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White adipocytes transdifferentiation into brown adipocytes induced by triiodothyronine

2008
The uncontrolled expansion of white adipose tissue (WAT) seen in obesity predisposes affected individuals to health complications. Another type of fat, brown adipose tissue (BAT) has an opposing physiological function because it allows dissipation instead of storage of energy.
A. Korac   +9 more
openaire   +1 more source

Proteomic differences between white and brown adipocytes

Amino Acids, 2014
Although a series of protein levels from several protein pathways have been shown to differ between white (WA) and brown (BA) adipocytes, proteomic work on this subject with the exception of mitochondrial protein differences is limited. It was, therefore, the aim of the study to compare WA with BA soluble protein levels. Proteins were extracted from WA
Wei-Qiang, Chen, Lin, Li, Gert, Lubec
openaire   +2 more sources

AcroBATics: how dying brown adipocytes trigger browning

Nature Reviews Endocrinology, 2022
Julia Zinngrebe   +1 more
openaire   +2 more sources

Trans-anethole ameliorates obesity via induction of browning in white adipocytes and activation of brown adipocytes

Biochimie, 2018
To treat obesity, suppression of white adipose tissue (WAT) expansion and activation of brown adipose tissue (BAT) are considered as potential therapeutic targets. Recent advances have been made in the induction of brown fat-like adipocytes (beige) in WAT, which represents an attractive potential strategy for the management and treatment of obesity ...
Nam Hyeon, Kang   +4 more
openaire   +2 more sources

Branching out beyond canonical brown adipocyte function

Cell Metabolism
Brown adipose tissue has long been functionally characterized as an organ that regulates thermogenesis, body weight set point, and glucose homeostasis. In the May 9, 2024, issue of Cell, Verkerke et al. discover a novel function for brown adipose tissue in processing branched-chain amino acids into antioxidant metabolites that enter the circulation and
Helaina, Von Bank, Judith, Simcox
openaire   +2 more sources

Functional differentiation of white and brown adipocytes

BioEssays, 1997
AbstractAdipose tissue plays an important role in mammalian energy equilibrium not only as a lipid‐dissipating, i.e. energy‐storing, tissue (white adipose tissue), but also as an energy‐dissipating one (brown adipose tissue). Brown adipocytes have the ability of facultative heat production due to a unique mitochondrial protein, the uncoupling protein ...
openaire   +2 more sources

The brown adipocyte: What a story!

Annales d'Endocrinologie
D. Ricquier
semanticscholar   +1 more source

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