The β-adrenergic receptor-SGK1 signaling pathway in brown adipocytes protects GOT1 from proteasomal degradation [PDF]
Chul‐Hong Park +3 more
openalex +1 more source
Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian +5 more
wiley +1 more source
The role of dicer in brown adipocyte differentiationin vivo
Jessica Lais de Oliveira [UNIFESP] Branquinho
openalex +1 more source
Ultrastructural alterations of rat brown adipocytes after short-term corticosterone treatment
Maja Cakic-Milosevic +3 more
openalex +2 more sources
Biochemical and Physiological Effects of Galanin in Health and Disease
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function. [PDF]
Huang M +7 more
europepmc +1 more source
Enhanced cancerous properties of breast cancer cell and brown adipocyte co-cultures compared to their fused cells [PDF]
Shangying Hu +5 more
openalex +1 more source
TNF/TNFR1 is a Key Regulator of Prolonged Fasting‐Induced Decrease in Adipose Tissue
Fasting triggers an inflammatory response and increases sympathetic tone in white adipose tissue (WAT), promoting fat breakdown and tissue remodeling. Fasting sparks an inflammatory response that underpins the reduction in adipocyte size and WAT remodeling.
Amanda Carla Clemente de Oliveira +12 more
wiley +1 more source
A Somatic Mutation in HIF‐2α Affects Glucose and Lipid Metabolism via CD36 and Ceramide
A mutation within the C‐terminal transactivation domain of HIF‐2α enhances Cd36 expression by increased transactivation activity, leading to ceramide accumulation and disruption of glucose and lipid metabolism. Inhibition of ceramide synthesis by myriocin reduces ceramide levels and ameliorates these metabolic disturbances.
Feiqiong Gao +9 more
wiley +1 more source

