson E, Bjermer L   +5 more
core  

Respiratory Biomarkers: An Opportunity for Patient‐Centric Microsampling Approach for Treatment Optimization

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Overview of patient centric microsampling approach for monitoring respiratory biomarkers for treatment optimization. Image created in BioRender. Khan, A. (2026) https://BioRender.com/17jm5cs. ABSTRACT The clinical heterogeneity of respiratory disorders emphasizes the need for personalized approaches to prevention, diagnosis, and therapy.
Ahmar Khan, Jacqueline L. Stair, Daniel Baker, Neil Spooner, Darragh Murnane   +4 more
wiley   +1 more source

Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease

International Journal of COPD, 2018
Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
doaj  

A Qualitative Exploration of Unanticipated Effects Experienced By People With Chronic Obstructive Pulmonary Disease Who Participated in Interventions Designed to Reduce Sedentary Behaviour

Health Expectations, Volume 29, Issue 3, June 2026.
ABSTRACT Introduction This study explored the lived experiences of people with chronic obstructive pulmonary disease (COPD) who participated in interventions designed to reduce the accumulation of sedentary behaviour in prolonged uninterrupted bouts. Methods Ten participants with stable COPD participated in a multi‐component intervention that spanned ...
Fiona Coll, Vinicius Cavalheri, Daniel F. Gucciardi, Kylie Hill   +3 more
wiley   +1 more source

Clinical guideline highlights for the hospitalist: Recommendations for pneumonia in hospitalized children with neurologic impairment

Journal of Hospital Medicine, Volume 21, Issue 6, Page 657-659, June 2026.
Elizabeth L. Nichols, J. Andrew Watson
wiley   +1 more source