Results 91 to 100 of about 1,517,186 (231)
A Rare Case of COPA Syndrome: Multisystem Relapse and Fatal Septic Complication
Respirology Case Reports, Volume 14, Issue 9, September 2026.A 45‐year‐old man with a history of recurrent respiratory failure, arthritis and renal dysfunction was diagnosed with COPA syndrome through genetic testing after years of progressive interstitial lung disease and immune‐mediated manifestations. He initially responded to immunosuppressive therapy but relapsed after treatment discontinuation, developing ...
Flavia Castro Velasco Fernandes +7 more
wiley +1 more source
Respiratory Research, 2019 Background This cohort study of patients with chronic obstructive pulmonary disease (COPD) was performed to evaluate the status of inhaled corticosteroid (ICS) prescriptions following the 2017 revision of the Global Initiative for Chronic Obstructive ...
Se Hee Lee +9 more
doaj +1 more source
Allergy, Volume 81, Issue 9, Page 3221-3235, September 2026.This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake +8 more
wiley +1 more source
, 2015 Roberta Pisi,1 Marina Aiello,1 Andrea Zanini,2 Panagiota Tzani,1 Davide Paleari,3 Emilio Marangio,1 Antonio Spanevello,2,4 Gabriele Nicolini,5 Alfredo Chetta1 1Department of Clinical and Experimental Medicine, University of Parma, Parma, 2Division of ...
Pisi R +8 more
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A positive bronchodilator response has been defined as a 12% increase in the forced expiratory volume in one second (FEV ) or forced vital capacity (FVC) from their respective pre-bronchodilator values, combined with at least a 0.2 L absolute change ...
Grealis, Kyle +3 more
core +1 more source
Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma
Respiratory Research, 2017 Background Small non-coding RNAs (microRNAs) have been evolved to master numerous cellular processes. Genetic variants within microRNA seed region might influence microRNA biogenesis and function.
Eman A. Toraih +6 more
doaj +1 more source
Allergy, Volume 81, Issue 9, Page 3345-3360, September 2026.Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
Impact of bronchodilator therapy on exercise tolerance in COPD
, 2010 B AguilaniuHYLAB, Laboratory of Clinical Physiology and Exercise, Grenoble, FranceAbstract: Exercise tolerance is an important parameter in patients with COPD and a primary goal of treatment is to reduce dyspnea to facilitate physical activities and ...
B Aguilaniu
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Adaptive Expressiveness – Virtual Conversational Agents That Can Align to Their Interaction Partner [PDF]
, 2010 Buschmeier H, Bergmann K, Kopp S. Adaptive Expressiveness – Virtual Conversational Agents That Can Align to Their Interaction Partner. In: van der Hoek W, Kaminka GA, Luck M, Sen S, eds.
Kopp, Stefan ; https://orcid.org/ +6 more
core
, 2003 Chronic obstructive pulmonary disease (COPD) is a common, complex disease associated with significant and increasing morbidity and mortality. The cardinal feature of COPD is persistent airflow obstruction, measured by reductions in quantitative ...
Celedon, JC +5 more
core +1 more source