Results 41 to 50 of about 61,454 (303)

Small airway dysfunction and flow and volume bronchodilator responsiveness in patients with chronic obstructive pulmonary disease

International Journal of COPD, 2015
Background We investigated whether a relationship between small airways dysfunction and bronchodilator responsiveness exists in patients with chronic obstructive pulmonary disease (COPD). Methods We studied 100 (20 female; mean age: 68±10 years) patients
R. Pisi, M. Aiello, A. Zanini, P. Tzani, D. Paleari, E. Marangio, A. Spanevello, G. Nicolini, A. Chetta   +8 more
semanticscholar   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

British Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl, Rod Hughes, Joachim Almquist, David Close, Jukka Mäenpää, Ulrika Tehler, Tina Jellesmark Jensen, Szilárd Nemes, Anne‐Kristina Mercier, Zala Jevnikar, Pablo Forte Soto, Dave Singh   +11 more
wiley   +1 more source

Effects of Oral Doxofylline and Procaterol on Chronic Obstructive Pulmonary Disease: A Randomized Crossover Study

Medical Sciences
Background: Oral bronchodilators may serve as an adjunctive therapy in patients with chronic obstructive pulmonary disease (COPD). This study aimed to evaluate the effects of oral doxofylline and oral procaterol on lung function and clinical symptoms in ...
Narongkorn Saiphoklang, Sarawut Panichaporn, Thiravit Siriyothipun, Pitchayapa Ruchiwit   +3 more
doaj   +1 more source

Evaluation of oral health of 6 to 10-year-old asthmatic children receiving bronchodilator through inhaler

Indian Journal of Dental Research, 2019
Aim: The aim of this study was to evaluate the oral health status in 6 to 10-year-old asthmatic children receiving bronchodilator (salbutamol, salmeterol, etc.) through inhaler and compare them with nonasthmatic healthy children. Settings and Design: The
Sudhir Kumar, Namita Kalra, Rishi Tyagi, M M A Faridi, Amit Khatri, V N V Satish   +5 more
doaj   +1 more source

Beta‐blockers in patients with heart failure with reduced ejection fraction and concomitant chronic obstructive pulmonary disease: Cardiovascular and respiratory outcomes

European Journal of Heart Failure, EarlyView.
In total, 5084 patients from Swedish registries with both heart failure (HF) with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) were included. Confounding was handled by overlap weighting based on propensity scores for beta‐blocker use. Patients were followed up for 5 years, or until death, emigration from Sweden or
Benedikt N. Beer, Lina Benson, Christian Basile, Benedikt Schrage, Peter Moritz Becher, Stefan Blankenberg, Paulus Kirchhof, Barna Szabó‐Söderberg, Marco Metra, Anne Lindberg, Egidio Imbalzano, Giuseppe M. C. Rosano, Patric Karlström, Peter G.M. Mol, Raffaele Scorza, Lars H. Lund, Felix Lindberg, Gianluigi Savarese   +17 more
wiley   +1 more source

Chest Pain Relieved with a Bronchodilator or Other Asthma Drugs

Allergology International, 2009
Background: Although many patients who experience chest pain or pressure consult their physicians, unfortunately a large number of them do not, and consequently they remain undiagnosed and untreated.
Hirokazu Taniguchi, Kenta Kanbara, Kiyoshi Hoshino, Saburo Izumi   +3 more
doaj   +1 more source

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Sensors, 2022
The purpose of this study was to explore the relationships between heart rate variability (HRV) and various phenotypic measures that relate to health and functional status in chronic obstructive pulmonary disease (COPD), and secondly, to demonstrate the ...
Seon-Cheol Park, Narongkorn Saiphoklang, Donghyun Jung, David Gomez, Jonathan E. Phillips, Brett A. Dolezal, Donald P. Tashkin, Igor Barjaktarevic, Christopher B. Cooper   +8 more
doaj   +1 more source

Dual bronchodilation with QVA149 versus single bronchodilator therapy: the SHINE study

European Respiratory Journal, 2013
We investigated the efficacy and safety of dual bronchodilation with QVA149 versus its monocomponents indacaterol and glycopyrronium, tiotropium and placebo in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
E. Bateman, G. Ferguson, N. Barnes, N. Gallagher, Y. Green, M. Henley, D. Banerji   +6 more
semanticscholar   +1 more source

Immunological effects of alpha‐lactalbumin‐enriched low‐protein infant formula: A randomized controlled trial

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Breast‐fed (BF) have lower risk of infections during infancy compared to those formula‐fed (FF). A higher content of alpha‐lactalbumin (α‐lac) in breast milk, which may promote a more favorable gut microbiota, could be one reason.
Ulrika T. Nilsson, Olle Hernell, Bo Lönnerdal, Lotte N. Jacobsen, Maria Nunez‐Salces, Anne S. Kvistgaard, Christina West, Pia K. Åkeson   +7 more
wiley   +1 more source

Assessment of bronchodilator responsiveness to salbutamol or ipratropium using different criteria in treatment-naïve patients with asthma and COPD

European Clinical Respiratory Journal
Background The criteria for significant bronchodilator responsiveness (BDR) were published in 2005 by the European Respiratory Society/American Thoracic Society, which were revised in 2021, however, data on the agreement between these two recommendations
Zsófia Lázár, Alpár Horváth, Szilvia Kiss-Dala, Zsolt Abonyi-Tóth, Balázs Csoma, Katalin Kontz, Lilla Tamási, Veronika Müller   +7 more
doaj   +1 more source