Results 81 to 90 of about 13,974 (221)

Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma

Respiratory Research, 2017
Background Small non-coding RNAs (microRNAs) have been evolved to master numerous cellular processes. Genetic variants within microRNA seed region might influence microRNA biogenesis and function.
Eman A. Toraih, Mohammad H. Hussein, Essam Al Ageeli, Eman Riad, Nouran B. AbdAllah, Ghada M. Helal, Manal S. Fawzy   +6 more
doaj   +1 more source

ANTICHOLINERGIC THERAPY IN CYSTIC-FIBROSIS PATIENTS [PDF]

, 1995
A significant proportion of patients with cystic fibrosis (CF) demonstrate increased airways hyperreactivity, a feature that has been well documented by several authors.
Sánchez Díaz, Ignacio, Sanchez I.
core   +1 more source

Classification of Patients with COPD on LAMA Monotherapy Using the GOLD Criteria: Analysis of a Claims-Linked Patient Survey Study

Pulmonary Therapy, 2019
Introduction To address the burden of chronic obstructive pulmonary disease (COPD), the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends treatment according to classification of patients by symptom severity and exacerbation risk ...
Riju Ray, Beth Hahn, Richard H. Stanford, John White, Breanna Essoi, Alyssa Goolsby Hunter   +5 more
doaj   +1 more source

Current Evidence on the Usefulness of Potential Therapies in the Prevention of COPD Exacerbations: Beyond the Use of Bronchodilator Therapy and Inhaled Corticosteroids [PDF]

Prevention of exacerbations is a key objective in chronic obstructive pulmonary disease (COPD) management. The adverse effects of an exacerbation include a negative impact on patient quality of life and symptoms, an accelerated rate of decline in lung ...
Hurtado-Fuentes, Álvaro, Callejas-González, Francisco Javier, Miguel-Díez, Javier de, Golpe, Rafael, Marín-Oto, Marta, Loscertales-Vacas, Guillermo Samuel, Máiz-Carro, Luis, Figueira-Gonçalves, Juan Marco, Tordera-Mora, José María   +8 more
core   +1 more source

Farming environments and childhood atopy, wheeze, lung function, and exhaled nitric oxide [PDF]

, 2012
BACKGROUND: Previous studies have demonstrated that children raised on farms are protected from asthma and allergies. It is unknown whether the farming effect is solely mediated by atopy or also affects nonatopic wheeze phenotypes.
Sozanska, Barbara, Sozanska, B., Heederik, D., Braun-Fahrländer, C., Latzin, Philipp, Frey, Urs, Dep IRAS, Heederik, Dick, Risk Assessment of Toxic and Immunomodulatory Agents, Büchele, Gisela, Weber, J., GABRIELA Study Group,, Latzin, P., von Mutius, E., Fuchs, O., von Mutius, Erika, Fuchs, Oliver, Frey, U., Loss, Georg, Boznanski, A., Loss, G., Horak, Elisabeth, Genuneit, J., Genuneit, Jon, Horak, E., Braun-Fahrländer, Charlotte, Weber, Juliane, Buchele, G., Boznanski, Andrzej   +28 more
core   +1 more source

Influence of ADRB2 variants on bronchodilator response and asthma control in a mixed population [PDF]

Jornal Brasileiro de Pneumologia
Objective: Given that b2 agonists constitute the primary treatment for asthma and that treatment response varies as a result of polymorphisms in the ADRB2 gene, we sought to investigate the associations between ADRB2 gene variants and bronchodilator ...
Pedro Augusto Silva dos Santos Rodrigues, Álvaro Augusto Souza da Cruz Filho, Helena Mariana Pitangueira Teixeira, Luciano Gama da Silva Gomes, Hatilla dos Santos Silva, Juliana Lopes Rodrigues, Almirane Lima de Oliveira, Cinthia Vila Nova Santana, Gabriela Pimentel Pinheiro das Chagas, Camila Alexandrina Viana de Figueiredo, Ryan dos Santos Costa   +10 more
doaj   +1 more source

[Tiotropium, a long-acting bronchodilating agent for the treatment of COPD]. [PDF]

Nederlands tijdschrift voor geneeskunde, 2006
The goals of COPD management according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline are: prevention of disease progression, relief of symptoms, improvement of exercise tolerance and the quality of life, prevention and treatment of exacerbations and complications, and reduction of mortality and adverse effects.
Schuurbiers, O.C.J., Schermer, T.R.J., Dekhuijzen, P.N.R., Weel, C. van   +3 more
openaire   +2 more sources

Bronchodilator therapy for chronic cough [PDF]

, 2017
Experimental studies indicate that airway calibre increases the sensitivity of the afferents involved in the cough reflex but it has proved difficult to demonstrate that airway calibre increases the sensitivity of the afferents involved in the cough ...
Paola Rogliani, Cazzola, Mario, Mario Cazzola, Matera, Mg, Rogliani, P, Zanasi, A, MATERA, Maria Gabriella, Cazzola, M, Rogliani, Paola, Alessandro Zanasi, Zanasi, Alessandro, Maria Gabriella Matera   +11 more
core   +1 more source

A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients

International Journal of COPD, 2020
José Luis López-Campos,1,2 Bernardino Alcázar Navarrete,3 Juan Antonio Riesco Miranda,2,4 Borja G Cosío,2,5 Juan P de-Torres,6 Bartolomé Celli,7 Carlos A Jiménez-Ruiz,8 Ciro Casanova Macario9 1Unidad Mé ...
López-Campos JL, Alcázar Navarrete B, Riesco Miranda JA, Cosío BG, de-Torres JP, Celli B, Jiménez-Ruiz CA, Casanova Macario C   +7 more
doaj  

Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD

Pulmonary Therapy, 2019
Inhaled fixed-dose combinations (FDCs) of a long-acting β-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD patients.
Anthony D’Urzo, Kenneth R. Chapman, James F. Donohue, Peter Kardos, M. Reza Maleki-Yazdi, David Price   +5 more
doaj   +1 more source