Results 91 to 100 of about 68,398 (313)

Enzymes concerned in the synthesis of glycogen from glucose in the brown adipose tissue [PDF]

, 1951
N. H. Creasey, C. H. GRAY
openalex   +1 more source

NRF2‐REGγ‐ACADM/KLF15 Signaling Pathway Regulates the Browning of White Adipose Tissue to Modulate Obesity

Advanced Science, EarlyView.
This study identifies that REGγ is elevated in obese adipose tissue. REGγ modulates WAT browning via ubiquitin‐independent ACADM/KLF15–UCP1 degradation. Overactivation of the NRF2–REGγ axis facilitates adipose tissue function to cause obesity. Inhibition of REGγ in the iWAT alleviates HFD‐induced obesity.
Hui Chen, Qiujing Guan, Shuangming Gong, Yingying Du, Zhidan Zhang, Yan Liu, Lei Zhou, Lin Liu, Baoquan Xin, Yilan Guo, Hui Zhang, Ziyang Zhou, Tongchao Pei, Guohong Yu, Sokun Yin, Lei Li   +15 more
wiley   +1 more source

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

Advanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye, Xinyi Wu, Jin Liu, Yongmi Guo, Chong Ji, Zhouyue Wang, Di Yang, Min Zhou   +7 more
wiley   +1 more source

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

Cell Reports, 2013
The phenomenon of white fat “browning,” in which certain white adipose tissue depots significantly increase gene expression for the uncoupling protein UCP1 and thus supposedly acquire thermogenic, fat-burning properties, has attracted considerable ...
Irina G. Shabalina, Natasa Petrovic, Jasper M.A. de Jong, Anastasia V. Kalinovich, Barbara Cannon, Jan Nedergaard   +5 more
doaj   +1 more source

Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity

Advanced Science, EarlyView.
In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie, Runzhi Huang, Weijin Qian, Xinran Ding, Wei Zhang, Yixu Li, Jianyu Lu, Hanlin Sun, Yifan Liu, Yuntao Yao, Bingnan Lu, Minjuan Wu, Zhaofan Xia, Shizhao Ji   +13 more
wiley   +1 more source

Calcium accumulation as a parameter of energy metabolism in mitochondria of brown adipose tissue. [PDF]

, 1967
K.J. Hittelman, A.S. Fairhurst, Robert E. Smith   +2 more
openalex   +1 more source

Irisin‐Loaded Dissolving Microneedles Promote Rapid Wound Healing

Advanced NanoBiomed Research, EarlyView.
Schematic of effective wound healing facilitated by water‐degradable microneedles loaded with irisin that enhance irisin penetration, fibroblast migration, differentiation, and extracellular matrix synthesis at the wound site. Irisin, an exercise‐induced myokine with anti‐inflammatory and regenerative activity, is incorporated into dissolving poly ...
Yu‐Chi Pan, Sheng‐Hua Wu, Hung‐Pei Tsai, Ming‐Hong Tai, Chien‐Ju Lin, Hung‐Wei Yang, Shu‐Hung Huang   +6 more
wiley   +1 more source

mmunohistochemical Identification And Quantification Of Brown Adipocytes In Human Adipose Tissue.

مجله كليه طب الكندي, 2016
Background: Obesity is a worldwide challenge and is closely connected to many metabolic diseases. Two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT) have been identified.
Insaf Jasim Mahmoud, Insaf Jasim Mahmoud, bdul Hadi Liebi, Faris Abdul Kareem Khazaal   +3 more
doaj  

White-to-Beige and Back: Adipocyte Conversion and Transcriptional Reprogramming

Pharmaceuticals
Obesity has become a pandemic, as currently more than half a billion people worldwide are obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary and behavioral factors, such as nutritional inadequacy, along with the ...
Stanislav Boychenko, Vera S. Egorova, Andrew Brovin, Alexander D. Egorov   +3 more
doaj   +1 more source

Oxidative Metabolism in Cells Isolated from Brown Adipose Tissue [PDF]

, 1968
Stanley B. Prusiner, Barbara Cannon, Te May Ching, Olle R. Lindberg   +3 more
openalex   +1 more source