Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
Bronchodilator response assessment through impulse oscillometry system and spirometry in children and adolescents with cystic fibrosis [PDF]
Objective: To investigate the effect of bronchodilator on the respiratory mechanics and pulmonary function of children and adolescents with cystic fibrosis.
Tayná Castilho +5 more
doaj +1 more source
Improvements With Tiotropium Maintenance Therapy in COPD Patients Without Dyspnea
In a post hoc analysis of the Tie‐COPD trial, including 305 patients with mild‐to‐moderate COPD and no dyspnea (mMRC 0), 2 years of tiotropium improved lung function, lowered the annual exacerbation rate, and delayed the first clinically important deterioration, indicating benefit beyond symptom relief in a group not currently offered maintenance ...
Zihui Wang +15 more
wiley +1 more source
Bronchodilator responsiveness and reported respiratory symptoms in an adult population. [PDF]
The relationship between patient-reported symptoms and objective measures of lung function is poorly understood.To determine the association between responsiveness to bronchodilator and respiratory symptoms in random population samples.4669 people aged ...
A. Sonia Buist (390258) +24 more
core +1 more source
Objective: To compare a once-daily long-acting β2 agonist (indacaterol 150 µg) with a once-daily long-acting anticholinergic (tiotropium 5 µg) in terms of their effects on exercise endurance (limit of tolerance, Tlim) in patients with moderate COPD ...
Danilo Cortozi Berton +5 more
doaj +1 more source
Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion +11 more
wiley +1 more source
Daphne C Richter1, James R Joubert1, Haylene Nell1, Mace M Schuurmans2, Elvis M Irusen21Tiervlei Trial Centre, Karl Bremer Hospital, Bellville, RSA; 2Respiratory Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of ...
Elvis M Irusen +4 more
core
Bronchodilator reversibility in patients with asthma and persistent airflow limitation
Bronchodilator reversibility could be explored in the ATLANTIS cohort to better understand the association between PAL and bronchodilator reversibility in the context of this new phenotype of patients with ...
Patruno, Vincenzo +3 more
core +1 more source
Phenotypic Clusters of Severe Asthma and Response to Dupilumab in Real‐World Practice
ABSTRACT Background Severe asthma is a heterogeneous disease with variable clinical and inflammatory profiles that may influence responses to biological therapies. Identifying phenotypic clusters may help optimize patient selection and treatment outcomes.
Daria S. Fomina +9 more
wiley +1 more source
Determinants of invasive ventilation in infants with acute bronchiolitis: an observational study of pre-hospital and in-hospital treatments [PDF]
Objective: To analyze the factors associated with invasive ventilation in infants admitted to the hospital with acute bronchiolitis and identify the treatments administered before and during hospitalization.
Carlos Henrique Araújo Carvalho +3 more
doaj +1 more source

