Results 101 to 110 of about 89,596 (339)

Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression.

PLoS ONE, 2015
Brown fat generates heat to protect against cold and obesity. Adrenergic stimulation activates the thermogenic program of brown adipocytes. Although the bioactivity of brown adipose tissue in adult humans had been assumed to very low, several studies ...
Gaku Nagano, Haruya Ohno, Kenji Oki, Kazuhiro Kobuke, Tsuguka Shiwa, Masayasu Yoneda, Nobuoki Kohno   +6 more
doaj   +1 more source

[18F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue

Communications Biology
Brown and brown-like adipose tissues have attracted significant attention for their role in metabolism and therapeutic potential in diabetes and obesity.
Jelena Levi, Caroline Guglielmetti, Timothy J. Henrich, John C. Yoon, Prafulla C. Gokhale, David A. Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J. Peluso, Tony L. Huynh, Sung-Min An, Mark Dornan, Anthony P. Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M. Chaumeil, Henry F. VanBrocklin, Hee-Don Chae   +21 more
doaj   +1 more source

Brown adipose tissue thermogenesis in humans [PDF]

Diabetologia, 2013
The prevalence of obesity and type 2 diabetes is at epidemic proportions. Classical interventions aimed at targeting obesity, such as reducing energy intake or increasing exercise, are often not effective over the long term. In contrast to white adipocytes, which store energy, brown adipocytes generate heat via mitochondrial uncoupling protein 1 ...
openaire   +3 more sources

Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency

EBioMedicine, 2019
Background: Inflammation is the most relevant mechanism linking obesity with insulin-resistance and metabolic disease. It impacts the structure and function of tissues and organs involved in metabolism, such as the liver, pancreatic islets and the ...
José C. de-Lima-Júnior, Gabriela F. Souza, Alexandre Moura-Assis, Rodrigo S. Gaspar, Joana M. Gaspar, Andréa L. Rocha, Danilo L. Ferrucci, Tanes I. Lima, Sheila C. Victório, Ivan L.P. Bonfante, Claudia R. Cavaglieri, José C. Pareja, Sérgio Q. Brunetto, Celso D. Ramos, Bruno Geloneze, Marcelo A. Mori, Leonardo R. Silveira, Gesmar R.S. Segundo, Eduardo R. Ropelle, Lício A. Velloso   +19 more
doaj  

Electron Density of Adipose Tissues Determined by Phase-Contrast Computed Tomography Provides a Measure for Mitochondrial Density and Fat Content

Frontiers in Physiology, 2018
Phase-contrast computed tomography (PCCT) is an X-ray-based imaging method measuring differences in the refractive index during tissue passage. While conventional X-ray techniques rely on the absorption of radiation due to differing tissue-specific ...
Lorenz Birnbacher, Stefanie Maurer, Stefanie Maurer, Katharina Scheidt, Julia Herzen, Franz Pfeiffer, Franz Pfeiffer, Franz Pfeiffer, Tobias Fromme, Tobias Fromme   +9 more
doaj   +1 more source

Simple mechanical cues could explain adipose tissue morphology [PDF]

arXiv, 2017
The mechanisms by which organs acquire their functional structure and realize its maintenance (or homeostasis) over time are still largely unknown. In this paper, we investigate this question on adipose tissue. Adipose tissue can represent 20 to 50% of the body weight.
arxiv  

Brown Adipose Tissue in Cetacean Blubber

PLOS ONE, 2015
Brown adipose tissue (BAT) plays an important role in thermoregulation in species living in cold environments, given heat can be generated from its chemical energy reserves. Here we investigate the existence of BAT in blubber in four species of delphinoid cetacean, the Pacific white-sided and bottlenose dolphins, Lagenorhynchus obliquidens and Tursiops
Satoru Doi, Hirofumi Ohtsuki, Junji Shindo, Masayuki Funaba, Hideki Endo, Kento Amou, Sara Kobayashi, Osamu Hashimoto, Ryo Sato, Ayaka Matsuda, Takehiko Kakizaki, Fumio Terasawa, Takashi Matsuishi, Makoto Sugiyama   +13 more
openaire   +5 more sources

Evaluation of physiological stress in free‐ranging bears: current knowledge and future directions

Biological Reviews, Volume 98, Issue 1, Page 168-190, February 2023., 2023
ABSTRACT Stress responses, which are mediated by the neurogenic system (NS) and hypothalamic–pituitary–adrenal (HPA) axis help vertebrates maintain physiological homeostasis. Fight‐or‐flight responses are activated by the NS, which releases norepinephrine/noradrenaline and epinephrine/adrenaline in response to immediate stressors, whilst the HPA axis ...
Natarsha L. Babic, Christopher P. Johnstone, Slaven Reljić, Agnieszka Sergiel, Đuro Huber, Richard D. Reina   +5 more
wiley   +1 more source

Magnetic resonance spectroscopy investigations of brown adipose tissue and isolated brown adipocytes.

Journal of Lipid Research, 1994
Brown adipose tissue and collagenase-isolated brown adipocytes were investigated in rats by means of 1H and 13C nuclear magnetic resonance spectroscopy.
C Zancanaro, R Nano, C Marchioro, A Sbarbati, A Boicelli, F Osculati   +5 more
doaj  

Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with Human

Ожирение и метаболизм, 2015
Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with ...
Teona Albertovna Shvangiradze
doaj   +1 more source