Results 131 to 140 of about 1,141,798 (294)

Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood [PDF]

open access: yes, 2008
Epidemiological studies comparing typical Western and traditional Eastern lifestyles indicate that dietary intake of soyderived phytoestrogens, including genistein, daidzein, and equol, may have significant health protective effects on hormone-dependent ...
Bracke, Marc   +4 more
core  

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]

open access: yes, 2001
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH   +7 more
core   +3 more sources

Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization

open access: yesNature Communications, 2019
β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles of the transcription factor Foxp1 in brown/beige adipocyte differentiation and thermogenesis ...
Pei Liu   +16 more
semanticscholar   +1 more source

TSH effects on thermogenesis in rat brown adipocytes

open access: yesMolecular and Cellular Endocrinology, 2015
TSH receptor (TSHR) is present in the thyroid and other tissues, as adipose tissue. In brown adipose tissue (BAT) TSH increases UCP1 expression and lipolysis. We have studied the regulation of Tshr mRNA expression and the effect of TSH on Ucp1 and Dio2 mRNA, on D2 activity and O2 consumption in rat brown adipocytes and the TSH signaling pathways.
Martínez de Mena, Raquel   +3 more
openaire   +5 more sources

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. [PDF]

open access: yes, 2016
Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress.
Behan, James W   +6 more
core   +1 more source

The complex interactions between obesity, metabolism and the brain [PDF]

open access: yes, 2019
Obesity is increasing at unprecedented levels globally, and the overall impact ofobesity on the various organ systems of the body is only beginning to be fullyappreciated. Because of the myriad of direct and indirect effects of obesity causingdysfunction
Keller, Jeffrey Neil   +1 more
core   +1 more source

Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity

open access: yesBMC Complementary and Alternative Medicine, 2019
Background Brown adipocytes are known to promote energy expenditure and limit weight gain to combat obesity. Averrhoa bilimbi, locally called belimbing buluh (DBB), is mainly used as an ethnomedicine in the treatment of metabolic disorders including ...
Wai Kwan Lau   +7 more
doaj   +1 more source

Deletion of SIRT1 in perivascular adipose tissue accelerates obesity-induced endothelial dysfunction [PDF]

open access: yes, 2015
Conference Theme: Tomorrow’s medicines: pharmacology, patients and populationsINTRODUCTION: Perivascular adipose tissue (PVAT) exhibits brown adipose features and its dysfunction is implicated in cardiovascular diseases.
Gu, P   +4 more
core  

Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages

open access: yesMediators of Inflammation, 2019
Obesity is a metabolic condition associated with multiple health problems such as endocrine and metabolic dysfunction and chronic inflammation in adipose tissues.
Wen-Chao Zhang   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy