Results 291 to 300 of about 1,154,949 (367)

NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis. [PDF]

Mol Metab
Zhou WY, Liu P, Xia YF, Shi YJ, Xu HY, Ding M, Yang QQ, Qian SW, Tang Y, Lu Y, Tang QQ, Liu Y.   +11 more
europepmc   +1 more source

Sex‐Specific Subcutaneous Adipose Tissue Transcriptome in Obesity: Insights From Monozygotic Twin Pairs Discordant for BMI

Obesity, Volume 34, Issue 2, Page 394-406, February 2026.
ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia, Maheswary Muniandy, Sini Heinonen, Sina Saari, Marcus Alvarez, Antti Hakkarainen, Jesper Lundbom, Juho Kuula, Per‐Henrik Groop, Jaakko Kaprio, Päivi Pajukanta, Kirsi H. Pietiläinen, Birgitta W. van der Kolk   +12 more
wiley   +1 more source

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice. [PDF]

Dev Cell
Shi Z, Xiong S, Hu R, Wang Z, Park J, Qian Y, Wang J, Bhalla P, Velupally N, Song Q, Song Z, Jeon MS, Zhang KK, Xie L, Layden BT, Ong SG, Jiang Y.   +16 more
europepmc   +1 more source

Acyl‐CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark, R. Petersen, P. M. M. Ruppert, E. S. Jul, T. K. Doktor, R. Nielsen, J. F. Kappel, S. Larsen, J. W. Kornfeld, S. Mandrup, B. S. Andresen, J. Havelund, D. Neess, N. J. Færgeman   +13 more
wiley   +1 more source

A comparative assessment of reference genes in mouse brown adipocyte differentiation and thermogenesis in vitro. [PDF]

Adipocyte
Lai TH, Hwang JS, Ngo QN, Lee DK, Kim HJ, Kim DR.   +5 more
europepmc   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

Equisetin inhibits adiposity through AMPK-dependent regulation of brown adipocyte differentiation. [PDF]

Heliyon
Zhong Q, Wang X, Wei R, Liu F, Alamin M, Sun J, Gui L.   +6 more
europepmc   +1 more source

CD90 Is Dispensable for White and Beige/Brown Adipocyte Differentiation. [PDF]

Int J Mol Sci, 2020
Dahlhaus M, Roos J, Engel D, Tews D, Halbgebauer D, Funcke JB, Kiener S, Schuler PJ, Döscher J, Hoffmann TK, Zinngrebe J, Rojewski M, Schrezenmeier H, Debatin KM, Wabitsch M, Fischer-Posovszky P.   +15 more
europepmc   +1 more source

Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring

Journal of Physiology, 2017
T. Zou, Daiwen Chen, Qiyuan Yang, Bo Wang, Mei-Jun Zhu, P. Nathanielsz, M. Du   +6 more
semanticscholar   +1 more source

Gpx4 Deletion‐Mediated Macrophage Ferroptosis Alleviates Obesity‐Associated Insulin Resistance

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Macrophage‐specific loss of Gpx4 induces ferroptosis, thereby alleviating high‐fat diet (HFD)‐induced obesity, insulin resistance, and metabolic dysfunction, and conferring systemic metabolic protection in type 2 diabetes (T2D). ABSTRACT Obesity has become a global epidemic and a major contributor to the development of Type 2 diabetes (T2D) through the
Suhua Wu, Juan Peng, Xiaodong Wang, Hong Gao, Huangrui Fang, Shiyi Hu, Qiufen Wei, Yuanye Dang, Haixia Tu, Mingyan Zhu, Jianye Peng, Yumiao Liu, Gaofeng Zeng, Xiaoyan Dai   +13 more
wiley   +1 more source