Results 61 to 70 of about 1,141,798 (294)
International Journal of Molecular Sciences, 2019 The high abundance of mitochondria and the expression of mitochondrial uncoupling protein 1 (UCP1) confer upon brown adipose tissue (BAT) the unique capacity to convert chemical energy into heat at the expense of ATP synthesis.
Donghwan Kim +6 more
semanticscholar +1 more source
The Mechanism of White and Brown Adipocyte Differentiation [PDF]
Diabetes & Metabolism Journal, 2013 Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity worldwide. The pathogenesis and pathophysiology of metabolic syndrome can well be understood by studying the molecular mechanisms that control the development and function of adipose tissue.
openaire +4 more sources
Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]
, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana +2 more
core +4 more sources
CREG1 stimulates brown adipocyte formation and ameliorates diet‐induced obesity in mice
The FASEB Journal, 2019 Increased formation of brown and beige adipocytes is critical for adaptive thermogenesis to maintain homeothermy in cold or to circumvent diet‐induced obesity (DIO). Cellular repressor of adenovirus early region 1A‐stimulated genes 1 (CREG1) exhibits the
M. Hashimoto +5 more
semanticscholar +1 more source
PPARγ in the control of brown adipocyte differentiation
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2005 The effects of fatty acids and retinoic acid (carotene) on brown adipose tissue differentiation are mediated by activation of the transcription factors PPARgamma and PPARalpha in combination with RXR. There is good support for the idea that activated PPARgamma promotes adipogenesis also in brown adipose tissue.
Natasa Petrovic +4 more
openaire +3 more sources
Brown Adipogenic Reprogramming Induced by a Small Molecule
Cell Reports, 2017 Brown adipose tissue (BAT) has attracted considerable research interest because of its therapeutic potential to treat obesity and associated metabolic diseases.
Baoming Nie +15 more
doaj +1 more source
Modulation of intestinal microbiota and immunometabolic parameters by caloric restriction and lactic acid bacteria [PDF]
, 2018 The objective of this work was to evaluate the effect of a caloric restriction diet with and without the administration of Lactobacillus fermentum CRL1446, Lactobacillus casei CRL431 and Lactococcus lactis CRL1434, on immunemetabolic parameters and the ...
Abeijon Mukdsi, Maria Claudia +5 more
core +1 more source
Brown adipocyte glucose metabolism: a heated subject
EMBO Reports, 2018 The energy expending and glucose sink properties of brown adipose tissue (BAT) make it an attractive target for new obesity and diabetes treatments. Despite decades of research, only recently have mechanistic studies started to provide a more complete ...
M. Hankir, M. Klingenspor
semanticscholar +1 more source
Effects of exercise on brown and beige adipocytes
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise.
Kristin I. Stanford, Revati S. Dewal
openaire +3 more sources
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression. [PDF]
PLoS Genetics, 2017 Given the relevance of beige adipocytes in adult humans, a better understanding of the molecular circuits involved in beige adipocyte biogenesis has provided new insight into human brown adipocyte biology. Genetic mutations in SLC39A13/ZIP13, a member of
Ayako Fukunaka +17 more
doaj +1 more source