Results 111 to 120 of about 20,702 (286)

A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients

International Journal of COPD, 2020
José Luis López-Campos,1,2 Bernardino Alcázar Navarrete,3 Juan Antonio Riesco Miranda,2,4 Borja G Cosío,2,5 Juan P de-Torres,6 Bartolomé Celli,7 Carlos A Jiménez-Ruiz,8 Ciro Casanova Macario9 1Unidad Mé ...
López-Campos JL, Alcázar Navarrete B, Riesco Miranda JA, Cosío BG, de-Torres JP, Celli B, Jiménez-Ruiz CA, Casanova Macario C   +7 more
doaj  

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C., Lim, J.N.W., Peters, J., Smith, S., Stevenson, M.   +4 more
core   +1 more source

Medication adherence during the run‐in phase of clinical trials: A systematic review of methodological and reporting rigour

British Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3353-3365, December 2025.
Aims Trial run‐in phases are sometimes used to select adherent participants as a strategy to enrich trials, but the methods employed lack clear regulatory guidance and there are concerns about the transparency of reporting. This review aims to characterize the methods used for adherence measurement and public reporting of run‐in studies.
Non Davies, Bernard Vrijens, Daniel F. B. Wright, Dyfrig A. Hughes   +3 more
wiley   +1 more source

Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD

Pulmonary Therapy, 2019
Inhaled fixed-dose combinations (FDCs) of a long-acting β-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD patients.
Anthony D’Urzo, Kenneth R. Chapman, James F. Donohue, Peter Kardos, M. Reza Maleki-Yazdi, David Price   +5 more
doaj   +1 more source

[Tiotropium, a long-acting bronchodilating agent for the treatment of COPD]. [PDF]

Nederlands tijdschrift voor geneeskunde, 2006
The goals of COPD management according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline are: prevention of disease progression, relief of symptoms, improvement of exercise tolerance and the quality of life, prevention and treatment of exacerbations and complications, and reduction of mortality and adverse effects.
Schuurbiers, O.C.J., Schermer, T.R.J., Dekhuijzen, P.N.R., Weel, C. van   +3 more
openaire   +2 more sources

Tracheal relaxing effects and β₂ adrenoceptor selectivity of S1319, a novel sponge‐derived bronchodilator agent, in isolated guinea‐pig tissues [PDF]

, 1999
Hidefumi Suzuki, Akihiro Ueno, Masao Takei, Kazutoshi Sindo, Toru Miura, Masayuki Sakakibara, Tatsuo Higa, Hiromi Fukamachi   +7 more
openalex   +1 more source

Effect of carbocisteine in prevention of exacerbation of chronic obstructive pulmonary disease (CAPRI study): an observational study [PDF]

, 2016
Chronic Obstructive Pulmonary Disease (COPD) is a chronic and progressive lung disease characterized by irreversible airflow obstruction, airway inflammation , oxidative stress and, often, mucus hypersecretion.
BOCCHINO, MARIALUISA, BRUZZESE, DARIO, Esposito, Antonietta, PONTICIELLO, ANTONIO, SANDUZZI ZAMPARELLI, ALESSANDRO, STANZIOLA, ANNA AGNESE, Valentino, Maria Rosaria   +6 more
core   +1 more source

A Rare and Severe Multisystem Cascade of AKI, ARDS, and Septic Shock Leading to Acalculous Cholecystitis in a Young Scrub Typhus Patient: A Case Report From Nepal

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushi, is an acute febrile illness prevalent in Nepal with a wide spectrum of clinical presentations. Severe forms can lead to multiorgan dysfunction, including acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), septic shock, and rarely, acalculous cholecystitis.
Prabhat Kaphle, Maya Upadhyaya, Sarjan Shrestha, Amrita Shrestha, Dhanlaxmi Giri, Kamal Hamal, Liladhar Ojha   +6 more
wiley   +1 more source

Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology

Allergology International, 2002
The mainstay of chronic asthma management consists of using pharmacological agents that induce bronchodilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), and that control the chronic inflammatory process, such ...
Kian Fan Chung
doaj   +1 more source

Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study [PDF]

, 2019
The role of the beta(2)-adrenergic receptor (ADRB2) gene in patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated the association between ADRB2 variants and the risk of exacerbations in COPD patients treated with inhaled ...
Brusselle, Guy, Ghanbari, Mohsen, Karimi, Leila, Lahousse, Lies, Stricker, Bruno H., Terzikhan, Natalie, Uitterlinden, Andre G., van der Lei, Johan, Verhamme, Katia   +8 more
core   +2 more sources