Results 91 to 100 of about 343,394 (253)
A Universal Protein Ladder for Standardization of Diverse FRET Assays
Advanced Science, EarlyView.Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith +5 more
wiley +1 more source
Broth dilution and agar dilution methods applied to Candida sensitivity tests
, 1992 Os autores compararam o desempenho das técnicas de diluição em caldo e diluição em ágar, mediante a determinação da CIM (concentração inibitória mínima) e da CFM (concentração fungicida mínima) de antifúngicos poliênicos e imidazólicos, frente a diversas
Alves, Sydney Hartz, Cury, Ariete Emily
core
Quantification of growth hormone in serum by isotope dilution mass spectrometry [PDF]
, 2009 Inter-assay variation of antibody based routine tests is hampering comparability of measurement results for growth hormone (GH) between different laboratories and decision making in clinical practice. Here it is demonstrated, that quantification of GH by
André Henrion +4 more
core
Advanced Science, EarlyView.High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld +5 more
wiley +1 more source
Advanced Science, EarlyView.This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang +11 more
wiley +1 more source
Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]
, 2011 In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh +11 more
core +1 more source
Advanced Science, EarlyView.A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang +12 more
wiley +1 more source
Hoboken - The Famous Clam Broth House Sign
, 2007 The Clam Broth House (1899 2004), was a landmark Hoboken restaurant that operated for over a century. The Clam Broth House opened in 1899. which used several giant hand-shaped signs to advertise .
Beards, Daniel E.
core
Minimum Inhibitory concentrations of 108 Carbapenem-resistant gram negative bacteria were listed.MIC obtained from Micro broth dilution, Agar dilution and Colistin broth disc elution were added.The interpretive category of each MIC is also included.THIS ...
Padmini Radhakrishnan, S (via Mendeley Data) +1 more
core +1 more source
Advanced Science, EarlyView.Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang +20 more
wiley +1 more source